... quantify-
ing airway remodeling throughout the tracheobronchial
tree in animal models of allergic airway disease.
It is our hypothesis that quantifying the extent of several
indices of airway remodeling ... remode-
ling in mice is the first systematic airway remodeling anal-
ysis of the tracheobronchial tree following chronic
allergen exposure. These f...
... might influence the clustering of dosage
compensation in the MHM valley is the evolutionary history
of this segment. The sex chromosomes of birds and
monotremes may have common origins, since the ... complete X-
inactivation and contains SOX3, the nearest X homologue of
the Y- linked testis-determining gene SRY [1,30-37]. If the
MHM valley represents the oldest pa...
... of interferon regulatory factor 3 is inhibited by the influenza
A virus NS1 protein. Journal Of Virology 2000, 74:7989-7996.
58. Min JY, Krug RM: The primary function of RNA binding by the influenza ... Our study also showed that
there are no genetic differences in receptor specificity or the cleavability of the haemagglutinin proteins of these
viruses regardless o...
... Technology and
by the State of Bavaria.
The work is part of the Community Medicine Research net (CMR) of the Univer-
sity of Greifswald, Germany, which is funded by the Federal Ministry of Educa-
tion ... use of medication influencing lung function
in the KORA study. However, the effect of diabetes in the
SHIP study disappeared when the analysis was restri...
... TNF-activated
NFB-DNA binding activity. The regulation of NFB-DNA
binding in primary cells can therefore be explained by the non-
specific effect of DMSO on NFB activation.
In the present study we determined ... cate-
gorized by the molecular function of their protein products into
categories that included hyaluronic acid binding activity
(including Agc1 and Hapln1) and...
... manually analyzed all these 40 modifications in
order to verify the effect of the repeats on the resulting pro-
teins. In the majority of cases, the reading frame of the origi-
nal protein is ... retention of
repeats that can significantly diversify the sequence of the
encoded proteins.
Fifty percent of variable ITRs modify protein sequences
In agreement with...
... homo-
zygosity of deleterious mutations may explain the
repeated success of asexuals in nature [32]. Whereas
any new insertions in a sexually recombining genome
can become homozygous, asexuals carry only ... Coordination
infrastructure for the DGC is provided by The Center for Genomics and
Bioinformatics at Indiana University, which is supported in part by the METACyt
Initia...
... play an essen-
tial role in reducing the severity of the I/R injury by
inhibiting neutrophil adhesion in postcapillary venules
and by decreasing microvascular constriction [20]. In our
study, ... at the 7 and 14 day reperfusion time-points. I/R
injury of sciatic nerve has been shown to increase proin-
lammatory cytokines which are primarly responsible
demyelinization after rep...
... of the potencial beneficial effects of statins in
cardiac surgery interventions.
List of abbreviations
CABG: Coronary artery bypass graft; CPB: Cardiopulmonary bypass; CPK:
Creatine phosphokinase.
Authors’ ... reduction of early and late
adverse events. The anti-inflammatory action of statins,
as we demonstrated [2], its pleiotropic effects and the
capacity of reduction o...