Báo cáo y học: " Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM" pps

Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx

Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx

... The increases in type I and III collagen mRNA were accompanied by increased immunostaining for these proteins in cartilage. The upregulated lumican expression in degenerative cartilage was associated with ... increased synthesis of collagens types I and III and a change in the relative levels of the fibril- associated SLRPs. In particular there is decrease in synthesis o...
Ngày tải lên : 09/08/2014, 06:23
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Báo cáo y học: "Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus" pps

Báo cáo y học: "Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus" pps

... of FCM analysis of GR binding by RLBAEvaluation of FCM analysis of GR binding by RLBA. Analysis of GR binding in (a) K562 and (b) U937 with and without 10 -6 M Dex by FITC-Dex- FCM and RLBA. ... Abnormalities of expression and binding of the GR may be involved in tissue resistance to steroids in SLE patients. Determination of GR expression and binding by FCM may b...
Ngày tải lên : 09/08/2014, 14:22
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Báo cáo y học: " Large scale comparison of global gene expression patterns in human and mous" pot

Báo cáo y học: " Large scale comparison of global gene expression patterns in human and mous" pot

... Identifying cycling genes by combining sequence homology and expression data. Bioinformatics 2006, 22: e314-322. 21. Lu Y, Mahony S, Benos PV, Rosenfeld R, Simon I, Breeden LL, Bar-Joseph Z: Combined ... Quality assessment of Affymetrix GeneChip data in bioinformatics and computational biology solutions using R and Bioconductor. In Bioinformatics and Computational Biology Sol...
Ngày tải lên : 09/08/2014, 22:23
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Báo cáo y học: "PLCb1-SHP-2 complex, PLCb1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?" ppt

Báo cáo y học: "PLCb1-SHP-2 complex, PLCb1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?" ppt

... ‘Shp’ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 2003, 28:284-93. 24. Qu CK: Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and ... G, Pessina AC: Reduced expression of regulator of G protein signaling-2 in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin I...
Ngày tải lên : 10/08/2014, 05:21
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Báo cáo y học: " Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells" docx

Báo cáo y học: " Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells" docx

... [19,39], or targeting MYCN or MDA5 may be helpful in augmenting the poly(I:C) sensitivity and NB immunotherapy. As an intracytoplasmic RNA sensor, MDA5 expression was higher in SK-N-FI (unpublished ... cells was evaluated by WST-1 cell proliferation assay, flow cytometry analysis, and immunoblot analysis. Blockade of TLR3 signaling was achieved using TLR3 neutralizing antibody,...
Ngày tải lên : 10/08/2014, 10:20
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Báo cáo y học: "Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury" pps

Báo cáo y học: "Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury" pps

... biological het- erogeneity inherent in primary cell studies and our pre- liminary findings need to be expanded upon and analysed individually in greater depth using techniques such as laser capture microdissection ... lines of in vitro evidence have pointed to a possible role for VEGF in lung repair and recovery following injury[19,29,35,36]. In one LPS- induced murine model...
Ngày tải lên : 12/08/2014, 14:20
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Báo cáo y học: "MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system" docx

Báo cáo y học: "MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system" docx

... acquired at 0. 8-2. 5 μm intervals. Selected depths were projected by a combination of maximum intensity and opacity. Sectioning Whole larvae and brains stained by whole-mount in situ hybridization ... 20, and Table D in Additional data file 27). In contrast, miR-34 expression is absent from forebrain and midbrain and present only in the caudal ventral and lat- e...
Ngày tải lên : 14/08/2014, 08:20
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Báo cáo y học: " support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation" pot

Báo cáo y học: " support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation" pot

... as reuse of linkage breakpoints is influenced by the fragility of certain types of sequence (see, for example, [51,52]). We start by examin ing the role of recombination and IGD in modu- lating ... genes contained within that wind ow were defined as belonging to a clus- ter. Adjacent or overlapping clusters were merged, as done by Spellman and Rubin [29]. Dynamic co -express...
Ngày tải lên : 09/08/2014, 22:24
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Báo cáo y học: " Dynamic gene network reconstruction from gene expression data in mice after influenza A (H1N1) infection." ppsx

Báo cáo y học: " Dynamic gene network reconstruction from gene expression data in mice after influenza A (H1N1) infection." ppsx

... called inflammasome, with apoptosis associated speck-like protein containing a caspase recruitment domain (ASC) and caspase-1 [59]. Activa- tion of casp ase-1 through Nlrp3 and ASC is necessary for ... characterized by terms associated to immune response, whereas the rest are mainly involved in metabolic process and system development. Time Varying Dynamic Bayesian Network Modeling...
Ngày tải lên : 10/08/2014, 09:22
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Báo cáo y học: " Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P" pptx

Báo cáo y học: " Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P" pptx

... engi- neering different designs of EGSs [29] for increasing their targeting activity, as well as developing new means for improving their delivery, are needed to increase the effi- cacy of the EGSs in ... BamH I and Hind III, and then inserted into vector pGEM3z (Invitrogen) to form a recombinant plasmid, UL49-pGEM3z. The RNA substrates were syn- thesized by bacteriophage T7 RNA p...
Ngày tải lên : 12/08/2014, 04:20
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