Báo cáo y học: "Participation of the PI-3K/Akt-NF-κB signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 " pot

... appears to be highly glycosylated in naturally infected SMs. Presumably, continually evolving antibody responses in these natural hosts maintain a highly glyco- sylated surface protein, albeit without ... ability of emerging pathogens to infect new species is likely related to the diversity of pathogen variants present in existing reservoirs and their degree of genomic plasticit...

Ngày tải lên: 13/08/2014, 09:21

... purposes) Respiratory Research Open Access Research Participation of the PI-3K/Akt-NF-κB signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells Qiangsong ... mecha- nism that involves reduced binding of GATA-2 to a palin- dromic GATA site in the 5'-UTR [30]. These findings indicate that the binding of speci...

Ngày tải lên: 12/08/2014, 16:20

... NAMI-A-mediated inhibition of ERK1/2 phosphorylation may be lying upstream of ERK1/2. Using a serine/threonine kinase SPA assay kit, the capability of NAMI-A to affect the ERK1/2 phosphoryla- tion activity ... maintenance of tumor cell growth [3]. The finding that the ERK signaling pathway is involved in tumor cell migration and invasion [4,5], as well as in tubular forma...

Ngày tải lên: 21/02/2014, 01:21

... fundamental roles in the pathogenesis of autoimmune diseases. Consequently, therapeutic targeting of B cells is gaining prominence in our clinical armamentarium for an ever expanding array of autoimmune ... issue is of central importance and is the focus of the article by Rouzière and coworkers [1]. Indeed, the breakdown of B cell tolerance for autoantigens may be at...

Ngày tải lên: 09/08/2014, 07:20

... those in the placebo group at week 2 (Tables 2, 3, 4, 5). Achievement of sustained PASS during the study Achievement of a sustained satisfactory symptom state according to PASS, maintained from the ... presentation of results at an individual level rather than a group level (as expressed by the mean change in symptom score) [2]. The challenge of the meeting was to dete...

Ngày tải lên: 09/08/2014, 10:20

... cases into different category. It is rather a differ- ence of frequency, not justifying B-IVL in Asian countries as Asian variant. The frequency of hemophagocytosis was relatively low (19%) in Sa ... Chihara et al.: Frequency of intravascular large B-cell lymphoma in Japan: Study of the Osaka Lymphoma Study Group. Journal of Hematology & Oncology 2011 4:14. Submit your...

Ngày tải lên: 10/08/2014, 21:23

... α7 nicotinic acetylcholine receptor, it was necessary to show if expression of the α7 nicotinic acetylcholine receptor protein in seen in these cell lines. Using a specific anti- body for the α7 ... upregulation of the α7 nAChR in the lungs of the newborns [24]. Together these data indicate that the α7 nAChR may play an impor- tant role in the development of SCLC...

Ngày tải lên: 12/08/2014, 18:21

... tions. We hypothe sized that the l ack of non-synonymous mutations was a result of the structural constraints on Gag. One would thus expect to see a higher rate of non-synonymous muta- tions in Nef. ... gag and nef in HLA-B*57 positive ES. We previously showed evolution in the gag gene of ES which surprisingly was mostly due to synonymous mutations rather than non-synonymo...

Ngày tải lên: 13/08/2014, 01:20

... association between family size and hay fever led to the hypothesis that reduced microbial exposure in early life increases the risk of developing allergic diseases (the "hygiene hypothesis") ... would suggest the key factor is the alteration of the gut microbi- ota as a whole. Number of bands and Shannon diversity index by mode of deliveryFigure 3 Number of...

Ngày tải lên: 13/08/2014, 13:22

... or of one being from the UK and the other from Denmark. There is presently an ongo ing validation of the SBT-cut points in Danish primary care that will reveal whether the scale should be interpret ... patients, the SBT risk groups did relate to risk of non-recovery after 6 months. If the d omains included in the SBT are modifiable, as they instinctively would be, this...

Ngày tải lên: 13/08/2014, 15:21