Báo cáo y học: " The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations" doc
... fwd ACGTTGGATGGGGCACCAATTAACTAAGGC
rev ACGTTGGATGTGAGGGCATGGAAGGTTCAG
GCCGGCTCCCAAGCTCC 92.03
S1 rs3918396 G /A 0.09 0.09 fwd ACGTTGGATGAGTCGGTAGCAACACCAGGC
rev ACGTTGGATGAATCCCCGCAGACCATGACAC
CCTGCTGGCCATGCTCCTCAGC ... 12
(page number not for citation purposes)
Respiratory Research
Open Access
Research
The role of polymorphisms in ADAM33, a disintegrin and
metalloprotease...
... CTTGCATGCCCTGCAGGTCG
Mutagenic L73G Forward GTATTCAAAAGTGGTCCCGGACAAAATGAG GACTTG
Reverse TCCGGGACCACTTTTGAATACTTTCAAGTGCATATATTTATT
P74G Forward CAAAAGTCTTGGCGGACAAAATGAGGACTTGGTAC
Reverse CATTTTGTCCGCCAAGACTTTTGAATACTT ... binding loop of cystatin A fulfils the
same function as the second binding loops of cystatin B and
family 2 cystatins and also what residues of this loop...
... may
in uence the shape and volume of the acyl binding pocket
and thereby alter the binding mode and affinity of the
enzyme for PAA and derivatives thereof, while maintaining
the hydrophobicity of ... The
bF24rv mutagenic primer was 5¢-ATAAGTATACGCAG
GCGCATACCAGCC
AAACTGCGGGCCATTTAC-3¢
and the bF57rv mutagenic primer was 5¢-GGAAATC
ACACCATTATGACCA
AAAACCAGCCCGGGAT...
... activity
and in distinct changes in the zinc ligands. In the
His237 fi Ala and Cys239 fi Ala mutants, coenzyme M
also seemed to bind efficiently by ligation to zinc indicating
that some aspects of ... zinc.
XANES spectra of wild-type and mutants
As shown in the following, the interpretation of the EXAFS
of the mutant enzymes is confirmed by a comparative
analysi...
... proposed roles for these residues in
binding the carboxylate linked to the nucleus of penicillin N
(Arg160 and Arg162) and the carboxylate of the a- amino-
adipoyl side-chain (Arg266). The results ... Taiwan;
3
Department of Pharmacy and Pharmacology, The University of Bath, UK
Deacetoxycephalosporin C synthase (DAOCS) catalyses the
oxidative ring expansion of...
... scores, the use of
heat-inactivated Lactobacillus GG was associated with
adverse gastrointestinal symptoms and further study
enrollment was thus halted.
Another study by Kirjavainen et al suggested ... composition of gut microbiota
of allergic infants. a target of bifidobacterial therapy at wean-
ing? Gut 2002, 51(1):51-5.
8. Kirjavainen PV, et al.: Characterizing the composit...
... func-
tional activity of a glucocorticoid-regulated inflammatory
cyclooxygenase. Proc Natl Acad Sci USA 1992, 89:4888-4892.
7. Raskin JB: Gastrointestinal effects of nonsteroidal anti-inflam-
matory therapy. ... manage
acute pain. Moreover, whereas the use of these drugs in
the management of acute pain is typically short term (a
few days to two weeks), their continuous usag...
... of
α-subunits, and two transactivating domains, namely the
amino-terminal transactivating domain and the carboxyl-
terminal transactivating domain (C-TAD). The C-TAD has
been shown to interact with co-activators ... activating
angiogenesis, hypoxia may regulate many other features that are
important in RA, such as cell trafficking and matrix degradation. An
understanding of...
... Weichselbaum in the Archives for
Pathology, Anatomy, Physiology and Clinical Medicine in 1878. (c)
Title of the manuscript, meaning The finer changes of joint cartilage in
fungous synovitis and caries ... Nagashima M, Yamamoto M, Nishijima T, Katsumata
S, Yoshino S: Bone resorption and inflammatory inhibition effi-
cacy of intermittent cyclical etidronate therapy in r...
... 3-
hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reduc-
tase enzyme. These include naturally occurring lovastatin,
chemically modified simvastatin and pravastatin [1–3] and
the synthetically derived atorvastatin, ... Comparison, structure and organization of bone
and other mineralized tissues and the mechanism of calcifi-
cation. In: Handbook of physiology, endocrinolog...