Báo cáo y học: " Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D" pdf

... Research Open Access Research Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D S Kierstein 1 , FR Poulain 2 , Y Cao 1 , M Grous 3 , R Mathias 2 , ... have previously shown that a rapid release of pro-inflamma- tory cytokines is followed by a relatively slow, gradual ele- vation of SP-D protein...

Ngày tải lên: 12/08/2014, 16:20

... significant. Results Clinical and histological severity of arthritis Mice with signs of inflammation at any time point during the observation period were included in the analysis of the severity of arthritis. In four ... without any cartilage or bone destruction. (c) The synovial lining layer is composed of flat synovial cells or is mildly hyperplastic. (d–f) Joints of tra...

Ngày tải lên: 09/08/2014, 01:23

... production of rheumatoid factor (RF) IgM is one of the hallmarks of RA and is frequently associated with more severe disease. Other autoantibodies detectable either in serum or in synovial fluid of RA ... retrospective study, the frequency of B cells was determined as a percentage of CD19 + lymphocytes from total T lymphocytes and B lymphocytes combined (CD3 + + CD19 + lym...

Ngày tải lên: 09/08/2014, 03:24

... (Dundee, UK) (cutoff value = 5 units/ml). Rheumatoid factor of the IgM isotype was determined using the agglutination test with sen- tized sheep erythrocytes as originally described according to Waaler-Rose ... according to autoantibody Table 2 Frequency distribution of the 1858 C/T polymorphism of PTPN22 in patients with early rheumatoid arthritis and matched controls Genotype...

Ngày tải lên: 09/08/2014, 10:20

... shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987, 30:1205-1213. 18. Sambrook P, Fritsch E, Maniatis T: ... Cornelis F: IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis. Ann Rheum Dis 2007, 66:828-831. 24. Spiel...

Ngày tải lên: 09/08/2014, 10:20

... co-morbidity with generalized anxiety disor- der, panic disorder, depressive disorders, and bipolar disorder in adults [9]. Asthma is to a similar degree associated with the same anxiety disorders and with bipolar ... possibility is that inflammatory mechanisms may be a common factor for these disorders. Such mechanisms are important in the pathophysiology of asthma [54,55], a...

Ngày tải lên: 11/08/2014, 15:22

... diversity is inversely correlated with CD4 T cell counts and is associated with rapid dis- ease progression [47]. Together, these results may imply that evolutionary forces that drive HIV-1 subtype ... intra-patient diversity analysis for slow progressors for different regions of the Env gene for study entry and study exit. Figure 3C Box and whisker plots of intra-patient divers...

Ngày tải lên: 13/08/2014, 01:20

... of animals with symptoms of AIDS. At this stage of the infection, A3G and A3F mRNA levels once again seem to be governed solely by interferons as they correlated with the transcription of ISGs. An ... (Milte- nyi Biotec, Bergisch-Gladbach, Germany) and monoclonal antibodies to either CD4 or CD14. The purity of the iso- lated CD4+ T-cells and CD14+ monocytes were analyzed b...

Ngày tải lên: 13/08/2014, 01:21

... the x axis. It is evident that patients with higher body mass index were no more likely to receive increased parenteral calories. Table 4 Multivariate analysis of factors associated with bloodstream ... regression to analyze the effects of multiple potential risk factors on the development of BSI. Adjusted odds ratios are presented with 95% confidence intervals from this...

Ngày tải lên: 13/08/2014, 08:20

... evidenced by the myriad of diseases that occur when polymorphisms of ABCB4 cause com- plete or partial protein dysfunction. ABCB4 deficiency is associated with a variety of hepatobiliary disorders ... lining the bil- iary system from the cytotoxic detergent actions of bile salts [3-5]. Bile salt cytotoxicity is substantially reduced in the presence of PC owing to the for...

Ngày tải lên: 13/08/2014, 13:20