Báo cáo y học: " Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness" pot
Báo cáo y học: " Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness" pot
... AccessResearch Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsivenessChi-Ling Fu1, Yi-Ling Ye1, Yueh-Lun Lee2 and Bor-Luen Chiang*3Address: ... role IL-10 in regulat-ing airway inflammation. In addition, TGF-β inhibits theproduction of proinflammatory cytokines from macro-phages, B cells, and T cells and is a potent inhibitor of Tcell-mediated ... Lee YL, Fu CL, Ye YL, Chiang BL: Administration of interleukin-12 prevents mite Der p 1 allergen- IgE antibody production and airway eosinophil infiltration in an animal model of air-way inflammation....
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Báo cáo y học: " Ethnobotany, diverse food uses, claimed health benefits and implications on conservation of barley landraces in North Eastern Ethiopia highland" ppsx
... qualities and diversity of landracesCrop selection and m aintenance decisions are generallymade based on a set of criteria that has resulted in acomplex and continually evolving collection of land-races. ... meherseason depending on the onset of the rainfall. For exam-ple, the b elg rain occasionally starts very early making itpossible to plant late maturing types including the onesusually grown during ... rainfall condition of the season, soil type and fertility, maturity, frost toler-ance, yield and other factors. Consequently, althoughfarmers’ practices enabled on- farm conservation of many landraces,...
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... expression, which is induced by AGE,can contribute to the inflammatory cycle by the induction of proinflammatory cytokines, via the nuclear factor-κBpathway [21]. No studies have yet examined ... of these autoantibodies are present in only a subset of RA patients in early stages of disease [1].The relationship between the synovial and systemic inflam-matory response and production of ... increase in the spondyl-arthropathy group and, conversely, fall slightly in the RAgroup at the second visit. This may reflect the lower use of prednisone in the spondylarthropathy patients during...
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Báo cáo y học: "Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis" pdf
... unlikely based on history,clinical features along with distribution of blisters, and course of disease in relation to intake of naproxen. Long-term informa-tion was obtained by review of follow-up ... affected by EOPA-JIA in our cohort werepredominantly of Scandinavian ancestry, and so fair skin ismore likely to be present in these children. In addition, they aregenerally young, making early age ... increase in naproxendosage and use of comedications are mostly a consequence of increased disease activity. As indicated in the present studyJIA disease activity, as indicated by laboratory...
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Báo cáo y học: " Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells" docx
... role of TLR3 signaling in differentiation and apoptosis in NB.Figure 6 Effect of TLR3 neutralization on poly(I:C) -induced apoptosis in SK-N-AS cells. (A) Effect of TLR3 neutralization on poly(I:C) -induced caspase-3 ... Application of TLR3 neutralizing antibody or small interference RNA (siRNA) reduced the poly(I:C) -induced inhibition of cell proliferation and apoptosis in SK-N-AS cells. On the contrary, ectopic ... phosphorylation -induced activation in virus-infected cells and plays an important role in the antiviralinnate immune response under the regulation of PKR[26]. It was found that application of poly(I:C)...
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Báo cáo y học: "A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice" pps
... to PDE4 only inhibitors. Thisstudy therefore examined the in vitro and in vivo potency of a combination of phosphorothioate AONs directedagainst PDE4B/4D and PDE7A subtypes. These AONsincorporate ... illustrated by dose-dependent inhibition of IL-8 and MCP-1 secretion. The potency of combined PDE4B/4D and 7A AON on inflammatory markers in vitro is in line with their protective effect in vivo, ... Inhibition of Antigen -induced Eosinophilia and Airway Hyperresponsiveness by AntisenseOligonucleotides Directed against the Common beta Chain of IL-3, IL-5, GM-CSF Receptors in a Rat Model of...
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báo cáo hóa học:" CCR9 interactions support ovarian cancer cell survival and resistance to cisplatin-induced apoptosis in a PI3K-dependent and FAK-independent fashion" pdf
... might be involved in OvCa cell survival and inhibition of cisplatin -induced apoptosis. In this study, we investigated the potential role and molecular mechanisms of CCR9-mediated inhibition of cisplatin -induced ... 3:15http://www.ovarianresearch.com/content/3/1/15Page 7 of 8Chemokines-chemokine receptor interactions also sup-port integrin clustering, which also increase FAK activa-tion. FAK is a cytoplasmic protein tyrosine kinaseinvolved in the regulation ... along with increasing concentrations of cisplatin. Cell prolifera-tion was determined by BrdU incorporation and assays were repeated 3 times and performed in triplicate. Asterisk(s) (*) indicate...
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Báo cáo y học: "Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes"
... multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, ... reported in previous studies involving p-synephrine [17, 18]. The increase in RMR between Group 4, the combination of p-synephrine with 600 mg naringin and 100 mg hesperidin, and the placebo control ... no effects on heart rate or blood pressure were observed in response to p-synephrine or p-synephrine in combination with naringin and hes-peridin (Table 2). p-Synephrine differs from ephedrine...
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Báo cáo y học: "Effects of Flurbiprofen on CRP, TNF-α, IL-6, and Postoperative Pain of Thoracotomy"
... Department of Thoracic Surgery, Konya Education and Research Hospital, Konya, Turkey; 2. Microbiology Laboratory, Konya Education and Research Hospital, Konya, Turkey Corresponding author: ... proteins. Proinflammatory cy-tokines induce not only a local inflammation at the site of injury, but also systemic responses such as tachycardia, tachypnea, leukocytosis, and pyrexia (1). Increased ... Thoracotomy pain, Inflammatory response, Flurbiprofen Introduction Surgical trauma induces an inflammatory state characterized by the release of both proinflammatory and antiinflammatory proteins....
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Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"
... Beyer EC, Saffitz JE. Effects of angiotensin II on expression of gap junction channel protein connexin43 in neonatal rat ventricular myo-cytes. J Mol Cell Cardiol. 1998; 32: 800-7. 15. Polontchouk ... present study aimed to detect the expression of Cx40 and Cx43 in the artery at early stage of high fat diet induced atherosclerosis and to investigate the effects of AT1 antagonist Losartan on the ... Cx43 and Cx37 have been identified in the VSMCs (2). A variety of in vitro and in vivo experiments have proved that GJ may be involved in the injury or dis-ease induced activation of vessel...
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