Báo cáo y học: " Inhalation of β2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract" pptx

... infection of the airways with P. aerugi- nosa is the leading cause of morbidity and mortality in the majority of CF patients (1). This pathogen colonises the airways and lungs often in the late ... used in two clever ways to facilitate its pathogenicity. First of all, the lectins attach to the covering epithelia by binding to the glycocalix of the mammalian cells...

Ngày tải lên: 03/11/2012, 11:48

... writing of the manuscript. CB contributed to the design of the study, to the collection of the data, to statis- tical analysis and to the writing of the manuscript. IL contrib- uted to the design of ... the design of the study and to the interpretation of the results. LP had the main responsibility for the genetic analyses and contributed to the ana...

Ngày tải lên: 09/08/2014, 07:20

... the prediction of MCT prognosis [12]. Surgery was performed equally often on MCT located on the trunk and on extr emities even though the latter location often impairs the use of wide surgery ... aspiration s of MCT are usually rich in cells as these exfoliate easily and cytology is usually sufficient for a diagnosis of MCT. However for grading of the tumours, histopatho...

Ngày tải lên: 12/08/2014, 18:22

... of 10 (page number not for citation purposes) Respiratory Research Open Access Research Inhalation of β2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory ... [40]. Conclusion Our study suggests that, at least in mice, inhalation of β2 agonists impairs the clearance of NTHi from the airways. Ob...

Ngày tải lên: 12/08/2014, 16:20

... part by a research grant from the Italian Society of Hypertension (SIIA) to LAC, by a grant from Italian Ministry of the University and Scientific and Technological Research (MURST) to GC and by a ... characteristics, likely will signifi- cantly expa nd the number and complexity of the signal- ing pathways through which Ang II signals and thereby might provide new potential...

Ngày tải lên: 10/08/2014, 05:21

... possible because of an attitude change on the part of the endocrinologists. Now they say 'you GPs have to do the job, but call me when necessary.' This is a big change from the usual 'let ... Prevention of these compli- cations rests on timely institution of drug therapy by the prescribing physician, usually a general practitioner (GP), and the patient&apo...

Ngày tải lên: 11/08/2014, 05:21

... prostaglandin synthesis [40], and S-nitrosylation of COX-2 activates the enzyme and contributes to cell injury [41,42]. The impact of the co-induction of iNOS and COX-2 in endothelium requires further ... by an inhibitor of calpain. Given the sensitivity of COX-2 and iNOS to calpain, PIN1 may normally limit induction of these and other calpain substrates by maintaining cal...

Ngày tải lên: 11/08/2014, 08:22

... fluorescent dye (e.g., IRDye® 800), and detected by using the Odyssey Imaging System. Densito- metry was then performed to quantify SPLUNC1 pro- tein levels. Intracellular SPLUNC1 protein of human epithelial ... induce inflammatory cytokine (e.g., IL-6) and airway epithelial mucin production [17]. In the current study, we hypothesize that SPLUNC1 expression is in large part under the...

Ngày tải lên: 12/08/2014, 11:23

... significantly inhibited by Y- 27632 inhalation to a considerable extent. The AHR after the EAR was strongly reversed by Y- 27632 inhalation to a hyporesponsive level as compared to basal airway responsiveness ... inside the thoracic cavity. The free end of the catheter was driven subcutaneously to the neck of the animal, where it was exposed and attached perma- nently....

Ngày tải lên: 12/08/2014, 16:20

... that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms. Conflict of Interest The authors have declared ... rate, we consider that it is es- sential to systematically monitor the counterpart of the symptomatic patient, irrespective of the absence of symptoms. At last, Twin...

Ngày tải lên: 25/10/2012, 11:00