Báo cáo y học: " Upper airway dynamics during negative expiratory pressure in apneic and non-apneic awake snorers" pot
... collapsibility of the upper airways which can be easily assessed looking at the early expiratory flow dynamics after NEP application during tidal breathing and properly measured as V,NEP 0.5 and V,NEP 1 . ... V,NEP 0.5 and V,NEP 1 values for the baseline expiratory flows and Supine tidal flow-volume curves (control and during NEP of -5 cmH 2 O) and corresponding expi...
Ngày tải lên: 12/08/2014, 16:20
... other antibodies – including those directed to platelet cytokines and other surface receptors – and platelet activation may therefore be important in determining clinical outcomes. Commentary Heparin-induced ... exposure. Using an initial priming solution containing 10,000 IU heparin, followed by a heparin infusion, may therefore have accounted for the increased incidence of HIT (8%) re...
Ngày tải lên: 13/08/2014, 11:22
... fol- lowing reduced spinal stability in t hese patients [ 26]. The spinal stabilizing system was primarily described by Panjabi [28], including of 3 subsystems: the spinal col- umn providing intrinsic ... providing intrinsic stability; spinal muscles, providing dynamic stability and neural control unit con- trolling and determining the requirements for stability and coordinating the m...
Ngày tải lên: 13/08/2014, 15:21
Báo cáo y học: " Early fiberoptic bronchoscopy during non-invasive ventilation in patients with decompensated chronic obstructive pulmonary disease due to community-acquired-pneumonia" ppt
... study with the aims, firstly, to verify the safety and effectiveness of early thera- peutic FBO to clear airways during NPPV and, secondly, to compare the hospital outcomes of this strategy admin- istered ... pilot study was, firstly, to verify the safety and effectiveness of early FBO during NPPV and, secondly, to compare the hospital outcomes of this strategy versus a CMV-based...
Ngày tải lên: 13/08/2014, 20:22
Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... expression increased in the aging thymus. The CCR5 ligands, CCL4 and CCL5, increase in the thymic parenchyma as revealed by the age-associated increases in the staining of thymocytes and microenvironmental ... Obviously, much more work is needed to understand the crosstalk and interregulatory rela- tionships between chemokines and cytokines, mes- enchymal cells and adipoc...
Ngày tải lên: 08/08/2014, 18:20
Báo cáo y học: " Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer’s disease pot
... of the study and participated in its study and coordination. Both authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: ... imaging (MRI), and single photon emission computed tomogra- phy (SPECT) were also performed. Brain CT showed brain atrophy and ventricular enlargement, and MRI showed small i...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt
... gelatin zymography, and collagenase activity assays using both SW1353 chondrosarcoma cells and primary human chondrocytes. The HDAC inhibitors trichostatin A and sodium butyrate potently inhibit ... collagenases, and Figure 1 Histone deacetylase inhibitors block cartilage glycosaminoglycan and collagen loss induced by IL-1α/OSMHistone deacetylase inhibitors block cartilage glycosami...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics" pot
... previous meeting in this series, and further clinical trials seem likely. Introduction Every 3 years, a loosely affiliated network of investigators holds an informal, 2-day meeting to discuss progress in ... efficacy in rat streptococcal cell wall induced arthritis [44], a model of RA, and the clinical vector has proved safe in monkeys. During the phase I study, the vector is in...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts" potx
... Alkaline phosphatase activity was determined on cell aliquots by substrate hydrolysis using p-nitrophenylphos- phate, and osteocalcin release was determined in cell super- natants using an enzyme ... was rapidly phosphorylated upon IGF-1 stimulation, yet Syp showed a poor interaction with IRS-1. In contrast, Syp was highly phosphorylated in OA Obs and its interaction with IRS-1 was...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx
... inhibitor Apolipoprotein A α 1 -Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H 4 inhibitor α 1 -Antichymotrypsin Pregnancy zone protein Gelsolin α 1 -Acid glycoprotein Fibrinogen S100 Kinninogen ... formation and breakdown of kinins results in the inflammation, joint pain, and swelling that are seen in patients with arthritis. Our analyses identify members of the p...
Ngày tải lên: 09/08/2014, 10:20