Báo cáo y học: "Hormonal regulation of alveolarization: structure-function correlation" ppt

... University of Pennsylvania School of Medicine, Philadelphia, PA, USA and 3 Division of Neonatal-Perinatal Medicine, Division of Pulmonary and Vascular Biology, Room K4.224, University of Texas ... signifi- cant cause of morbidity and mortality affecting as many as 30–40% of infants born less than 30 weeks gestation [1]. While the pathophysiology of BPD includes both inflam-...

Ngày tải lên: 12/08/2014, 16:20

... aim ofthis studywas to characterize the role of an acyl-CoA thioesterase (ARTISt) and an acyl-CoA synthetase as members of an alternative pathway in the regulation of the intracellular levels of ... activity in Y1 cells. This points to a direct effect of ACTH upon enzyme activity. However, we cannot rule out a possible activation of the enzyme by an ACTH- mediated increased ava...

Ngày tải lên: 08/03/2014, 09:20

... stress by redirect- ing t he synthetic machinery towards the synthesis of s ome enzymes involved in glycolysis or sugar-phosphate metabolism [54]. HydA belongs to a new class of Fe-hydrogenases HydA ... they often catalyze the reduction of pr otons with a high specific activity to yield hydrogen [16]. Interestingly, Fe-hydrogenases were not found in cyanobacteria, the free-living ancesto...

Ngày tải lên: 08/03/2014, 22:20

... differen- tiation in erythroid progenitors. Polycytemia vera is a clonal myeloproliferative disorder, leading to hyperproliferation of erythroid, myeloid and megakaryocytic cells. Sixty percent of polycytemia ... survival of early hematopoietic cells, at the expense of differenti- ation. The proto-oncogene c-Myb c-Myb is abundantly expressed in immature hematopoietic cells of erythr...

Ngày tải lên: 08/03/2014, 22:20

... telomerase activity was measured by TRAP/EIA cells 3 days later. (C) Telomerase activity after introduction of antisense oligonucleotides into PHA- stimulated lymphocytes. Ficoll-Hypaque isolated lymphocytes ... inhibition of TEP1 function by high concentra- tions of antisense oligonucleotides, telomerase activity was dramatically diminished. Alternatively, hTR and hTERT may play a mini...

Ngày tải lên: 17/03/2014, 23:20

... Brinck- erhoff CE: A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflamma- tory cytokines. Arthritis Rheum 2001, 44:1096-1104. 64. Suh N, Wang Y, ... in inflammatory arthritis. J Clin Invest 2000, 105:1799-1806. Arthritis Research Vol 4 No 3 Vincenti and Brinckerhoff to the transcription of an array of inflammatory genes, their dir...

Ngày tải lên: 09/08/2014, 03:24

... to bind to Tyr757 of gp130, Tyr985 of the leptin receptor and Tyr401 of the erythropoietin receptor, Tyr729 of the granulocyte colony-stimulating factor (G-CSF) receptor, Tyr800 of the IL-12 ... 279: 54708-54715. 66. Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, Rottapel R, Yamaoka S, Lu KP: Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ub...

Ngày tải lên: 09/08/2014, 06:23

... Jr, Yarboro CH, Arayssi TK, Pando JA, Kanik KS, Gourley MF, Klippel JH, Wilder RL: In vivo gene expression of type 1 and type 2 cytokines in synovial tissues from patients in early stages of rheumatoid, ... progression of structural damage of the joint bone structure as measured by X-ray analysis. The RA joint synovial fluid and synovium contain a variety of hematopoeitic cells that...

Ngày tải lên: 09/08/2014, 13:21

... Loss of expression of KLF17 by transcriptional suppression or inactivation by post-translational modification (possibly by phosphorylation or dephosphorylation) leads to transcription of ID1 ... amino-terminal region of KLF17. Given that the activity of some Sp1/KLF family members is known to be regulated by PKC isoforms [8,24-26], it is plausible that the ability of KLF17 to...

Ngày tải lên: 09/08/2014, 20:20

... details 1 Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan. 2 Department of Cardiovascular, Thoracic, and Pediatric Surgery, Yamagata University School of ... Ohta J, Tada H, Minatoya Y, Sakuma M, Watanabe J, Goto K, Shirato K, Kagaya Y: Differential regulation of diacylglycerol kinase isozymes in cardiac hypertrophy...

Ngày tải lên: 10/08/2014, 09:21