Báo cáo y học: " Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo" pot
Báo cáo y học: " Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo" pot
... citation purposes) Respiratory Research Open Access Research Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo Uta Griesenbach* 1,10 , ... delivering asODN and siRNA to the airways. We administered FITC-labelled siRNA and asODN (160 µg/mouse) complexed to GL67 to the mouse lung using a st...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo Y học: The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea pot
... of significant contaminant by nucleotide. Assay of enzyme activity The activity of the shikimate kinase was determined by a double coupled assay involving pyruvate kinase (PK) and lactate dehydrogenase ... of enzyme Stability of the enzyme. The loss of secondary and tertiary structure during unfolding of SK by urea were monitored by changes in far UV CD and fluorescence, respectively. O...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum docx
... of single enzymes. Some examples are D -hydantoinase/N-carbamylase [7], b-galactosidase/galac- tokinase [8], citrate synthase/malate dehydrogenase [9], aminocyclopropane-carboxylic acid synthase/aminocyclo- propane-carboxylic ... Some unspecific binding of E. coli proteins appeared to occur on all three ions, which may be due to the presence of metal binding sites in some proteins. In...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: " A comparison of olanzapine and risperidone on the risk of psychiatric hospitalization in the naturalistic treatment of patients with schizophrenia" ppsx
... findings may help clinicians in choosing between olanzapine and risperidone or assist decision makers when considering the need to maintain open and unre- stricted formulary access to olanzapine. ... per patient in the year following initiation, and (c) time to hospitalization, defined as the number of days from initi- ation to the first hospitalization during the year post...
Ngày tải lên: 08/08/2014, 20:23
Báo cáo y học: "The contact-mediated response of peripheral-blood monocytes to preactivated T cells is suppressed by serum factors in rheumatoid arthritis" ppt
... concentration and inhibitory serum activity is remarkable. The results are best explained by additional inhibitory factors that seem to be present in RA sera and seem to bind to the monocyte cell ... TNF-α response in T cell co-cultures, indicating that inhibitory factors do indeed bind to monocyte surfaces, which might represent a regulatory counter-action of the immune syste...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Drug efficacy by direct and adjusted indirect comparison to placebo: An illustration by Mycobacterium avium complex prophylaxis in HIV" potx
... al. study to baseline characteristics in Nightingale et al., using the rifabutin arms in each study, we estimated the efficacy of clarithromycin in Benson et al. compared to placebo in Nightingale ... other. Efficacy by direct comparison We used data from three studies, by Nightingale et al., Pierce et al., and Oldfield et al.tocomparerifabutin, clarithromycin, and azithromyci...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: "Comparison between partial ulnar and intercostal nerve transfers for reconstructing elbow flexion in patients with upper brachial plexus injurie" pot
... Surgery, Graduate School of Medicine, Kyoto University, 54 Shougoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan. 2 Department of Rehabilitation Medicine, Kyoto University Hospital 54 Shougoin ... the MMBbranchoftheMCNalsoincludesmanymotor axons [1,2]. In contrast, the motor branch (main trunk) of the ICN includes not only motor axons innervating the inter costal muscles but also axons ser...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Comparison of the systemic and pulmonary inflammatory response to endotoxin of neutropenic and non-neutropenic rats" pps
... Gauldie J: Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macro- phage inflammatory protein-2, interleukin-1 beta, and inter- leukin-6 but ... of cytokines, specialized cytokines called chemokines and cell adhesion molecules [9]. Chemokines belong to a superfamily of cytokines that promote chemotaxis of leu- kocytes to ar...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Systematic review of safety and tolerability of a complex micronutrient formula used in mental healt" pptx
... findings such as these increase the likelihood that research and clinical use of complex micronutrient formulae w ill continue to expand in the coming years. Hence, information on safety and toler- ability ... amounts and combinations of nutrients they contain. As these complex formulae are being studied and used clinically with increasing frequency, there is a need for direct eva...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats" pot
... of hydroxyproline content. Hydroxyproline assay was per- formed according to the instruction of hydroxyproline test kit from Nanjing Jiancheng Bioengineering Institute (Nanjing, China). In brief, ... were homogenized by a Polytron tissue homogenizer in saline containing 0.1 M phenylmethylsulfonylfluoride. The homogenized sample was hydrolyzed in 6 N HCl, and the hydroxyproline conce...
Ngày tải lên: 12/08/2014, 14:20