Báo cáo y học: " Epigenetics and airways disease" potx
Báo cáo y học: " Epigenetics and airways disease" potx
... MTA2 and SDS3, which can subsequently stimulate its activity and consequently enhance its enzymatic activity [46]. Similarly, HDAC2 phosphorylation is necessary for both enzymatic activity and ... complexes also alters lysine specif- icity. On free histones Gcn5 alone acetylates mainly H3 lysine 14, SAGA acetylates lysines 9, 14, 18 and 23, and ADA acetylates 9, 14 and 18 [35,39]....
Ngày tải lên: 12/08/2014, 16:20
Báo cáo y học: "Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link" docx
... published by Feig and colleagues [10], by Baker and colleagues [11], and by Edwards [12]. Serum urate and vascular effects in laboratory and animal studies Using a rat animal model in which hyperuricemia ... described. Eighty patients younger than 35 years of age clinically diagnosed with an acute myocardial infarction were divided among those patients who had coronary artery diseas...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo Y học: Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot
... Science, and Technology of Japan, and by an Industrial Technology Research Grant Program from the New Energy and Industrial Technology Development Organization (NEDO) of Japan, and also by the Intramural ... and HIII) by the subunit structure. Prokaryotic type 2 RNases H are functional in a monomeric form [25,28], similar to prokaryotic [13,18,20] and eukaryotic [21] type 1 RNases...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo y học: "Epigenetics, Behaviour, and Health" ppt
... DNA Methylation and Demethylation: Chromatin and DNA Methylation Methylation and demethylation enzymes do not have exquisite sequence specificity; how could these enzymes maintain highly specific ... moshe.szyf@mcgill.ca. DOI 10.2310/7480.2008.00004 Allergy, Asthma, and Clinical Immunology, Vol 4, No 1 (Spring), 2008: pp 37–49 37 whereby methylated cytosines are replaced by unmethy- l...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Phenomenology and management of cognitive and behavioral disorders in Parkinson''''s disease. Rise and logic of dementia in Parkinson''''s disease" pptx
... existence of three types of pathology possibly causing cognitive impairment in PD: Lewy-body-type degeneration in corti- cal and limbic structures, coincident AD-type pathology in cortical and limbic ... disease: a randomized controlled study. J Neurol Neurosurg Psychiatry 2002, 72:708-712. 55. Edwards KR, Hershey L, Wray L, Bednarczyk EM, Lichter D, Farlow M, Johnson S: Efficacy and sa...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers" doc
... 19:1187-1194. 14 Kim YM, Jang JW, Lee OH, Yeon J, Choi EY, Kim KW, Lee ST, Kwon YG: Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix ... SSc 1400 1200 1000 800 600 400 200 0 (a) (b) Capillaroscopy and VEGF levels Serum levels of VEGF were increased in all capillaroscopy groups (early, active and late) compared with...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet''''s disease" docx
... antigens, Sip1 in our study and α-enolase in the study by Lee and colleagues, were recognized only by IgM of patients with BD and patients with other forms of primary vas- culitis, whereas no ... library, conducted the ELISA experiments and participated in the design of the study and analysis of the data. FC participated in the design of the study and in the anal- ysis of data an...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... multicellular inflammatory process, including infiltration of lymphocytes and granulocytes into the articular cartilage, proliferation of synovial fibroblasts and macrophages and neovascularization of the synovial ... inflammatory cytokines in RA patients by inducing anti-inflammatory cytokines or neutralizing pro-inflammatory cytokines should be critically evaluated before considering...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study" pptx
... compared with healthy controls and patients with osteoarthritis [6,7]. Measures of disease activity and severity such as C-reactive protein (CRP), disability index, pain, and global severity are associated ... citrulli- nated peptide antibody (anti-CCP) by enzyme-linked immuno- sorbent assay (ELISA) (Inova Diagnostics, San Diego, CA, USA) and CRP by phyCardioPhase high-sensitivity CRP...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Development and validation of the self-administered Fibromyalgia Assessment Status: a disease-specific composite measure for evaluating treatment effect" pptx
... two psychometrically based summary measures: the physical component summary scale score (PCS) and the mental component summary scale score (MCS) [25]. Statistical analysis Following standard ... sensitivity and specificity, and then used to com- pute the optimal cut-off value corresponding to the maximum sum of sensitivity and specificity. Wilcoxon's signed rank test and Fisher...
Ngày tải lên: 09/08/2014, 14:22