Báo cáo y học: " Wnt signalling in lung development and diseases" pot
Báo cáo y học: " Wnt signalling in lung development and diseases" pot
... Furthermore, dominant negative and antisense Wnt5 a
and anti-Fz-5 antibody block Wnt5 -Fz5 signalling leading
to decreased cytokine production [33].
Additionally, the inflammatory cytokine inducing Wnt5 a
has ... on indirect evidence a role for Wnt signalling in
inflammatory lung diseases can also be postulated. Cer-
tainly, better understanding of Wnt signalling in the...
Báo cáo y học: "Growth factors in lung development and disease: friends or foe?" pptx
... Williams ST, Lee H, Malicki DM, Chin EM, Yin S, Tapley J,
Ulich TR: Keratinocyte growth factor ameliorates radiation-
and bleomycin-induced lung injury and mortality. Am J Pathol
1996, 149:1963-1970.
25. ... are key regulators of alveolar
formation, they have also been implicated in abnormal lung
remodeling that results in fibrosis and changes in the
Commentary
Growth factors...
Báo cáo y học: " MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle? " pps
... MAPK
kinases (MKKs), which largely determine the balance of MAPK
activation in response to inflammatory stimuli [8,9].
The second interesting observation by Goertz and colleagues
is the inability ... N-terminal kinase is required for met-
alloproteinase expression and joint destruction in inflamma-
tory arthritis. J Clin Invest 2001, 108:73-81.
3. Mengshol JA, Vincenti MP, Coon CI, Ba...
Báo cáo y học: "Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis" pps
... family inhibit both MyD88 and TRIF
pathways by induction of suppressor of cytokine signalling
(SOCS)-1 and -3 [83-85]. In light of these links between TKs
and TLR signalling, the recently discovered ... ability to interact with
phosphatidylinositol-4,5-bisphosphate [42] (Figure 1).
Evidence obtained in murine and human models indicate the
involvement of the MyD88-dependent sig...
Báo cáo y học: "TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways" pdf
... neutrophil
sequestration and lung injury induced by endotoxin and hyperinflation.
Crit Care Med 2010, 38(1):194-201.
66. Tremblay LN, Slutsky AS: Ventilator-induced lung injury: from the bench
to the bedside. Intensive ... development of HDM-driven allergic airway
inflammation and the production of Th2 cytokines by
mediastinal lymph node T cells. Interestingly, in the same
mice,...
Báo cáo y học: " Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice" ppt
... assayed by zymography, and net gelatinase
activity in BALF assayed by digestion of fluorescein cou-
pled gelatin, as previously described [12]. Densitometry
of zymography gels was done using ... cause
of increased risk of lung infections in children and adults.
Smoke exposure is linked in adults to an increased inci-
dence and severity of asthma, impaired lung function and
a...
Báo cáo y học: " Matrix metalloproteinases in lung biology" ppsx
... examined and does not influ-
ence matrilysin expression in other cell types, namely
macrophages, fibroblasts, and keratinocytes.
The widespread production of matrilysin in conducting
airway epithelium ... demonstrate that matrilysin is induced
by injury and is prominently expressed by migrating epithe-
lial cells. Although we do not yet know what process or
factor induces matrilysin...
Báo cáo y học: "Genetic polymorphisms in lung disease: bandwagon or breakthrough?" ppt
... study has enhanced features, including
reducing phenotypic heterogeneity by focusing on the
decline of lung function rather than COPD and by compar-
ing extreme phenotypes. From 5887 male and ... a poly-
morphism and disease exists can be greatly improved by
studying a more narrowly defined intermediate phenotype.
In the case of asthma, intermediate phenotypes include
total IgE and...
Báo cáo y học: "Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study" ppsx
... baseline, change in weight, change in BMI
between surveys and years since quitting. Predictors in
each model are shown in the footnote to table 3. Baseline
lung function parameters were included in ... of
packs smoked and were not examined separately in the Six
Cities study [6].
In both men and women, mean packs smoked per day
between 1991 and 2002 were linearly associ...
Báo cáo y học: " Regional coordination in medical emergencies and major incidents; plan, execute and teach"
... within the command and con-
trol centre (Figure 1 and 2).
A system with a duty officer (RTiB) (RN, specialized in
emergency care combined with further training in disaster
medicine as well as in ... be included in the risk
assessment regarding possible major incidents in this
region. The purpose of this study was to find whether this
institution has achieved its primary tasks by...