Báo cáo y học: "Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity" potx

... Access Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity Qian Wu 1 , Qingrui ... suggested that interferon-lambda 1 (IFN-l1), a type III interferon, plays an immunomodulatory role. In this study we investigated its role in SLE, in...

Ngày tải lên: 12/08/2014, 15:23

... autoimmune inflammatory de- myelinating disease of the central nervous system (CNS) that is a leading cause of disability in young adults. Autonomic dysfunction is commonly seen in patients with ... critical pathways of autonomic nervous system, including the brain stem, spinal cord, hypothalamus and cerebral cortex. Demyelinating plaques may disrupt reflex pathways in the...

Ngày tải lên: 26/10/2012, 09:39

... lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b. J Clin Invest 1997, 100:604-612. 5. Coclet-Ninin J, Dayer JM, Burger D: Interferon-beta not only inhibits interleukin-1beta ... of the study agent), includ- ing flu-like symptoms occurring after the injections. The adverse events occurred with similar frequency in patients receiving IFN-β-1a and those receiving place...

Ngày tải lên: 09/08/2014, 01:23

... Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Function Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; ESR, erythrocyte ... line; low disease activity) or >6 mg/l (thin line; increased disease activity). AS, ankylosing spondylitis; ASAS, Assessments in Ankylosing Spondylitis [working group]; BASDAI, Bath An...

Ngày tải lên: 09/08/2014, 06:22

... into remission, low disease activity, moderate disease activity and high disease activity [7]. Interestingly, the cut-off criteria for the DAS28 that were found in this way were only slightly ... Ferraccioli GF: Discriminative ability of com- posite indices for measuring disease activity in rheumatoid arthritis: a comparison of the Chronic Arthritis Systemic index, Disease Act...

Ngày tải lên: 09/08/2014, 07:20

... [10] recently reported increased MIF levels and a correlation with the disease activity in patients with systemic lupus erythematosus. Recent findings suggest that MIF might participate in the pathogenesis ... primary patients with Sjögren's syn- drome (pSS) with normal γ-globulins and with hypergammaglobulinemia. Figure 2 IL-10-secreting peripheral blood...

Ngày tải lên: 09/08/2014, 10:20

... in ankylosing spondylitis. Introduction Ankylosing spondylitis (AS) is a frequent chronic inflammatory rheumatic disease that already affects the axial skeleton at a young age [1], starting in ... of patients with and without spinal inflammation with respect to the development of future syn- desmophytes were found. This may also be explained by the relatively small number of pati...

Ngày tải lên: 09/08/2014, 13:21

... score in FFI pain of -14 points and a mean change score in FFI disability of -8 points. The only study reporting MICs for the FFI has been per- formed in patients with plantar fasciitis following ... RA-rela ted pain) a reduction of one point in NRS pain represented a MIC [36]. The NRS change score in our study may therefore be interpreted as a clinically relevant reduction in...

Ngày tải lên: 10/08/2014, 21:24

... level dur- ing the night is maintained by continuous secretion. Circadin ® is prolonged-release melatonin and is approved as a drug in Europe for primary insomnia in patients aged 55 years or above. ... melatonin is helpful in stop- ping the long-term use of benzodiazepines in patients with schizophrenia - the SMART trial. Melatonin Melatonin is a naturally occurring hormone p...

Ngày tải lên: 11/08/2014, 16:20

... the type of interaction may depend on th e chronol- ogy of contamination with the two viruses: HCV super- infection in previously HBV infected patients, co-infec- tion or HBV infection in HCV ... between individuals with single HBV infection and HCV/HBV co-infected patients revealed significantly lower viremia levels in the second group than in the first one (Figure 1A). These...

Ngày tải lên: 12/08/2014, 01:21