Báo cáo y học: "Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice" docx
Báo cáo y học: "Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice" docx
... rheumatoid arthritis. Mol Ther 2003, 8:707-717.
17. Nishida K, Komiyama T, Miyazawa S, Shen ZN, Furumatsu T, Doi H,
Yoshida A, Yamana J, Yamamura M, Ninomiya Y, Inoue H, Asahara H:
Histone deacetylase ... 13:R77
http:/ /arthritis- research.com/content/13/3/R77
Page 4 of 11
RESEARC H ARTIC L E Open Access
Histone deacetylase inhibition alters dendritic
cells to assume a t...
Báo cáo y học: "Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis" doc
... 16 h at 45°C. The arrays were washed and
stained in the Affymetrix Fluidics Station 400 and scanned
using the Hewlett-Packard GeneArray Scanner G250 0A.
Microarray data analysis
The image data were ... Sox17 antisense, 5'-AATGTCGGGGTAGTT-
GCAATA-3'; Brachyury sense, 5'-
GCGAGCTGGGTGGATGTAGA-3'; Brachyury antisense, 5'-
CAAGGCGGCACAAGACTAAGTC-3; Mash1 sense, 5&a...
Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt
... 1
Histone deacetylase inhibitors block cartilage glycosaminoglycan and collagen loss induced by IL-1α/OSMHistone deacetylase inhibitors block cartilage glycosaminoglycan and
collagen loss induced by ... day 14. Glycosaminoglycan (GAG) release is
shown as at day 7 and was assayed using the dimethylmethylene blue
method. Collagen release is shown as at day 14 and was measured
us...
Báo cáo y học: " Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils" docx
... possible anti-inflammatory effects of
HDAC inhibitors on granulocytes, recent in vivo data in
animals suggest that HDAC inhibitors may have poten-
tial to act as anti-inflammatory agents. Choi and ... Changes
in histone acetylation patterns have been reported in
many human diseases, particularly cancer, and investiga-
tors have used HDAC inhibitors against many malignan-
cies. H...
Báo cáo y học: "Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice" pptx
... suppress transcription and reduce inflammator y cyto-
kines in models of autoimmune and inflammatory dis-
eases [7,8]. Butyrate, a HDAC inhibit or, is a short-chain
fatty acid derived from bacterial ... administration of butyrate
was applied orally not intranasally. Butyrate is an anti-
tumor agent, so it is cytotoxi c. Therefore, the intranasal
delivery of butyrate may be harmful...
Báo cáo y học: "Antisense oligonucleotide inhibition of Heat Shock Protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats" ppt
... Medicine, 1-1 Idaigaoka-Hasamamachi-Yufu City-
Oita 879-5593, Japan
Email: Satoshi Hagiwara* - saku@med.oita-u.ac.jp; Hideo Iwasaka - hiwasaka@med.oita-u.ac.jp; Shigekiyo Matsumoto - SIGEKIYO@med.oita-
u.ac.jp; ... pulmonary fibrosis in rats
Satoshi Hagiwara*, Hideo Iwasaka, Shigekiyo Matsumoto and
Takayuki Noguchi
Address: Department of Brain and Nerve Science, Anesthesiology, Oita Un...
Báo cáo y học: " Mode of inhibition of HIV-1 Integrase by a C-terminal " docx
... hypothesis by measuring the affinity of mAb33 to
HIV-1 IN proteins that contain Ala substitutions in each of
these positions. To gain additional insight into the mode
of inhibition by mAb33 and ... Bujacz G, Alexandratos J, Wlodawer A, Merkel G, Andrake M, Katz
RA, Skalka AM: Binding of different divalent cations to the
active site of avian sarcoma virus integrase and their e...
Báo cáo y học: "Phosphodiesterase 4 inhibition but not beta-adrenergic stimulation suppresses tumor necrosis factor-alpha release in peripheral blood mononuclear cells in septic shock" ppt
... have
expected reduced anti-inflammatory efficacy of rolipram in
PBMCs of septic patients. Conversely, in our study,
unchanged AC expression and maintained anti-inflammatory
efficacy of rolipram ... previously [18].
Statistics
Data were calculated as mean ± standard error of the mean
and were analyzed using one-way analysis of variance. If vari-
ances differed significantly, the Mann-W...
Báo cáo y học: "Histone modifications: from genome-wide maps to functional insights" ppsx
... analysis of histone-modifying
enzymes. Such studies of histone deacetylases (HDACs) and
histone acetyltransferases (HATs) in yeast argue that acety-
lation of most histone lysine residues is in ... 21 and 22 are also H3K9K14-acetylated.
Virtually no variation was found in H3 density, suggesting
that in human cells differences in nucleosome occupancy are
minor, and thus are u...
Báo cáo y học: "Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans"
... product containing bitter orange extract, caffeine and green tea
extract does not lead to increased cardiovascular stress and that fat oxidation may increase in
certain populations.
Key words: ... 764-773
21. Smedema JP, Muller GJ. Coronary spasm and thrombosis in a
bodybuilder using a nutritional supplement containing
synephrine, octopamine, tyramine and caffeine. So...