Báo cáo y học: "Identification of new autoantibody specifici

Báo cáo y học: "Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor b pathway in patients with systemic sclerosis" pot

... intensity by IgG from SSc patients were analysed by using Pathway Studio soft- ware. Interestingly, most of these proteins were involved in the transforming growth factor b (TGF -b) pathway (Additional ... this article as: Bussone et al.: Identification of new autoantibody specificities directed ...

Ngày tải lên : 12/08/2014, 15:23

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Báo cáo y học: "Identification of possible candidate genes regulating Sjögren''''s syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy" docx

... several of the RI lines, thereby retaining the phenotype of parental C57BL/6.NOD-Aec1Aec2 mice, while a number of the RI lines also failed to show a loss of secretory activities, thereby indicating ... balance of IL-6 and transforming growth factor- beta influenced by retinoic acid. Thus, the intricacy and bala...

Ngày tải lên : 09/08/2014, 13:22

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Báo cáo y học: "Identification of an endogenous retroviral envelope gene with fusogenic activity and placenta-specific expression in the rabbit: a new "syncytin" in a third order of mammals" ppt

... and the cellular cytotro- phoblasts, the labeling profile is compatible with syncytin- Ory1 being expressed in the cytotrophoblast just before fusion takes place and/or in the newly formed syncytio- trophoblast ... transduced with syncytin-Ory1. Finally, in situ hybridization of rabbit placenta sections with a syncytin-Ory1 probe r...

Ngày tải lên : 12/08/2014, 23:22

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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"

... clinical history, and certain laboratory data may guide the choice of which endoscopic in - vestigation to perform first in patients with IDA, thereby, potentially reducing the frequency of ... endoscopic investigation to perform first in patients with IDA (especially in pre-menopausal women), thereby, potentially redu...

Ngày tải lên : 25/10/2012, 11:18

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Báo cáo y học: "Identification of Cellular Membrane Proteins Interacting with Hepatitis B Surface Antigen using Yeast Split-Ubiquitin System"

... prey protein interacts with the bait protein, this would bind the NubG and Cub domains together to form the ubiquitin complex. This complex will then be recognized by UBPs and the TF that ... system is not suitable for the analysis of interaction between membrane bound proteins. The split-ubiquitin yeast two hybrid system has be...

Ngày tải lên : 02/11/2012, 11:08

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Báo cáo y học: "Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers" docx

... indicating that the subpopulations – although exhibiting considerable overlap – are not absolutely identical. The expression of triple com- binations of MPC typical surface markers, combined with the ... were incubated with 10 ng/ml recom- binant human transforming growth factor- β 3 (Tebu, Offenbach, Germany) during chondrogenesis....

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx

... no inhibiting effect of the SmD3 peptide on the binding of anti- Sm antibodies to the native Sm antigen in ELISA (Varelisa ® Sm; data not shown). The absence of inhibition can be explained by the ... peptide synthesis, non- specific binding sites were blocked by overnight incubation of the membranes in blocki...

Ngày tải lên : 09/08/2014, 06:22

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Báo cáo y học: "Identification of kinectin as a novel Behçet''''s disease autoantigen" doc

... of the kinesin-binding domain is very probably the most conservative form of kinectin; it does not bind kinesin but act as a membrane anchor for the transla- tion elongation factor- 1 delta in the ... that are large coiled- coil rich proteins (≥100 kDa) in the cytoplasm. Conclusion Here we report the detection...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc

... cell lysates were extensively deiminated in vitro. This is demonstrated by the uniform migration of deiminated enolase at a pI of 5 and by the replacement of arginine by citrulline in all the peptides ... although the intensity of the staining indicated that levels of citrullination were relatively low...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis" pdf

... is frequently seen in the joints of patients with RA [27,29], indicating that the gene expression profiles obtained from these RA models well represent those of patients with RA. In addi- tion, many of ... alternative pathway of the complement system. This pathway is also critical in K/BxN mice, another animal...

Ngày tải lên : 09/08/2014, 08:22

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