Báo cáo y học: "Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers" doc

... Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers. Arthritis Research & Therapy 2011 ... Access Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negati...

Ngày tải lên: 12/08/2014, 15:23

... New York; 2000. Figure 3 Correlation between MBL genotype group and MBL serum levelsCorrelation between MBL genotype group and MBL serum levels. Pre- operative (pre-OP) mannan -binding lectin (MBL) ... value. Mannan -binding lectin (MBL) is a central part of the innate immune system. It belongs to a group of proteins called col- lectins. Its structure enables multiple...

Ngày tải lên: 12/08/2014, 22:22

... AS101 in our experimental system may be mediated by in hibition of two steps in the NFB pathway by modifying specific cysteine residues in IKKa and in the p50-subunit resulting in the inhibition ... DNA -binding abilities in the iNOS promoter. Furthermore, the secre- tion of the inflammator y cytoki ne IL-6, regulated by the NFkB pathway, was significantly inhibited by AS101...

Ngày tải lên: 11/08/2014, 08:22

... decline and respiratory diseases are associated with proximity to roads with heavy traffic, traffic density or exposure to traf- fic-related air pollution [12-15]. The majority of these studies investigated ... sources already had decreased whereas traffic-related pollution was increasing. Women are probably more susceptible for COPD and respiratory symptoms caused by environmen-...

Ngày tải lên: 12/08/2014, 18:20

... Subsequently, intermediately decreased MBL serum levels are seen in individuals with the genotypes XA/XA and YA/O, whereas very low or undetectable serum MBL levels are seen in individuals with genotypes ... antibody positivity, were not associated with MBL2 genotypes. Conclusion Genetically determined MBL deficiency does not increase susceptibility to JRA...

Ngày tải lên: 09/08/2014, 10:23

... C4 levels were quantified by using an immunodiffusion technique. Immunoglobulin E in serum was quantified by nephelometry and mannose -binding lectin by time-resolved fluorometry. Mannose -binding ... alternative pathway relies on interference by foreign substances in a delicate activation-inhibition balance and the third pathway, the mannan -binding lectin (MBL) or lectin...

Ngày tải lên: 10/08/2014, 23:22

... galactosylation of IgG and simultaneously increased MBL levels can be observed, with the latter being strictly related to maternal MBL genotypes. Th erefore, increased MBL levels in concert with increased ... and hyperten- sive disorders in the pregnancies of women with RA. Previously, high MBL levels were associated with less severe disease in RA [1], indicat...

Ngày tải lên: 12/08/2014, 15:22

... upregulated by many factors, including vascular endothelial growth factor (VEGF), erythropoietin, angiopoietin-1, and colony-stimulating factors such as granulocyte–macrophage colony-stimulating factor ... dysfunction in RA. This was certainly seen in the study of Herbrig and colleagues, who studied blood flow in the forearm following infusion of acetylcholine. Vasodilatation was si...

Ngày tải lên: 09/08/2014, 07:20

... Loët X, Working Group for Therapeutic Strategies for Rheumatoid Arthritis: Clinical practice format for choosing a second-line disease modifying anti-rheumatic drug in early rheumatoid arthritis ... define a minimal clinically important improvement and a PASS. The concept of PASS translates the response at the group level (change in mean scores) into clinically meaningful inf...

Ngày tải lên: 09/08/2014, 14:22

... further inquiry. Introduction Acute kidney injury (AKI) following cardiac surgery with cardiopulmonary bypass (CPB) can be a devastating complication associated with high morbidity, mortality and ... three strata of injury were defined as: i) RISK - serum creatinine increase ×1.5 baseline or urine output <0.5 ml/kg/hour × 6 hours, ii) INJURY - serum creatinine increase ×2.0 or...

Ngày tải lên: 10/08/2014, 09:22