Báo cáo y học: "Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers" doc
... Mannan Binding Lectin (MBL)
genotypes coding for high MBL serum levels are associated with
rheumatoid factor negative rheumatoid arthritis in never smokers.
Arthritis Research & Therapy 2011 ... Access
Mannan Binding Lectin (MBL) genotypes coding
for high MBL serum levels are associated with
rheumatoid factor negati...
... New York; 2000.
Figure 3
Correlation between MBL genotype group and MBL serum levelsCorrelation between MBL genotype group and MBL serum levels. Pre-
operative (pre-OP) mannan -binding lectin (MBL) ... value.
Mannan -binding lectin (MBL) is a central part of the innate
immune system. It belongs to a group of proteins called col-
lectins. Its structure enables multiple...
... AS101 in our experimental system
may be mediated by in hibition of two steps in the NFB
pathway by modifying specific cysteine residues in IKKa
and in the p50-subunit resulting in the inhibition ... DNA -binding
abilities in the iNOS promoter. Furthermore, the secre-
tion of the inflammator y cytoki ne IL-6, regulated by the
NFkB pathway, was significantly inhibited by AS101...
... decline
and respiratory diseases are associated with proximity to
roads with heavy traffic, traffic density or exposure to traf-
fic-related air pollution [12-15]. The majority of these
studies investigated ... sources
already had decreased whereas traffic-related pollution
was increasing. Women are probably more susceptible for
COPD and respiratory symptoms caused by environmen-...
... Subsequently, intermediately decreased
MBL serum levels are seen in individuals with the genotypes
XA/XA and YA/O, whereas very low or undetectable serum
MBL levels are seen in individuals with genotypes ... antibody positivity, were
not associated with MBL2 genotypes.
Conclusion Genetically determined MBL deficiency does not
increase susceptibility to JRA...
... C4 levels were quantified by using an immunodiffusion technique.
Immunoglobulin E in serum was quantified by nephelometry and mannose -binding lectin by time-resolved
fluorometry. Mannose -binding ... alternative pathway
relies on interference by foreign substances in a delicate
activation-inhibition balance and the third pathway, the
mannan -binding lectin (MBL) or lectin...
... galactosylation of IgG and simultaneously increased MBL
levels can be observed, with the latter being strictly related to maternal MBL genotypes. Th erefore, increased MBL
levels in concert with increased ... and hyperten-
sive disorders in the pregnancies of women with RA.
Previously, high MBL levels were associated with less
severe disease in RA [1], indicat...
... upregulated by
many factors, including vascular endothelial growth factor (VEGF),
erythropoietin, angiopoietin-1, and colony-stimulating factors such as
granulocyte–macrophage colony-stimulating factor ... dysfunction in RA. This
was certainly seen in the study of Herbrig and colleagues,
who studied blood flow in the forearm following infusion of
acetylcholine. Vasodilatation was si...
... Loët X, Working Group for Therapeutic Strategies for
Rheumatoid Arthritis: Clinical practice format for choosing a
second-line disease modifying anti-rheumatic drug in early
rheumatoid arthritis ... define a minimal clinically
important improvement and a PASS. The concept of PASS
translates the response at the group level (change in mean
scores) into clinically meaningful inf...
... further inquiry.
Introduction
Acute kidney injury (AKI) following cardiac surgery with
cardiopulmonary bypass (CPB) can be a devastating
complication associated with high morbidity, mortality
and ... three strata of injury
were defined as: i) RISK - serum creatinine increase ×1.5
baseline or urine output <0.5 ml/kg/hour × 6 hours, ii)
INJURY - serum creatinine increase ×2.0 or...