Báo cáo y học: "Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis" docx

... regarding PTPN22 +1858C/ T polymorphism and PsA have produced conflicting results. In a study by Hinks et al., no association was found between PsA and PTPN22 +185 8C/T in a patient population from the ... regression analysis (P = 0.017). There was no association between dactylitis and deformed joints and, no other significant associations between the ca rriage of th...

Ngày tải lên: 12/08/2014, 15:22

... of the study and to the interpretation of the results. LP had the main responsibility for the genetic analyses and contributed to the analysis and interpretation of the results. LA and LK were ... of the manuscript. CB contributed to the design of the study, to the collection of the data, to statis- tical analysis and to the writing of the manuscript. IL...

Ngày tải lên: 09/08/2014, 07:20

... allele to the risk for development of the disease is unknown and prob- ably modest. The problem is further complicated by the fact that many of these alleles interact with other genes in the back- ground ... case-control study conducted in the Swedish population [17] failed to rep- licate the association between RA and the TNFRII 196M/R polymorphism. That study revealed...

Ngày tải lên: 09/08/2014, 06:23

... investigated the relationship between the VDR polymorphisms and diseases. The effect of VDR polymorphisms in renal failure has been explored, and Sezer et al. demonstrated that the BsmI polymorphism ... an association between bone mass and polymorphisms of the recognition sites of the restriction enzymes BsmI and ApaI in the 3'-end of the VDR gene, an...

Ngày tải lên: 08/08/2014, 16:23

Ngày tải lên: 12/08/2014, 19:22

... transmembrane glycoprotein that is mainly expressed by T-lymphocytes, monocytes/macrophages and dendritic cells. The CD4 receptor normally functions as a coligand and coreceptor of the major histocompati- bility ... [3-5]. The equilibrium established between these different forms may vary according to the cell type, the activation state of the cell and the redox conditio...

Ngày tải lên: 13/08/2014, 09:20

... to determine the association between the circulating sCD40L levels and m ortality, and the secondary objec- tive to determine the association between circulating sCD40L, inflammatory and prothrombotic ... its association with sCD40L levels. There are been reported an association between sCD40L levels and severity of acute coronary artery syndrome [31] and between tro...

Ngày tải lên: 14/08/2014, 08:21

... parameters and the presence and severity of meniscal tears. The potential effect of Table 3 Association between foot rotation during early and late stance and the presence and severity of meniscal ... morphology and the genesis of knee OA and pain [8-11]. The peak external knee adduction moment, which is generated by the combination of the ground reaction force p...

Ngày tải lên: 09/08/2014, 10:23

... days; record two—100 mg/30 days, 200 mg/30 days), we summed the daily dose and divided by the number of records and summed the days-supply (e.g. 300 mg/60 days). Using these decision rules, we ... days, daily dose was summed to the maximum days-supply between the 2 prescriptions. b. If the days-supply between prescriptions was greater than 14 days, dose was considered...

Ngày tải lên: 11/08/2014, 16:21

... with the more frequent -28C, suggesting that the polymorphism can increase RANTES expres- sion in the human body [12]. Therefore, it’s reason- able to hypothesize that the RANTES -28C/G poly- morphism ... asthma severity [29]. Therefore, as one of the C-C chemokines, the RANTES polymorphisms necessarily resulted into the level of eosinophils elevating correspond, and the...

Ngày tải lên: 26/10/2012, 09:39