Báo cáo y học: "Antinuclear antibodies in healthy people: the tip of autoimmunity’s iceberg? David S Pisetsky1,2" pot

... with diseases such as systemic lupus erythematosus, ANA expression occurs commonly in healthy people. The basis for this expression is unknown, although it may re ect features of the assays for ... implicated in a predisposition to diseases Abstract Antinuclear antibodies (ANAs) are venerable biomarkers for assessing the diagnosis and prognosis of patients with autoimm...

Ngày tải lên: 12/08/2014, 15:22

... indivi- duals from s outh Indian populations were included in the analyses. After sample size normalization, we mea- sured genetic diversity using various summary statistics, including the number of segregating ... diversity measurements are in flu- enced by sample size, we normalized the sample size of each group by randomly selecting a subset of HapMap individ uals to matc...

Ngày tải lên: 09/08/2014, 22:23

... determination of BMLs was assessed using 60 randomly selected knee MRIs (κ value 0.88, P < 0.001). Statistical analyses The descriptive statistics of the characteristics of study partic- ipants were ... be statistically significant. All analy- ses were performed using the SPSS statistical package (standard version 15.0.0; SPSS Inc., Cary, NC, USA). Results Two hundred ninety-se...

Ngày tải lên: 09/08/2014, 14:20

... viruses in 150 of the 164 sample collected in the first year (91.5%) and 512 of the 565 samples col- lected in the second year (90.6%) were subtyped and analysed using pyrosequencing. Subtype ... analysis; AL supported in the laboratory assays. All authors read and approved the final manuscript. Acknowledgements This study was supported in part by MedImmune, and in...

Ngày tải lên: 12/08/2014, 04:20

... apoptosis progresses rapidly in vitro, and (c) that apoptosis of the trophoblasts in the tissue was suppressed by the presence of a low concentration of glucocorticoids, hydrocortisone and cortisone ... gradually during pregnancy. The stress may serve as a signal to initiate and propagate the in ammatory process and result in apoptosis of placental tissues. Accordingl...

Ngày tải lên: 22/02/2014, 07:20

... for the diagnosis, prevention, and treatment of osteoporosis in asthmatic patients receiving inhaled corticosteroid therapy. Diagnosis of Osteoporosis Bone densitometry by dual-energy x-ray absorp- tiometry ... loss. 2,3,10,11 In patients who are already at risk because of established glucocorticoid-induced osteoporosis, bisphos- phonates have the capacity to restore bone mass a...

Ngày tải lên: 08/08/2014, 20:23

... that these effects may not only contribute to the increased risk of infection 2 but may also be implicated in the increased rates of other forms of chronic inflammatory respiratory disease seen in ... observations in the context of the emerging hypothesis that variations in TLR function in early life may be implicated in allergic propensity. There is now growing ev...

Ngày tải lên: 08/08/2014, 21:20

... of 10 these indices and subscales. The correlations among the psychometric scales (PANSS, YMRS and the MADRS) and individual items and subscales of the SCCT revealed some very interesting points ... errors of omission and commission were registered for this test. The psychometric assessment The psychometric assessment included Positive and Negative Symptoms Scale (PANSS) [15...

Ngày tải lên: 09/08/2014, 01:21

... Women s Hospital, Boston, Massachusetts, USA 2 Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA 3 Harvard Medical School, Boston, Massachusetts, USA 4 Department of ... 1478-6362) Abstract Accelerated atherosclerotic vascular disease (ASVD) is a major cause of death in systemic lupus erythematosus (SLE). Although many authorities are calling for aggr...

Ngày tải lên: 09/08/2014, 01:22

... face-to-face in a clinical setting or in a telephone interview format by trained outcome assessors. Eight functional categories are assessed specifically by the HAQ: dressing and grooming, arising, eating, ... two other longitudinal studies going on in our center: the University of Pennsylvania Alumni study [12] and Stanford University Staff used as controls in the Stanford Ru...

Ngày tải lên: 09/08/2014, 01:24