Báo cáo y học: "Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model" pptx

... inflammation and bone erosion in Mmp8- deficient mice To quantify joint invo lvement, we assessed synovial inflammation and bone erosion in hematoxylin and eosin stained sections of ankle joints, and ... no inflammation; 1 = slight thickening of synovial cell layer and/ or some inflammatory cells in the sublin- ing; 2 = thickening of synovi al li ning and mod...

Ngày tải lên: 12/08/2014, 15:22

... the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2) and inducible Figure 1 Cytokine circulating levels in mice at the end of treatment in the collagen-induced arthritis ... described in this report, VIP treatment greatly reduces the local expression of both these cytokines in the joints of arthritic mice, which may account for the blo...

Ngày tải lên: 09/08/2014, 06:23

... xenoestrogens in the ovaries of ArKO mice in vivo. Estrogen plays an important role not only in the reproductive system but also in the regulation of bone metabolism to maintain bone mass. In the present ... (Fig. 6A). In pQCT analysis, the distincttrabecular bone could be detected visually, seen as red and yellow, in wild-type mice, but the trabeculae disapp...

Ngày tải lên: 24/03/2014, 03:21

... Park in the USA, arguably the world’s first, was established in 1872, fol- lowed in 1879 by the Royal National Park in Australia south of S ydney and the Rocky Mountain National Park in Canada in ... implemented yet and whether there was any functioning system of co-man- agement”. This is exactly the point: there is and there is not, depending on yo ur viewpoint. A...

Ngày tải lên: 10/08/2014, 09:21

... considered; thepresenceofobesity,diabetes, whether the person was a current smoker and whether the individual was currently being treated for hypertension or hypercholes- terolaemia. Obesity was defined ... differences in any of the baseline characteristics between the exploratory and confirmato ry samples. Table 3 shows Models 1, 2, 3 and 4 of the multivariate analysis gene...

Ngày tải lên: 11/08/2014, 15:22

... measured by increasing the FiO 2 as a function of the EELV obtained decreasing FiO 2 . The EELV obtained increasing the FiO 2 was -56 + 1.0078 multiplied by the EELV obtained decreasing the FiO 2 (r 2 = ... 0.0001). (b) The Bland-Altman plot of the EELV measurement obtained increasing the FiO 2 and the EELV obtained decreasing the FiO 2 . The x axis shows the mean...

Ngày tải lên: 13/08/2014, 16:20

... 3 Commentary Intravascular thrombosis plays a fundamental role in the pathophysiology of cardiac arrest. Autopsy results from cases of unsuccessful resuscitation and coronary angio- graphy in survivors ... underlying acute myocardial infarction or pulmonary embolism. Therefore, thrombolysis during cardiopulmonary resuscitation may improve survival. Methods Objective: To determi...

Ngày tải lên: 13/08/2014, 20:21

... endopeptidase activity GO:0004220:cysteine-type peptidase activity KOG1282:lysosomal cathepsin A KOG1543:Cysteine proteinase Cathepsin L GO:0003796:lysozyme activity Stress_Down w/ Bt toxin,Cry5B_Huffman2004 Stress_Down ... death KOG1339:aspartyl protease Insulin_Down in Dauer_McElwee2004 Insulin_Down in daf-2 _McElwee2004 Insulin Down in daf-2 Murphy2003 Insulin_Up in Dauer_McElwee20...

Ngày tải lên: 14/08/2014, 08:20

... enzymes. Detailed in vivo investigationsperformed during the course of storage starch synthesis show that amylopectin and amylose synthesis are partly disconnected and that amylose synthesis persists when the ... amylose continues to accumulate at the final stage of starch synthesis in the absence of concomitant amylopectin synthesis (reviewed in [41]). In vitro synthesis o...

Ngày tải lên: 22/02/2014, 07:20

... hydrolyse them; they were then dried to remove the water and HCl. The pellets were converted into the corresponding D -(+)-2-octylglyco- side acetate by the method of Leontein et al. [30]. The ... report on the GDP-6-deoxy- D -talose biosynthetic pathway and the role of GDP-4-keto-6-deoxy- D -mannose reductase in the synthesis of GDP-6-deoxy- D -talose. Keywords: Actinob...

Ngày tải lên: 17/03/2014, 10:20