Báo cáo y học: " Pathogenic effect of interleukin-17A in induction of Sjögren’s syndrome-like disease using adenovirus-mediated gene transfer" docx

... Access Pathogenic effect of interleukin-17A in induction of Sjögren’s syndrome-like disease using adenovirus-mediated gene transfer Cuong Q Nguyen 1,2,3,4* , Hongen Yin 5 , Byung Ha Lee 3 , Wendy ... article as: Nguyen et al.: Pathogenic effect of interleukin-17A in induction of Sjögren’s syndrome-like disease using adenovirus- mediated gene t...

Ngày tải lên: 12/08/2014, 15:22

... expectancy, thymic involution, and antigen exposures, the development of CD4 + CD25 + T R cells may occur in the periphery in man. Induction of CD4 + CD25 + T R cells in the periphery The induction of ... capable of directly generating Tr1 cells in vitro and in vivo, and may represent a naturally occurring dendritic cell subset involved in eliciting tolerance in vivo...

Ngày tải lên: 09/08/2014, 01:24

... against looking at each step of the programme independently for example paying attention to individual variables such as number of women who received counseling, of those who received counseling ... shortcomings and the need for this is further highlighted by the findings of this study. The limitations of this study were that the data was only collected from the women's point...

Ngày tải lên: 10/08/2014, 05:20

... circulating fatty acid concentrations caused by insulin resistance and increased adipocyte lipolysis plays a pivotal role in the development of this syndrome [1,8]. CIDE-A (cell-death-inducing DFF45-like ... Corresponding author Abstract Background: Increased levels of circulating fatty acids caused by insulin resistance and increased adipocyte lipolysis can accumulate within the liver...

Ngày tải lên: 13/08/2014, 13:20

... rate of loss of BMD, the risk of osteoporosis and the risk of fractures [14-20]. Many studies on the effect of inhaled CSareconfoundedbydifficulties in quantifying the varying and of ten intermittent ... view of bone thinni ng and osteoporosis occurring largely as a result of CS use is simplistic. Our findings could be interpreted as indicating a disease specific compone...

Ngày tải lên: 12/08/2014, 13:22

... dyssynchrony during dobutamine stress in patients with wide QRS duration (20). In contrast, Kurita et al. reported on an increased mechanical dyssynchrony during pacing–induced tachycardia in ... increase in intra-LV dyssynchrony was also demonstrated during pharmacological stress in systolic heart failure patients with normal QRS dura- tion. The prevalence of dyssynchrony w...

Ngày tải lên: 05/11/2012, 11:32

... mpor- tance of Arg97 and Arg108 in the activity of CYP2C9, especially for substrate binding, by site-directed mutagenesis and homology modelling. The phenotypical abnormality of hypertension was examined ... USA). The standard procedure of p rotein modelling using COMPOSER includes the following steps: (a) determination of an initial set of topologically equivalent r esidues b...

Ngày tải lên: 24/03/2014, 03:21

... double-blind, placebo-controlled efficacy and safety study of quetiapine or lithium as monotherapy for mania in bipolar disorder. J Clin Psychiatry 2005, 66:111-121. 66. McElroy SL, Martens BE, Winstanley ... Tran P, Breier A: A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitat...

Ngày tải lên: 09/08/2014, 01:21

... is expressed by a variety of cell types involved in RA, including activated T cells and synoviocytes [8]. These cells, in the pres- ence of cytokines like TNFα and macrophage colony stimulat- ing factor, ... RT-PCR of the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2) and inducible Figure 1 Cytokine circulating levels in mice at the end of tre...

Ngày tải lên: 09/08/2014, 06:23

... activity by intra-articular injection of RNODN. These results suggest the inhibitory effect of RNODN on the induction and activity of osteoclasts. Direct intra-articular injection of RNODN into ... osteoclast induction and activity in vitro and in vivo Yasuo Kunugiza 1,2 , Tetsuya Tomita 2 , Naruya Tomita 3 , Ryuichi Morishita 1 and Hideki Yoshikawa 2 1 Division of Clini...

Ngày tải lên: 09/08/2014, 08:22