Báo cáo y học: "Time course of airway remodelling after an acute chlorine gas exposure in mice" pdf

... airway remodelling after an acute chlorine gas exposure in mice Stephanie A Tuck 1 , David Ramos-Barbón 2 , Holly Campbell 1 , Toby McGovern 1 , Harry Karmouty-Quintana 1 and James G Martin* 1 Address: ... reported an increase, albeit transient, in ASM quantity in rats after acute exposure to Cl 2 gas. The signals involved in repair and in the repopulatio...

Ngày tải lên: 12/08/2014, 15:21

... XiangMing Fang 1 1 Department of Anesthesiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, QingChun Road, Hangzhou 310003, PR China 2 Key Laboratory of Multiple Organ ... possibly by virtue of its ability to counteract the pathophysiological consequences of actin release during trauma, injury and infection [11-14]. In animal models of sepsis, deplet...

Ngày tải lên: 13/08/2014, 11:22

... -80°C, and analyzed in a blinded fashion. Quantification of circulating angiopoietin-1 and 2, and soluble Tie2 Ang-1 and Ang-2 were measured by in- house immuno lumino- metric assay (ILMA), and ELISA ... permeability and is considered a key molecule in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) [3,4]. Ang-1 and Ang-2 are antagonist...

Ngày tải lên: 13/08/2014, 16:20

... changes were associated with an early and transient increase in eNOS and an early and profound increase in iNOS expression, while expression of nNOS remained unchanged. Both 3-NT, a marker of ... Health and the American Physio- logical Society for the care and use of laboratory animals. Animal model The ovine model of ALI and sepsis induced by smoke inhalation and instillati...

Ngày tải lên: 13/08/2014, 21:20

... Chief of this journal. Author details 1 Department of Upper Gastrointestinal Surgery, Hyogo College of Medicine, 1-1, Mukogawa-machi, Nishinomiya City, Hyogo, 663-8501, Japan. 2 Department of Gastrointestinal ... Correspondence: mtake@hyo-med.ac.jp 1 Department of Upper Gastrointestinal Surgery, Hyogo College of Medicine, 1-1, Mukogawa-machi, Nishinomiya City, Hyogo, 663-8501, Jap...

Ngày tải lên: 10/08/2014, 09:22

... com- pressing and is frequently located in the hand. All the patients were initially treated with carbamazepin, amitriptyline, gabapentin, some antidepressants and sym- patholytic agents, and antipsychotic ... important to keep in mind that high-velocity and fragmentary agents like grenades and land-mines fre- quently cause nerve injury at several levels. Manual mus- cle testing began by...

Ngày tải lên: 10/08/2014, 10:20

... highlights an unusual presentation and managem ent of retropharyngeal abscess. The presence of gas- forming organisms in this clinical scenario makes it an interesting case. Physicians should maintain ... E, Ben-Yehuda Y, Roth Y: Oropharyngeal injuries in children. Pediatr Emerg Care 2007, 23:914-918. 9. Gray RF, Hawthorne M: Disease of the mouth and pharynx. In Synopsis o...

Ngày tải lên: 11/08/2014, 00:23

... were consented. In vitro half-life of xylitol in human airway epitheliaFigure 1 In vitro half-life of xylitol in human airway epithelia. Panel A. Transmission electron micrograph of perfluorocar- bon/OsO4 ... gm/kg/hr [17]. After intravenous use, the half-life of xylitol is about 20 minutes in humans [18]. Exogenous xylitol is rapidly oxidized in the liver by NAD-li...

Ngày tải lên: 12/08/2014, 16:20

... ts, and mainly granulocytes are the sources of more than 90% of circu- lating VEGF-A [30]. In contrast, in an animal model of sepsis VEGF-A levels increased in liver, kidney and heart, and no difference ... a future and planned validating study [31], as well as to gain insights about the time -course of sFlt-1 and VEGF- A release during the very initial phase of sepsis. Alv...

Ngày tải lên: 18/06/2014, 19:20

... ts, and mainly granulocytes are the sources of more than 90% of circu- lating VEGF-A [30]. In contrast, in an animal model of sepsis VEGF-A levels increased in liver, kidney and heart, and no difference ... 1 day (range 0-2 days). Eight patients died from complications of sepsis within the first 30 days after the onset of fever, yielding an overall 30-day mortality of...

Ngày tải lên: 20/06/2014, 03:20