Báo cáo y học: "Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals" potx
Báo cáo y học: "Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals" potx
... purposes)
Respiratory Research
Open Access
Research
Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency
individuals
Caroline S Sandström
1
, Natalia Novoradovskaya
2
, Corrado M Cilio
3
,
Eeva Piitulainen
4
, ... study is the first to show higher levels of plasma sCD14 and monocyte mCD14
expression in young, clinically healthy PiZZ AAT subjects.
Background
CD14 is a mu...
Báo cáo hóa học: " Endotoxin and CD14 in the progression of biliary atresia" ppt
... endo-
toxin clearance [15,34]. During cholestasis, the accumu-
lation of endotoxin may induce hepatocyte injury and
impair CD14 synthesis during late-stage BA.
Although studies of liver injury should ... paraformaldehyde and embedded in paraf-
fin for immunohistochemical analysis.
Determination of sCD14 levels by ELISA
The sCD14 levels of plasma were determined using a
commercially availa...
Báo cáo y học: "Antigen receptor signaling in the rheumatic diseases" doc
... signaling which dephosphorylates the inhibitory
tyrosine of Lck [54]. Pep cooperatively inhibits TCR signaling
by binding Csk and this association in turn is mediated by a
proline-rich sequence in ... ζ chains that contain varying
numbers of immunoreceptor tyrosine-based activating motifs
(ITAMs). The dual tyrosines of ITAMs are phosphorylated by
the Src family kinases (SFKs), which, in...
Báo cáo y học: "TAM receptor ligands in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus." ppsx
... 48% amino acid identity to pro-
tein S, was discovered in the early 1990 s [15]. It con-
tains an N-terminal g-carboxyglutamic acid (Gla)
domain, interacting wit h phosphatidylserine containing
membranes, ... the immune system by
receptor tyrosine kinases of the Tyro 3 family. Science 2001, 293:306-311.
49. O’Donnell K, Harkes IC, Dougherty L, Wicks IP: Expression of receptor
tyrosine k...
Báo cáo y học: "Role of CD14 in lung inflammation and infection" pptx
... tuberculosis remains to be established.
In addition to its role in (myco)bacterial infections,
CD14 may also play a role in the pulmonary host
response against respiratory syncytial virus (RSV), ... by sCD14)) (mortality)
S. pneumoniae mouse CD14
-/-
clearance (reversed by sCD14), neutrophil in ux, cytokines, 41
chemokines ( dissemination (reversed by sCD14))
(mo...
Báo cáo y học: " Clinical review: Fever in intensive care unit patients" potx
... No 3 Ryan and Levy
The goal of the present review is to question, by critically
evaluating the literature, the practice of routinely treating fever
in the ICU patient. The pathophysiology of fever ... mortality, had less organ damage,
and had less evidence of acute lung injury.
Interestingly, severe sepsis may be associated with a dimin-
ished heat shock response. Lymphocytes obtained from...
Báo cáo y học: "Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 1" doc
... Beck-
Nielsen H: Cytokines and bone loss in a 5-year longitudinal
study — hormone replacement therapy suppresses serum
soluble interleukin-6 receptor and increases interleukin-1-
receptor antagonist: ... entry into the study and after 12 and
24 months, using vaginal ultrasonography and cytology. E
2
in serum was measured (approximately 12 hours after
tablet intake) by radioimmunoassay...
Báo cáo y học: "Enhanced osteoclast development in collagen-induced arthritis γ in interferon-γ receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis" docx
... Haematoxylin staining on paraffin sections of the joints on day 27 after immunisation, showing bone erosion and
multinucleated giant cells in IFN-γR KO mice (arrows in (c) and detail in inset). ... cells migrate into the joints before
differentiation into osteoclasts. Interestingly, levels of
calcitonin receptor mRNA were higher in IFN-γR KO than
in wild-type mice, confirming the...
Báo cáo y học: "Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population" docx
... population
Sheng-Yu Jin
*1
, Seung-Jae Hong
*2
, Hyung In Yang
3
, Sang-do Park
3
, Myung-Chul Yoo
4
,
Hee Jae Lee
1
, Mee-Suk Hong
1
, Hae-Jeong Park
1
, Seo Hyun Yoon
1
, Bum-Shik Kim
1
, Sung-
Vin Yim
1
, ... haplotype may be associated with primary knee OA, and
genetic variations in the ER-α gene may be involved in OA.
Keywords: estrogen receptor, haplotype, knee osteoarthritis, p...
Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt
... as well as entry into acute and chronic inflammatory
sites. Expression of chemokines and chemokine receptors in
the RA synovial tissue has been extensively analyzed, and
chemokines are thought ... However, the role of chemokines specifically on B
cells in RA has not been completely delineated.
In this study, we examined chemokine receptor expression by
peripheral blood in both norma...
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