Báo cáo y học: " Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B" pps

... purposes) NTHi-induced COX-2 and PGE2 expression mediated by p38 MAPK and NF-kappa B signaling pathway To determine the role of NTHi-induced p38 MAPK and NF-kappa B activations in NTHi-induced COX-2 and PGE2 ... the inhibition of p38 MAPK. Conclusion: NTHi induces COX-2 and PGE2 expression in a p38 MAPK and NF-kappa B-dependent manne...

Ngày tải lên: 12/08/2014, 15:21

... local production of inflammatory cytokines and chemokines in T cells. However, little is known about induction of these genes by HTLV-I infection in lung epithelial cells. Results: We tested infection of lung ... significance of aberrant production of inflammatory cytokines and chemokines in the lung has been given increasing attention and a variety of cytok...

Ngày tải lên: 13/08/2014, 05:21

... only ATRA inhibited IL-1-induced IL-6 expression in rat synovial fibroblasts by inhibiting ERK 1/2 pathway and subsequent activation of AP-1 and NF-IL-6 independently of RAR. Introduction Retinoids ... suppresses interleukin-6 expression in interleukin-1-stimulated synovial fibroblasts by inhibition of ERK 1/2 pathway independently of RAR activation Mélanie Kirchme...

Ngày tải lên: 09/08/2014, 01:22

... cells within rheumatoid synovium and in synovial fluid CD4 + CD3 + T cellsIL-17 expression on T cells within rheumatoid synovium and in synovial fluid CD4 + CD3 + T cells. (a) Rheumatoid synovial ... survival any further. Using an inhibitor of the phosphatidylinositol-3-kinase signal- ling pathway (Ly294002) and an inhibitor of the NF-κB path- way (Bay11-7085), we found...

Ngày tải lên: 09/08/2014, 10:23

... Xu L, Datta SK: Hyperexpres- sion of cyclooxygenase 2 in the lupus immune system and effect of cyclooxygenase 2 inhibitor diet therapy in a murine model of systemic lupus erythematosus. Arthritis ... B cells in lupus. Apigenin also causes apoptosis of hyperactive lupus APCs and T and B cells, probably by inhibiting expression of NF- B-regulated anti-apoptotic molec...

Ngày tải lên: 09/08/2014, 14:20

... findings suggest the induction of TIARP in CD11b + cells in splenocytes of arthritic mice, especially during the early phase of the disease. Localization of TIARP protein in proliferative synovium Next, ... days 7 and 8, peaked in severity on day 14, and then gradually subsided. High expression levels of TIARP mRNA and proteins were detected in splenocytes on day...

Ngày tải lên: 09/08/2014, 14:22

... Allergology and Clinical Immunology: Skin tests used in type I allergy testing Position paper. Sub-Com- mittee on Skin Tests of the European Academy of Allergol- ogy and Clinical Immunology. Allergy ... Sauty A, Winter J, Sperisen P, Aubert J-D, Spertinin F: Induction of tumour necrosis alpha and inter- leukin-8 gene expression in bronchial epithelial cells by toxic scho...

Ngày tải lên: 12/08/2014, 16:20

... S, Nagano Y, Bloom ET, Domae N: Co-stimulation of T cells with CD2 augments TCR-CD3-mediated activation of protein tyrosine kinase p72syk, resulting in increased tyrosine phosphorylation of adapter proteins, ... student in STS lab and helped in the compiling and analysis of the data presented in the manuscript. AEM helped in the analysis of the data and editing...

Ngày tải lên: 13/08/2014, 01:20

... of plants lacking lutein due to the multiple effects of zeaxanthin in photoprotection, including ROS scavenging and direct quenching of Chl fluorescence by binding to the L2 allosteric site of Lhc ... lutein, violaxanthin and zeaxanthin can bind to sites L1 and L2 of Lhc proteins [18,33] while the site for neoxanthin binding is site N1. This was recently confirmed by X-ray c...

Ngày tải lên: 12/08/2014, 05:20