... haplotype of three polymorphisms was asso-ciated with OA. We conducted further analysis of OATable 4Comparison of estrogen receptor- α gene polymorphisms in subtypes of osteoarthritis patients ... haplotype may be associated with primary knee OA, andgenetic variations in the ER-α gene may be involved in OA.Keywords: estrogen receptor, haplotype, knee osteoarthritis, polymorphismIntroductionOsteoarthritis ... Korea3Division of Rheumatology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea4Department of Orthopedic Surgery, College of Medicine, Kyung Hee University, Seoul,...