Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx
Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx
... contributes to pulmonary injury, resulting in a variety of pulmonarypathologies. Based on the rodent model of chronic aspira-tion described herein, chronic aspiration can initiate aninflammatory response ... pathogenesis of chronic aspira-tion-associated disease. In the current study, histologyCytokine response to chronic aspiration of gastric fluidFigure 7Cytokine response to chronic aspiration of gastric ... pulmonary inflammatory response thatresults from chronic aspiration. Repetitive aspiration events can initiate an inflammatory response consisting of macrophages and T cells that is associated...
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Báo cáo y học: " Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using modelbased approaches" ppt
... each of the comparators included in this analysis. The most striking feature of the plot isthat the response to indacaterol at the plateau exceeds the response of all comparators. In other words, ... 1) an integrated analysis of study-level data, and 2) an integrated analysis of patient-level data. The objectives of both a nalyses were to pro-vide a precise quantitative characterization of ... variability on Emaxandwas analysed using a Bayesian methodology.As the summary data used in this analysis are con-trasts to placebo, the model was constrained t o have a null response with placebo...
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Báo cáo y học: "CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan–polysaccharide complexes of Gram-positive bacterial cell walls" docx
... these findings, CD14 knockout mice hadsignificantly inhibited inflammatory cell infiltration and synovialhyperplasia, and reduced expression of inflammatory cytokines in PG-PS arthritic joints. ... randomly.Histologic analysisFollowing the intravenous PG-PS injection on day 0, micewere killed on the next day after the joint inflammation hadreached a peak (usually, on day 4). The hind ... Olsen JC, Watson JM, Mondal K, Rine-hart C, Haskill JS: NF-kappa B as a target for anti-inflammatorygene therapy: suppression of inflammatory responses in monocytic and stromal cells by stable gene...
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Báo cáo y học: "Intussusception of the small bowel secondary to malignant metastases in two 80-year-old people: a case series" potx
... [6]. In a simple abdom-inal radiograph the findings are not disease-specific, and in the radiological examination with barium (providedthat the state of health of the patient allows it) the char-acteristic ... the remaining 50% the causes are primary tumor metastases to the gastrointestinal tract, especially melanoma whichhas two predominant forms in the intestine. The mostcommon form is that of multiple ... bibliographical data. SPwrote the final manuscript. AP performed the histologic examination onboth cases. TG is the Head of the Department. All authors have read andapproved the final manuscript.Competing...
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Báo cáo y học: "Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China" pps
... or factor II in the Taiwanesestudy [14]. C ombining the factor II and factor III items in the present study is similar to those of factor II in the European study. The items of factor II in the ... study and that carried out in Taiwan wereChinese. In the European and Taiwanese studies, the duration criterion for hypomania was two days but in thepresentstudyitwasaminimumoffourdays .The ratio ... were initially retained and clinical con-siderations decided the final number of factors. The internal consistency of the HCL-32 was determinedusing Cronbach’s alpha. Spearman correlation analysiswas...
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báo cáo hóa học: " Wallerian degeneration: the innate-immune response to traumatic nerve injury" potx
... myelinating Schwann cells enwrap intact axons and further express normally the inflammatory cytokines TNFa and IL- 1a mRNAs and the TNFa protein. Traumatic injury at a distant site in the far left (not ... functions are regulated by the interplayand balance between a ctivating and inhibitory signals;neither acts in an “all or none” fashion. Inhibition maybe produced by a family of immune inhibitory ... days after the injury. They thenbecome amenable for scavenging by activated Galectin-3/MAC-2 expressing macrophages and Schwann cells; the onset of clearance is 3 to 4 days after the injury...
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Báo cáo Y học: Characterization of the exopolysaccharide produced by Streptococcus thermophilus 8S containing an open chain nononic acid doc
... and NMRanalyses of the oligosaccharide obtained from the polysac-charide by de-N-acetylation followed by deamination andreduction demonstrated the ÔheptaÕsaccharide repeating unit to be: in ... The Asn-linked carbohydrate chains of human Tamm-Horsfall glycoprotein of one male; novel sulfatedand novel N-acetylgalactosamine-containing N-linked carbohy-drate chains. Eur. J. Biochem. 209, ... acid-2¢-yl) -a- D-glucopyra-nose (Sug, vide infra). Furthermore, a characteristic signal atd 2.057 was observed, originating from the N-acetyl group of GalpNAc.De-N-acetylation and deamination of the nativepolysaccharideOwing...
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Báo cáo Y học: Characterization of the 105-kDa molecular chaperone Identification, biochemical properties, and localization pptx
... brain.We have investigated the localization and developmentalinduction of the protein in the rat brain. In the immuno-histochemical analysis, the protein was mainly detected in the cytoplasm of the ... proteinappeared at approximately the age of 5 weeks and coincidedwith the appearance of spermatozoa during the development of the rat testis. The 105-kDa protein was more abundant in the spermatozoa ... with the 105-kDa protein (APG-1/OSP94) the same as HSP90 in rat testis and brain.Expression time of 105-kDa protein in rat brain In order to clarify the localization of the 105-kDa protein in the...
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Báo cáo Y học: Characterization of the active site of histidine ammonia-lyase from Pseudomonas putida pptx
... AG,Marburg, Germany).Enzyme assay and protein determinationHAL activity was measured spectrophotometrically at 25 8Cfollowing the formation of trans-urocanate at 277 nm. The assay was performed in 1-cm ... (reviewed in [1]). An analogous mechanismwas proposed for the reaction catalysed by the homologousenzyme phenylalanine ammonia-lyase (PAL, EC 4.3.1.5)which convertsL-phenylalanine into trans-cinnamic ... coordinatingwater O , imidazolyl-N1 of the histidine, Asn195coordinating water O , NH31 of histidine, and S atom of the sulfate anion , carboxylate C of histidine. Afterdocking, the sulfate...
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Báo cáo Y học: Characterization of the self-splicing products of two complex Naegleria LSU rDNA group I introns containing homing endonuclease genes pdf
... (5¢-AATTAATACGACTCACTATAGGTCCTGCACACCTTGT-3¢)/O P461 (5¢-CGCCAGACTAGAGTCA-3¢), OP454 (5¢-AATTAATACGACTCACTATAGGCGGATAAGGCCAAT-3)/OP451 (5¢-GCTCACGTTCCCTGT-3¢), and OP452 (5¢-AATTAATA CGACTCACT ATAGGAACTTACAAAGGCTA-3¢)/ ... Whereas the I-PpoI RNA harbours no polyadenylationsignal and seems not to be polyadenylated in vivo [14], bothNaegleria introns contain the AAUAAA consensus poly-adenylation signal located exactly ... I-Na eI has a motif similar to the antiparallel b sheetDNA binding domain found in I-PpoI. Whereas almost a llHis-Cys homing endonucleases have two zinc coordinationdomains, the C-terminal...
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