Báo cáo y học: " Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced " pps

... study was to evaluate the changes in endothelin-1 levels in exhaled breath condensate following intensive exercise in asthmatic patients. Methods: The study was conducted in a group of 19 asthmatic ... asthmatic patients (11 with EIB, 8 without EIB) and 7 healthy volunteers. Changes induced by intensive exercise in the concentrations of endothelin-1 (ET-1) in...

Ngày tải lên: 12/08/2014, 15:21

... China) or matching placebo within 8 hours of the documented time of injury. Qualifying patients were randomly assigned in a 1:1 manner to receive the matching treatment with random numbers. Patients ... standards. Because of the nature of patients& apos; injuries, subjects in this clinical study were incapable of granting informed consent. Investigators therefore obtained...

Ngày tải lên: 13/08/2014, 11:22

... respectively. Binding data was obtained by analytical ultracentrifugation using the direct binding assay as des- cribed in Experimental procedures. Inset: Linearized plot of the binding data for ... possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into relati...

Ngày tải lên: 08/03/2014, 09:20

... made between patients with diffuse mucosal thicken- ing involving the paranasal sinuses (chronic hyperplastic rhinosinusitis) but without polypo- sis and those patients with diffuse sinonasal polyposis with ... disease process is occurring. The typical findings with allergic fungal sinusitis include polypoid mucosa and tenacious allergic mucin with abundant eosinophils and e...

Ngày tải lên: 08/08/2014, 20:23

... provided new insights into how OA may be successfully managed. The symptoms of osteoarthritis: pain and instability The pain of OA is activity-related, with pain coming on generally only when a person ... only symptom of OA experienced by patients with knee and hip OA. They also frequently experience a sensation of instability or buckling. The most common symptom is one of shi...

Ngày tải lên: 09/08/2014, 01:22

... ultimately, of the upregulation of proinflammatory cyto- kines [19,20]. By whichever means they themselves become activated, they induce a plethora of inflammatory products, including degradative enzymes, ... correlate with joint damage [10,21] indirectly link joint damage to the inflammatory cytokine levels. However, as indicated before, the correlation of CRP with joint destruct...

Ngày tải lên: 09/08/2014, 01:22

... of peptidyl arginine deiminase (PADI) activity appears also to be involved in the maintenance of immunological tolerance to antigens. Thus, citrullination of proteins in RA patients may unmask ... to citrullinated peptides in RA patients. Further studies [23,24] focussed on an involvement of peptidylarginine deiminases citrullinating enzymes (encoded by PADI genes). In a Ja...

Ngày tải lên: 09/08/2014, 06:22

... transfection or DNA-binding proteins [11,12]. Within the context of SLE, these findings suggest that molecules inducing autoimmunity have intrinsic immunologic activity and may serve as adjuvants ... Furthermore, immune complexes of ANAs can drive the production of proinflammatory cytokines, inducing the ‘interferon signature’, and intensifying disease. Together, these findings point to...

Ngày tải lên: 09/08/2014, 11:20

... hypertrophy and hyperplasia, with an increased number of lining cells, often accompanied by infiltration of the sublining tissue with scattered foci of lymphocytes [68]. Synovitis is often localized ... or inhibitors of inflammatory cytokines. Degeneration of articular cartilage in osteoarthritis: inflammation The role played by inflammatory cytokines and mediators produced by...

Ngày tải lên: 09/08/2014, 14:20

... osteocalcin) increasing from baseline levels within a few weeks of therapy. This is followed by a slower increase in levels of bone resorption markers (CTX and C-telopeptide crosslink of type I ... deterioration. In RA, the pro- inflammatory cytokine TNF-α is critical in driving inflammatory disease. TNF is mainly produced by macrophages, fibroblasts and dendritic cells, and in...

Ngày tải lên: 09/08/2014, 14:20