Báo cáo y học: " In vitro metabolism of beclomethasone dipropionate, budesonide, ciclesonide, and fluticasone propionate in human lung precision-cut tissue slices" doc

... purposes) Discussion Several pharmacokinetic and pharmacodynamic parame- ters, including bioavailability, receptor binding-affinity, and elimination half-life contribute to the safety and effi- cacy profile of an ICS. ... metabolism of four ICS. Donor profiles are summa- rized in Table 1. Cellular viability Viability of tissue samples was assessed using ATP content and pro...

Ngày tải lên: 12/08/2014, 15:21

... N-terminus of m5C-DNA methyltransferase Msp I is involved in its topoisomerase activity Sanjoy K. Bhattacharya* and Ashok K. Dubey† Department of Biochemical Engineering and Biotechnology, Indian Institute ... binding; methyltransferase MspI; proteolysis; topoisomerase I. Methylation of DNA at C-5 of cytosine has been implicated in a number of biological processes in proka...

Ngày tải lên: 24/03/2014, 00:21

... 4-hydroxylase and pro- collagen lysyl-hydroxylase [45-47]. Through these actions, HIF1α affects the rate of synthesis of procollagen chains in vivo and in vitro [48]. HIF2α is closely related ... Dako), rinsed in distilled water and incu- bated in fast-DAB (3,3'-diaminobenzidine) peroxidase substrate (Sigma) for 5 minutes and counterstained in diluted filtered hae...

Ngày tải lên: 09/08/2014, 10:20

... the emergency department with acute abdominal pain, nau- sea and vomiting and a two month history of intermit- tent lower abdominal pain. There was no history o f previous abdominal surgery, smoking ... be an inflammatory fibroid polyp. Conclusion: Although inflammatory fibroid polyps are rare and benign, in the case of intestinal obstruction the only solution is a surgical approa...

Ngày tải lên: 11/08/2014, 03:21

... abdomen pain and a two month history of intermittent cramping and lower abdominal pain. Computed tomography imaging demonstrated a partial intestinal obstruction in the location of the terminal ileum. ... Histopathologic examination showed the mass to be an inflammatory fibroid polyp. Conclusion: Although inflammatory fibroid polyps are rare and benign, in the case of intestin...

Ngày tải lên: 11/08/2014, 07:20

... cohort inclusion if they: i) reported difficulty in the last three months with each of the fol- lowing: stair climbing, rising from a chair, standing and walking; ii) swelling, pain or stiffness in ... [47,48] since, in the setting of painful OA, improved treatment of depression may reduce not only depressive symptoms, but also arthritis pain, activity limitations, and overall...

Ngày tải lên: 11/08/2014, 15:22

... Hering LM, Oosthuizen PP: The revolving door phenomenon in psychiatry: comparing low- frequency and high-frequency users of psychiatric inpatient services in a developing country. Soc Psychiatry ... outcomes. Modified assertive interventions that focus on m aintaining adherence and offering additional support may not only reduce inpatient days but also improve psychopathology in p...

Ngày tải lên: 11/08/2014, 16:22

... load in HIV-1 and HIV- 2 singly and dually infected individuals in Guinea-Bissau, West Africa: significantly lower plasma virus set point in HIV-2 infection than in HIV-1 infection. Arch Intern ... sensitiv- ity of e xisting genotypic rules and bioinformatic tools have to be increased before they can be used in a clini- cal setting. Next , we examined the coreceptor phenotyp...

Ngày tải lên: 12/08/2014, 23:23

... controlled trial of school- based humanistic counselling for emotional distress in young people: Feasi- bility study and preliminary indications of efficacy Child and Adolescent Psy- chiatry and Mental ... Ireland and in secondary schools in Wales; and a policy commitment to providing access to school counselling to all pupils in Scotland by 2015 [4]. In contrast to sc...

Ngày tải lên: 13/08/2014, 18:21

... concentrations of the BCAAs valine, leucine and isoleucine and the AAAs phenylalanine and tyrosine[21]: BCAA AAA ratio valine leucine isoleucine phenyla / [][ ][ ] [ = ++ llanine tyrosine][ ] . + The ... delivery, and unidirectional cerebral influx of phenylalanine increased, whereas the cerebral influx of leucine and isoleucine were abolished, and a cerebral glutamine efflu...

Ngày tải lên: 13/08/2014, 20:21