Báo cáo y học: "Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema" pptx
Báo cáo y học: "Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema" pptx
...
T lymphocytes, the lasts having increased
cytotoxic activity. Because systemic inflammation is also a component of emphysema, we
hypothesize that peripheral CD8
+
T lymphocytes of emphysematous ... studies
have described their state of activation and their cytotoxic
potential in the peripheral blood. Perforin, granzyme B,
and FasL are cytotoxic molecules used by CD8...
Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... endoscopy in outpatients with iron defi-
ciency anemia. The aim of our study was to investi-
gate the incidence of GI pathological findings in
symptomatic and asymptomatic patients with IDA
and to ...
3
Platelets,
4
C reactive protein,
5
Erythrocyte sedimentation rate,
6
Carcinoembryonic antigen
86 patients underwent upper gastrointestinal
tract endoscopies and 62 pati...
Báo cáo y học: "Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specime" pot
... Considering that infiltrating T cells in the rheumatoid
synovium in the early stage of RA are predominantly T helper
type 1 cells [8], our findings that the degree of lymphoid cell
infiltration ... joints
by targeted biopsy under arthroscopy, and specimens from
long-standing RA were obtained by total knee arthroplasty at
the Center for Rheumatic Disease, Matsuyama Red Cross
Hosp...
Báo cáo y học: "Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritsi" potx
... assistance in interpretation of the data and draft-
ing the manuscript. MR designed the study and provided
assistance in analysis and interpretation of the data and draft-
ing the manuscript.
Acknowledgements
This ... therapeu-
tic potential in arthritis.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
CB performed the R...
Báo cáo y học: " Arthritis, osteomyelitis, septicemia and meningitis caused by Klebsiella in a low-birth-weight newborn: a case report" pps
... a therapeutic option with good outcomes in
patients with serious infections with resistant strains of
K. pneumoniae, even in neonates and infants.
Consent
Written informed consent was obtained ... predisposing factors, including prematurity, intravenous catheter,
history of antibiotic therapy and intravenous nutrients.
Case presentation: A low-birth-weight, 33-day-old Caucasian girl w...
Báo cáo y học: " Mucocele-like tumor and columnar cell hyperplasia of the breast occurring in a morphologic continuum" pptx
... proliferations, including intraductal carcinoma,
invasive carcinoma, atypical ductal hyperplasia and
hyperplasia of the usual type [2-4]. Most invasive carcino-
mas that arise in this setting are of the ... epithelial atypia displayed slightly higher
proliferative activity. The low proliferative activity in
columnar cell lesions noted in this case is compatible with
data reported in...
Báo cáo y học: " RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1" pdf
... -
CAGCCTGTTGCCTCTGTGAGA-3 ’ (forward) and
5’ -GGCAGCT CCTTGTTTACTCC-3’ (reverse);
and CD70, 5’-GGGCGTCTACTTGCTTCA-3’ (forward)
and 5’-CCTGCATCCTGGCAACTGC-3’ (reverse).
Real-time quantitative polymerase chain ... CD4
+
T cells and healthy controls, con-
sistent with the mRNA levels detected by real-time PCR
reported in our previous study [21]. Interestingly, our
ChIP experiments...
Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx
... antioxidant N-acetyl-
L
-cysteine (NAC) provides cysteine that feeds into
the biosynthetic machinery, allowing the formation of glutathione (GSH) by the action of the rate-limiting enzyme, γ-glutamylcysteine ... pull NF-κB off DNA, and export NF-κB back to
its resting state in the cytoplasm. Thick lines indicate the activating
pathway; thin lines indicate the inactivating pathway.
....
Báo cáo y học: " Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A" potx
... the
manufacturer's instructions. The effectiveness of siRNA
against specific targets was determined by RPA and immu-
noblotting.
Competing interests
The authors declare that they have no competing interests.
Authors' ... eIF5A matura-
tion by inhibiting the interaction between DOHH and its
substrate, deoxyhypusyl-eIF5A. At clinically used concen-
trations, the drugs profound...
Báo cáo y học: " MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes" ppsx
... [42].
Consequently, these microRNAs may contribute to trans-
formation of HTLV-1-infected cells, i.e., the pathogenesis
of ATLL, by either maintaining differentiation status or
actively driving cells towards ... constitutes an important facet in both
viruses' efforts to establish perstistence or their potential
to bring about malignant transformation. In contrast to
activation by...