... lipid-freeapolipoproteins and may underlie the general propensity of apolipoproteins to form amyloid in vivo [7]. The ability of apoC -II to form amyloid in vitro can be compared to in vivoamyloid formation involving ... an inhibitory effect of clusterin on amyloid formation by Ab, and a fragment of the prion protein [26,27]. In thisinvestigation, we explore the effect of clusterin on amyloidformation by apoC -II and ... formation involving many of the exchangeableapolipoproteins, including apoA-I [8,9], apoA -II [10,11],apoA-IV [12], apoE [13], and apolipoprotein–like proteins,a-synuclein [14] and serum amyloid A...