Báo cáo y học: "Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection" doc

... reduction in Influenza A and avian Influenza titres after 1 min exposure to a pH 3.5 nasal gel spray composition in solu-tion test versus a phosphate buffered saline controlFigure 2 Log reduction in Influenza ... whether a low pH intranasal spray could be effective against influ- enza virus, initially using in vitro solution tests to deter- mine susceptibility of v...

Ngày tải lên: 12/08/2014, 15:20

... change. In our in vitro study, we showed that IL-23 induced key cytokines such as IL-17 and IFN-γ and that IL-23 induced human osteoclastogenesis via these cytokines (Figure 9). Our findings indicate ... down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein- induced autoimmune encephalomyelitis. J Immunol 1996, 157:3223-3227. 33. Park H,...

Ngày tải lên: 09/08/2014, 10:21

... Stanley S, Fauci AS: Interleukin 6 induces human immu- nodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional ... cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells. J Rheumatol 1993, 20:803-808. 8. Pol...

Ngày tải lên: 13/08/2014, 09:20

... (the aminoglycoside, kanamycin, the a minocyclitol glycoside, streptomycin, t he penicillins, ampicillin and penicillin G, the aminocyclitol, spectinomycin, tetracycline and Cl-tetracycline, and ... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity intro...

Ngày tải lên: 21/02/2014, 15:20

... two different erythrocyte age/density fractions obtained by isopycnic centrifugation on a Percoll gradient. Methyl esterification in intact erythrocytes was assayed by incubating them in the presence ... only with erythrocyte ageing, but also with intrinsic defects of erythrocytes [7]. In fact, L -isoaspartate, a major protein fatigue degradation product, is increased in hereditary sphe...

Ngày tải lên: 08/03/2014, 22:20

... Papay P: Physical symp- toms in post-traumatic stress disorder. J Psychosom Res 1994, 38:715-726. 37. Joseph S, Andrews B, Williams R, Yule W: Crisis support and psy- chiatric symptomatology in ... therefore measures mainly psychological and psychosocial symptoms spread across five subscales meas- uring anxiety, feeling incompetent, depression, social dys- function, and coping failu...

Ngày tải lên: 08/08/2014, 23:21

... (on cell lining and endothe- lial cells), Tie1 (on lining cells, macrophages, smooth muscle cells, lymphocytes and fibroblasts) and Tie2 (on lining cells, macrophages, endothelial cells and vascular smooth ... mRNA and protein expression in RA is not consistent with these findings and this may be due to the fact that the inflammatory milieu in RA synovial tissue is far more co...

Ngày tải lên: 09/08/2014, 03:24

... MCCS, physical functioning was assessed by asking five questions: Did health problems limit you in your everyday physical activity? Did pain interfere with your normal work? Has your physical ... born in Australia, and this difference could not be explained merely by factors such as education level, physical functioning, and weight. Although access to health care may play a role, it m...

Ngày tải lên: 09/08/2014, 14:21

... data in bioinformatics and computational biology solutions using R and Bioconductor. In Bioinformatics and Computational Biology Solutions Using R and Bioconductor. Edited by: Gentleman R, Carey ... design and interpretation of the study and contributed to manuscript writing. HP participated in the design and coordination of the study. AB conceived the study and particip...

Ngày tải lên: 09/08/2014, 22:23

... predominantly in the primary tumor genome before initiation of metastasis [9]. In line with this hypothesis is the finding that distinct clonal cell populations in primary pancreatic carcinoma ... genomes, yielding important insights into the genes and mechanisms that contribute to cancer development and progression [5, 6]. Systematic sequence analysis of coding regions in pri...

Ngày tải lên: 09/08/2014, 23:20