Báo cáo y học: " Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice" pptx

... purposes) Rapamycin reverses hypoxia-induced thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 6 Rapamycin reverses hypoxia-induced thickening of the right ventricular ... purposes) Rapamycin attenuates hypoxia-triggered thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 4 Rapam...

Ngày tải lên: 12/08/2014, 15:20

... find- ings in the lung in vivo, determination of pulmonary function is an essential tool. Existing methods for measur- ing respiratory function in mice in vivo include invasive and noninvasive ... responsiveness (AR) in intact, spontaneously breathing BALB/c mice. Methods: Using noninvasive head-out body plethysmography and the decrease in tidal midexpiratory flow (EF 50 ),...

Ngày tải lên: 12/08/2014, 18:20

... number, and the date of drug dispension. Since January 1 1989 all data from North Jutland County have been stored in a prescription database maintained by the Department of Clinical Epidemiology, ... 30 days before conception and six months post-delivery. In the first analysis, cases were defined as boys with hypospadias recorded in the HDR during the first six months post-de...

Ngày tải lên: 02/11/2012, 10:09

... sites of chymotrypsin. D-Chymotrypsinogen is a chimera constructed to contain a trypsinogen propeptide instead of the Cys1–Cys122-linked wild-type chymotryp- sinogen peptide. D-Chymotrypsinogen also ... of mammalian chymotrypsins and trypsins. The enzyme that was used in this study, rat chymotrypsin B, is highlighted by bold type. The loops are boxed and labelled. Chymotryptic and try...

Ngày tải lên: 22/02/2014, 07:20

... islets and liver of fetal, suckling and adult rats We studied the enzyme activities of two protein complexes involved in the respiratory chain: succinate dehydrogenase (complex II) and cytochrome ... in the c oncentrations of rat live r cyclic AMP and of serum glucose, free fatty acids, insulin, pancreatic and totalglucagoninthemanandintherat.J. Lat. Clin. Med. 82, 957±967. 5. M...

Ngày tải lên: 31/03/2014, 15:20

... on the brain imaging, involving the left insu- lar and anterior temporal cortex, two brain regions fre- quently involved in aphasic syndrome but also in FAS, a cerebrovascular origin must be ... on the brain imaging, involving the left insular and anterior temporal cortex, two brain regions frequently involved in aphasic syndrome but also in FAS, a cerebrovascular origin must be c...

Ngày tải lên: 08/08/2014, 21:20

... subdimensions (that is, hyperactivity and inattention). This finding may reflect the inability to assess the multidimensional atten- tion deficit hyperactivity disorder through only five items different in nature ... cannot stay still for long' and 'I am constantly fidgeting or squirming'. These findings indicated that the aforementioned items create a subdimension within...

Ngày tải lên: 08/08/2014, 23:21

... alter the binding with selectins because the latter bind several glycoproteins [53]. HYA and other GAGs could decrease cytokine gene expression directly [54] or indirectly by binding the CD44 ... Medicine, University of Messina, Messina, Italy 3 Department of Experimental and Clinical Medicine and Pharmacology, School of Medicine, University of Messina, Messina, Italy Corresponding auth...

Ngày tải lên: 09/08/2014, 01:21

... metalloproteinase (MMP) expression and activation in the medium were analysed by gelatin zymography, proteoglycan release by the dimethylmethylene blue assay, and cell viability by the Cytotox 96 ® assay. ... c-fos and c-jun and by proinflammatory cytokines that are known to be involved in arthritic dis- eases [4,5], such as interleukin-1 and tumour necrosis factor α (TNF-α). TN...

Ngày tải lên: 09/08/2014, 01:23

... Phar- macokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res 2000, 20:857- 866. 28. Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, Pando ... per injection per mouse), limited hyperplasia of the intimal lining layer and cell infiltration of the synovial sublining were detected and a decrease in bone erosions was ob...

Ngày tải lên: 09/08/2014, 01:23