Báo cáo y học: " Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis" ppsx
... using gene expression anal- ysis of the airway epithelium of smokers. Apoptosis of airway epithelial cells is relevant to the pathogenesis of chronic bronchitis because disruption of epithelial ... levels by infection with AdPirinFigure 4 Apoptosis in BEAS-2B bronchial epithelial cells following up-regulation of pirin levels by infection with AdPirin. BEAS-...
Ngày tải lên: 12/08/2014, 15:20
... expression as deter- mined by DNA microarrays. This was tested by hybridization of a blotted pulsed-field gel electrophoresis (PFGE) gel with a DHFR probe. Wild-type cells gave rise to two hybridizing bands, ... 70-mer Validation of DNA microarray expression data by qRT-PCRFigure 3 Validation of DNA microarray expression data by qRT-PCR. The mean log10 ratios of select...
Ngày tải lên: 14/08/2014, 20:22
... whereby it i s translocated back to the cytoplasm [19,39]. While NFAT dephosphorylation is mediated by calcineurin, rephosphorylation is catalyzed by a variety of serine kinases, such as glycogen ... activation of T lymphocytes. EMBO J. 9, 4425–4433. 30. Oda, Y. , Kinoshota, M. & Kakehi, K. (1997) Fluorometric assay of binding specificity of plant lectins to yeast cells b...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: " Improvement of platelet dysfunction in chronic myelogenous leukemia following treatment with imatinib: a case report" pps
... reveals that in chronic myelogenous leukaemia (CML) following interferon-α therapy, normalization of megakaryocyte size is associated with the loss of bcr/abl translocation. Histopathology 31:215–221. ... influence of modern targeted therapy on chronic myeloid leukemia -associated platelet disorders. Case presentation: We report the case of a massive hemorrhage in a 32-year...
Ngày tải lên: 10/08/2014, 23:21
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... stability of serum creatinine and platelet counts was associated with significantly increased 28-day mortality. Second, early treatment with DrotAA (within 24 hours of onset of sepsis -associated ... sta- bility is a sign that the patient with severe sepsis may soon begin to improve with the current level of therapy. The concept of a false sense of security due to app...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: " Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization" pdf
... RD, Gobran LI, Rooney SA, Elias JA: Pulmonary type II cell hypertro- phy and pulmonary lipoproteinosis are features of chronic IL-13 exposure. Am J Physiol Lung Cell Mol Physiol 2002, 283:L52-L59. 34. ... analysis of the BAL cytokine profile) or a large volume (5 ml of sterile saline for analysis of the sur- factant protein profile). The amount of liquid retained after BAL was...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration" doc
... respiratory control ratios. This effect was probably mediated by a direct effect of norepinephrine on liver cells. Introduction Septic shock is associated with high mortality, especially when antibiotic ... norepinephrine increases cellular respiration in a dose-dependent manner, and that this effect is blocked by the addition of an α-antago- nist (for example, phenoxybenzamin...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: " Upregulation of Bax and Bcl-2 following prenatal cocaine exposure induces apoptosis in fetal rat brain" doc
... hepatocytes [14]. In addition, we have confirmed that the process of apoptosis defined on the basis of cellular and nuclear chromatin morphology correlates with apoptosis defined on the basis of ... dependently increased activities of caspase-3, caspase-8, and caspase-9 (% of control) in the fetal brain by 177%, 155%, 174%, respectively, at 30 mg/kg/day, and by 191%, 176...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway" ppsx
... metastasis of cancer cells. Migratory cancer cells undergo series of morphological changes by the recon- struction of adhesion and actin cytosk eleton. It is now widely accepted that the process of ... 18:58 http://www.jbiomedsci.com/content/18/1/58 Page 6 of 9 A key element of cell m igration is the regulation of adhesive contacts, which are dynamically assembled and di...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer" ppsx
... al.: Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer. Journal of Hematology & Oncology 2011 4:33. Figure ... Oncology. Journal of Hematology & Oncology 2010, 3:11. 5. Ohrling K, Edler D, Hallström M, Ragnhammar P, Blomgren H: Detection of thymidylate synthase expression in lymph no...
Ngày tải lên: 10/08/2014, 21:23