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Báo cáo khoa học: "Economic Aspects of Disease Monitoring with Special Reference to Bovine Paratuberculosis" pdf

Báo cáo khoa học:

Báo cáo khoa học: "Economic Aspects of Disease Monitoring with Special Reference to Bovine Paratuberculosis" pdf

... 2001Economic Aspects of Disease Monitoring with Special Reference to Bovine ParatuberculosisBy Larry G. PaisleyNational Veterinary Institute, Norway. Present address: Danish Veterinary Laboratory, ... of approxi-mately 5%. However, the herd-level specificitywould be approximately 99.7%Another way to decrease the expected number of false positive reactors would be to decreasethe number of ... median of 70:1. At the as-sumed herd prevalence of 0.2% and a cost/test of 70 NOK the median cost of detecting1 infected herd was approximately 900,000 NOK. If 2 positive reactors were needed to classify...
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Báo cáo khoa học:

Báo cáo khoa học: "Computational structure of generative phonology and its relation to language comprehension." pdf

... degrees of stress to a highly-embedded sentence. The second is to reaxrange the boundaries given by the syn- tax when the intonational phrasing of an utter- ance does not correspond to its ... allowed to vary from language to language. It is possible, however, to postulate the ex- istence of a large, fixed, language-universal set of phonological features and a fixed upper limit to the ... structures that are indendent of the spine (Halle 1985). One page represents the sequence of tones associated with a given articu- lation. By decoupling the representation of tonal sequences from...
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Báo cáo khoa học:

Báo cáo khoa học: " The Methodology off Sememic Analysis with Special Application to the English Preposition" ppt

... ity with WITH 1) WITH 8: with * to talk with pilots friendly with Latin American countries WITH 9: with * filled with milk filled with bad odors Compare this with OF 13. WITH 10: with ... TO 1: to *—— farthest to the right path to one side lands to the east far to the north TO 2: to * (motion) towards come to the edge went to them bring water to dry fields come up to ... wing cockpit of an airplane walls of Troy countries of Asia plains of Pakistan surface of the earth OF 2: of * made of strips of metal coat of fur land of stone rivers of ice called...
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Tài liệu Báo cáo khoa học: Novel aspects of heat shock factors: DNA recognition, chromatin modulation and gene expression ppt

Tài liệu Báo cáo khoa học: Novel aspects of heat shock factors: DNA recognition, chromatin modulation and gene expression ppt

... Ministry of Education,Culture, Sports, Science, and Technology of Japan to H. Sakurai.References1 Fujimoto M & Nakai A (2010) The heat shock factorfamily and adaptation to proteotoxic stress. ... repression of mouse heat shock factor 1.Mol Cell Biol 18, 906–918.13 Newton EM, Knauf U, Green M & Kingston RE(1996) The regulatory domain of human heat shockfactor 1 is sufficient to sense ... histone deacetylases has also been shown inhuman breast cancer cells: treatment of cells with thetransforming factor heregulin leads to increases in thelevels of HSF1 and MTA1 (a component of...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

... feature of chemokines is the redundancy of the system. Several chemokines bind to more thanone receptor, and the majority of chemokine receptorshave multiple ligands, leading to the generation of multiple ... 3¢-untranslatedregion of the SDF-1 gene is associated with the annualrates of radiographic progression, but not with suscep-tibility to RA. However, the functional role of thesevariants has ... as release of mediators of inflammation, cell proliferation andangiogenesis. To date, several animal studies andhuman studies have shown the biological efficacy of specific antagonism of ligands...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of environmental factors pdf

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of environmental factors pdf

... (Institute Of Rheumatology, Rheu-matoid Arthritis)]. We concluded that RA disease activ-ity tends to be negatively associated with the presence of JCP and speculated that patients with JCP have ... chronicinflammatory disease that affects 0.5–1% of the popu-lation and causes progressive joint destruction thatleads to the restriction of activities of daily living anddeterioration of quality of life. ... genetic factors in RA with nationwidestudies of twins with RA, as described previously [1].This minireview focuses on the contribution of envi-ronmental risk factors to the development of RA.InfectionSeveral...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of transcription factors ppt

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of transcription factors ppt

... FEBSMINIREVIEWMolecular aspects of rheumatoid arthritis: role of transcription factorsHiroshi Okamoto1, Thomas P. Cujec2, Hisashi Yamanaka1and Naoyuki Kamatani11 Institute of Rheumatology, Tokyo Women’s ... proliferator-activatedreceptors (PPARs) are such examples. Peroxisomeproliferator-activated receptors are members of thenuclear hormone receptor family, the largest family of transcription factors ... variety of organs and cells. One of the roles of Ca2+is to regulatecalcineurin, which in turn dephosphorylates andinduces the nuclear localization of the cytoplasmiccomponents of nuclear factor...
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Báo cáo khoa học: Functional analysis of disease-causing mutations in human galactokinase potx

Báo cáo khoa học: Functional analysis of disease-causing mutations in human galactokinase potx

... galactokinase in order to see which mechanisticclass it falls into (Fig. 4). a-D-Galactose 1-phosphate wasfound to be an uncompetitive inhibitor with respect to galactose (KIU¼ 28 ± 11 mM) ... the catabolism of galactose. The sugar is phosphor-ylated at position 1 at the expense of ATP. Lack of fullyfunctional galactokinase is one cause of the inherited disease galactosemia, the main ... (out of all the commonmechanisms). If there were either a random mechanism oran ordered one with galactose binding first, galactose-1-phosphate would be a competitive inhibitor with respectto...
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Báo cáo khoa học: Novel aspects of calmodulin target recognition and activation pptx

Báo cáo khoa học: Novel aspects of calmodulin target recognition and activation pptx

... fragments of the K+-channel (c) insertion of CaM between two domains of the anthrax exotoxin (d)binding of Ca2+ions to only one EF-hand pair and (e)binding of CaM in an extended conformation to ... cyclase exotoxinThe crystal structures of the C-terminal fragment (residues291–800) of the exotoxin from Bacillus anthracis,withandwithout its activator calmodulin, is the first structure of aCaM-complex ... of threestructures: (a) exotoxin without CaM (b) exotoxin with CaM and (c) exotoxin with bound CaM and the pseudo-substrate 3¢-dATP.The overall structure of CaM/exotoxin complex is shownin...
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Báo cáo khoa học: Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase pot

Báo cáo khoa học: Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase pot

... changes to the volume of theside-chain that are likely to disrupt the local fold.These two residues, together with N34, are locatedwithin 0.15 nm of each other and all are at, or close to, the ... of UDP-galactose to UDP-glucose was cou-pled to the oxidation of UDP-glucose using the enzymeUDP-glucose dehydrogenase (Sigma; EC 1.1.1.22). Thisresults in the reduction of two molecules of ... susceptible to proteolysis). It is reasonable to predict that if suchpatients were found, their symptoms would be closer to the generalized form than the peripheral form of disease. Some of the mutants...
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