Báo cáo khoa học: "Investigations of Waterborne Pathogens in Eurasian Beaver (Castor fiber) from Telemark County, Southeast Norway" ppt
... regu- larly isolated from river water in Telemark Acta vet. scand. 2001, 42, 479-482. Investigations of Waterborne Pathogens in Eurasian Beaver (Castor fiber) from Telemark County, Southeast Norway By ... knowledge of the contamina- tion routes to water. In Norway, the supply of drinking water to the public and the food indus- try is primarily based on c...
Ngày tải lên: 12/08/2014, 15:20
... bolded; N-terminal residues of the catalytic domain are under- lined. The preregion is indicated in red, the pro-region in black, catalytic domain in blue and the C-terminal domains in violet. The assumed ... cysteine-free subtilisin BPN¢ by introducing disulfide bridges in structurally analogous positions to those in PRK showed no stabilizing effect [33]. However, stabilizing su...
Ngày tải lên: 19/02/2014, 07:20
... can explain the selective loss of S2 dsRNA and increase in L2 dsRNA in cured strains of X. dendrorhous, supporting the hypothesis of the existence of helper/satel- lite virus system in X. dendrorhous. Conclusion The ... similar in S2-cured clones and in wildtype strain. Therefore, the loss of S2 dsRNA in strain UCD 67-385 affect the copy number of L1 but not of L2 ds...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo khoa học: Investigations of the supercoil-selective DNA binding of wild type p53 suggest a novel mechanism for controlling p53 function doc
... p53 DNA-binding domains by oxidation of cysteine residues (to preclude binding within the p53 core domain) and/or by antibodies mapping to epitopes at t he protein C-terminus (to block bindin g within the ... DNA- binding site (CTDBS) is critical for this binding. Here we studied supercoil-selective binding of bacterially expressed full-length p53 using modulation of activity of the p...
Ngày tải lên: 30/03/2014, 15:20
Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... shown that interactions between KCs and endotoxin comprise the initiating event lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies, ... signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein. Drug Metab Dispos 36, 95–101. 10 Ghose R, Guo T & Haque N (2009) Regulation of gene...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels pptx
... absence of cyclophilin D or the presence of cyclosporin A led to a decrease in the extent of uncou- pler-induced depolarization. Accordingly, in substrate-energized mitochon- dria, an increase in ... significant production of P i in the vicinity of the ATPase within the matrix. CYPD ablation or its inhibition by cyclosporin A increases the rate of respiration stimulated by...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... long-chain saturated fatty acids (SFAs) led to increased expression of proin- flammatory cytokines, inhibition of insulin signaling, induction of endoplasmic reticulum (ER) stress, and promotion of ... cell toxicity. These findings are in agreement with previous observations from the Schaffer group, indicating increased incorporation of palmitate (16:0) into the TAG pool only in...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx
... classified as a myrosinase-bind- ing protein-like protein. Myrosinase is a glucosinolate- degrading enzyme [4], and myrosinase-binding protein (MyroBP) has been identified as a component of high-molecular-mass ... binding speci- ficity. In some proteins containing tandem homologous domains, inter-domain interactions fix the relative ori- entation of the domains in a specific multi-domain s...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... subheading and then select the Proteomics link). One of the proteins of interest to the Cell Migration Consortium is paxillin, a scaffolding protein involved in focal adhesions [9]. Shown in Fig. ... shown by solid and dashed lines, respectively. Charge states for the observed ions are speci- fied at the beginning of each line. Coverage from ions of type y¢¢ obtained from a CAD...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
... in skin barrier disruption (Fig. 1A). PPARb mRNA expression was determined in keratinocytes isolated from the epidermal layer of these skins, and was found to be significantly increased in skin ... cultured human keratinocytes [14]. In this study, we examined the interaction between CerK and PPARb, and its role in regulating keratino- cyte survival. We report that in a mouse ke...
Ngày tải lên: 18/02/2014, 18:20