... discovery of leptin as an adipocyte-secreted protein [13]. Systemic analysis of the active genes in WAT, by constructing a 3’-directed complementary DNA library, revealed a high fre-quency of ... prevalence of obesity has increased dramatically in recent years, one of the key targets of public health is obesity and its associated pathological conditions. Obesity occurs as a result of white ... Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. Correspondence to: Hidekuni Inadera, MD and PhD, Department of Public Health, Faculty of...