Báo cáo y học: "Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins" pot
Báo cáo y học: "Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins" pot
... article as: Van Steendam et al., Citrullinated vimentin as an impor-tant antigen in immune complexes from synovial fluid of rheumatoid arthri-tis patients with antibodies against citrullinated ... the antigens from these IC is important to gain more insight into the pathogenesis of RA. Since RA patients have antibodies against citrullinated proteins (ACPA) in their serum and synovial fluid ... prominent citrullinated antigen in IC from SF of ACPA+ RA patients strengthens the hypothesis that citrullinated vimentin plays an important role in the pathogenesis of RA.IntroductionRheumatoid...
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Báo cáo y học: "Shift work as an oxidative stressor" pot
... weight and total plasmaantioxidant capacity. Age and weight were found to be inversely related to total plasma antioxidantcapacity; as age and weight increased, the total plasma antioxidant capacity ... impacts of age and weight were alsoassessed.Results: The total plasma antioxidant capacity was measured in 44 shift-workers with a mean age of 36.57 years (SD: 10.18) and mean BMI of 26.06 ... University of Medical Sciences, Tehran, Iran and 3Private practice, Tehran, IranEmail: Akbar Sharifian* - Sharifians@sina.tums.ac.ir; Saeed Farahani - s.farahani@iranair.com; Parvin Pasalar - pasalar@tums.ac.ir;...
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Báo cáo y học: "Obstructive azoospermia as an unusual complication associated with herniorrhaphy of an omphalocele: a case repor" ppt
... tracts in herniorrhaphy of an omphalocele, as well as in inguinal herniorrhaphy.ConsentWritten informed consent was obtained from the patientfor publication of this case report and any accompany-ing ... after repair of bilateral inguinal hernias. Itis important to pay attention to the seminal tracts dur-ing herniorrhaphy of an omphalocele, as well as in ingu-inal herniorrhaphy.The v asa de ferentia ... causes of iatrogenic injury are vasectomy and bilateral inguinalherniorraphy [3]. There have been several reports of other causes of iatrogenic injury, including hydrocelect-omy [4], appendectomy...
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Báo cáo y học: " Incisional hernia as an unusual cause of hepatic encephalopathy in a 62-year-old man with cirrhosis: a case repor" ppsx
... cirrhosis,and it is associated with shortened survival. In addition,the poorer prognosis of patients with cirrhosis and HE hasbeen reported in male patients, patients with increasedserum bilirubin and ... after evaluating thepossible benefits and risks of the surgery.AbbreviationsALT, alanine aminotransferase; AST, aspartate aminotrans-ferase; HE, hepatic encephalopathy; INR, internationalnormalized ... glucose 115 mg/dl,creatinine 0.7 mg/dl, a lkaline phosphatase 220 U/L, aspartateaminotransferase (AST) 18 U /L, alanine aminotransferase(ALT) 30 U /l, g-glutamyl transpeptidase 20 U/l, total bilirubi...
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Báo cáo y học: " Multiple cysticerci as an unusual cause of mesenteric lymph node enlargement: a case report" ppsx
... Otherinvestigations showed inflammatory granulomas in thebrain and the presence of anticysticercal antibodies in theserum and cerebrospinal fluid [4]. An unusual presentation of cysticercus infestation ... cysts, some containing shiny grey-white parasites.Photomicrograph showing parts of two cysticerci with inter-vening lymphoid tissueFigure 2Photomicrograph showing parts of two cysticerci with ... into adult worms. They may remain herewithout causing any symptoms, or may be responsible forvague abdominal discomfort or intestinal disorders andanemia. The gravid terminal proglottids of...
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Báo cáo y học: " Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review" pps
... most of its course.The classic presentation of pain, haematuria, and flankmass occurs in a minority of patients and is often indica-tive of advanced disease. A tumour in the kidney canprogress ... Approximately30% of patients with renal carcinoma present with meta-static disease, 25% with locally advanced renal carcinoma,and 45% with localized disease [1]. About 75% of patients with metastatic ... systemic circulation. Headand neck metastasis is commonly associated with lungmetastases. If there are no signs of pulmonary disease, as in our case initially, it is possible that spread has...
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Báo cáo y học: "Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis" potx
... function in an autocrine or paracrinefashion, and increased expression of IL-18 in the syn-ovium may play a critical role for development of synovial inflammation, synovial hyperplasia, and articular ... inflam-mation during an acute response that may offer insightinto early proinflammatory cytokine release in the initialphases of the inflammatory response. This is often lost byusing models such as CIA ... 29:369-378.9. Yamamura M, Kawashima M, Taniai M, Yamauchi H, Tanimoto T, Kurimoto M, Morita Y, Ohmoto Y, Makino H: Interferon-gamma-inducing activity of interleukin-18 in the joint with rheumatoid arthritis. ...
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Báo cáo y học: "Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy" pps
... expression.Since plasma membrane recruitment of Akt kinase typi-cally results in increased phosphorylation and activation of Akt, we hypothesized that HIV-1 infection might leadto an increase in Akt kinase ... by FLAG-tagimmunoprecipitation and examined by Western blotanalysis using antibodies directed against the C-terminalV5-tag of PTEN. As seen in Figure 4B, the binding of PTENto p53 was drastically ... SD from three independent experiments. (B) Assay for Akt kinase activity. Macrophage and CHME5 cells were trans-duced with HIV vector and lysed. Using these lysates, an Akt kinase activity assay...
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Báo cáo y học: " Landmark survival as an end-point for trials in critically ill patients – comparison of alternative durations of follow-up: an exploratory analysis" doc
... is often used in many clinicaltrials as the primary end-point, not only in ICU medicine butalso in cardiology and oncology.This study has several strengths. It formally addresses the important ... mortality assessment difficult to interpret. Measurement of mortality at 28-days or censoring at hospital discharge havelogistic advantages but as many as one-third of critically ill patients may ... sufficient.This information is important in providing an evidence-basedapproach in designing and interpreting randomized controlledtrials involving these conditions.Competing interestsThe authors...
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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf
... Pharmingen) and anti-VE-Cadherin-PE (eBio-science), or Annexin-FITC and 7-Amino Actinomycin D(7-AAD BD Pharmingen) and analyzed by FACS. Onceagain to assess cellular viability an aliquot of cells ... DevelopmentAnti-CD52 antibodies (MBL Cambridge, MA) were bioti-nylated per protocol (Pierce). Biotinylation was con-firmed by FACS analysis of murine splenocytes usingbiotinylated anti-CD52 antibody ... significant history of clinical usewill allow immediate proof -of- principle cancer therapyclinical trials in humans.AbbreviationsANOVA: Analysis of Variance between Groups; CLL:Chronic Lymphocytic,...
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