Báo cáo y học: "Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis" pps
Báo cáo y học: "Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis" pps
... project running and data analysis, and drafted the manu-script. TM, SF, YI, YK, and HM assisted in the study design and coordination, and oversaw the data analysis and drafting of the manuscript. ... the original work is properly cited.Research articleCharacterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosisNobuyo Higashi-Kuwata1, ... evaluated the expression of CD163 and CD204 and various activated macrophage markers, in the inflammatory cells of the skin and in the peripheral blood mononuclear cells (PBMCs) derived from patients...
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Báo cáo y học: "Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation" ppsx
... implantation rather thanwithin 18 months of implantation. Moreover, we noted a corre-lation between the symptomatology of patients and the nature of the reparative tissue. Asymptomatic patients developed ... were confirmed by analyses of biopsies with polar-ized microscopy, which demonstrated the presence of typicalhyaline collagen fibrils parallel to the surface of the biopsy with a normal cartilage ... of the newly formed tissue overtime. Cartilage maturation occurred from the inner regions of the graft, in contact with subchondral bone, towards the periphery of the implant.Conclusions The...
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Báo cáo y học: " End-of-life issues in the acute and critically ill patient" pdf
... refractory symptoms in dying patients. J Pain Symptom Manage 2008 in press.21. Castellano G: The criminalization of treating end -of- life patients with risky pain medication and the role of the extreme ... In contrast to the Japanese, Indian patients tend to be more open and develop a deeper interaction with their physicians. Theyvalue the advice of their doctors and correspondingly fol-low their ... objectives of their own medical care.Some patients may choose to forego life-sustaining medi-cal therapies and interventions near the end -of- life. The primary role of the emergency physician near the...
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Báo cáo y học: "Characterization of viroplasm formation during the early stages of rotavirus infection" ppsx
... been involved in data analysis and revisingfinal manuscript, SL participated in designing of the study and in criticalreading of manuscript, PI conceived of the study, has been involved in Cy5-TLP’s: ... assembly [8]. In thiswork we tested this hypothesis by visualization of incom-ing viral particles and by analyzing their colocalization with newly formed viroplasms. Only 2 out of 117 CY5-conjugated ... 8hNSP2multiplicity of infectionFigure 4 The amount of NSP2 protein increases with time of infection. MA104 cells were infected with RRV at the indicated MOI, and atdifferent times post-infection at 37°C, the...
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Báo cáo y học: " Characterization of lymphocyte populations in nonspecific " doc
... characterized bya largely lymphocytic infiltrate, with a high CD4/CD8ratio, rich in cytokines, predominantly exhibiting a Th1type response. These findings may in part explain whyNSIP, in comparison ... were counterstained with 1% hematoxylin. The percentage of positively stained cells in each sample was determined by counting stained and non-stained mononuclear cells in 5 randomly selectedcontiguous ... MayoFoundation.Acknowledgements The authors thank Dr. Jay Ryu and the members of the Mayo Interstitial Lung Disease focus group for identification and clinical management of these patients with NSIP. The authors further...
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Báo cáo y học: " Characterization of antibodies elicited by XMRV infection and development of immunoassays useful for epidemiologic studies" potx
... competitively inhibit the anti-MuLV pAbbinding to the corresponding native proteins on WB. Asshown by Figure 1B (strips 2-6), band intensity of the native proteins decreased by 90-100% in the presence ... presence of the corresponding recombinant proteins confirming the banding positions for the na tive viral pr oteins: p15, p12,p30,p10andp15E.Thebandingpositionofgp70wasconfirmed by competitive inhibitio ... were infected with XMRV to determine the dynamics of the antibody responseselicited by infection with XMRV. All macaques developed antibodies to XMRV during the second week of infection, and the...
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Báo cáo y học: "Characterization of Kupffer cells in livers of developing mice" ppt
... lining of the liver sinusoids, acting tophagocytose foreign particu late matter from the circulat-ing blood. In recent years, the use of mice, and particularlygenetically engineered mice, in ... immunocytochemistry methods. KJL participated in the design of the study and analysis of the results. RTR participated in the design of the study, performed some of the injections and perfusions, ... were injected intravascularly, they werefound virtually continuously in the lini ng of the sinusoi-dal capillaries of the liver (Figure 2G,H,I). Some of thesesmaller microspheres were found within...
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Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... set of themes as reached via consensus.This process involved examining themes for commonal-ity, classifying them for uniformity, and then reachingagreement on the final list of six key themes. ... the providers, and that the nature of the referral (e.g., amount and type of information accompanying the referral) maydepend on the nature of the condition, whether the refer-ral is for reasons of diagnosis ... and these can beenhanced by creating multidisciplinary panels to explic-itly improve cross-disciplinary coordination of care.Competing interests The author(s) declare they have no competing interests.Authors'...
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Báo cáo Y học: Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase A site-directed mutagenesis study docx
... to Y2 24 of the mammalian enzyme (the residueinteracting with the a-amino group of the substrate and with a buried water molecule). Y2 24 in pkDAAO and Y2 38 in RgDAAO share the characteristics of ... measuredby the dye equilibration method of Minnaert [17], in orderto assess changes in the thermodynamic properties of the flavin centre caused by the mutation and to explain the different thermodynamic ... result of a better interaction of R285 with the N(1)-C(2)¼O locus of the reduced flavin following the substitution of Y2 38 with a serine (the distance between the side chains of R285 and Y2 38 is...
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Báo cáo y học: "Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years" ppt
... (TNF), a proinflammatory cytokine, is present in biopsies of sacroiliac joints of patients with active disease, suggestingTNF involvement in the inflammatory process of AS [2]. The TNF antagonists ... for the OASIS study and was the adjudicator for the radiographic reads. DvdH was the prin-cipal investigator of the OASIS study and is the principalinvestigator who assisted in designing the ... antagonist therapy [23].Initiation of anti-TNF therapy in patients with very early AS orpreradiographic spondyloarthritis may prevent radiographicprogression in the spine, but there are no data as of...
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