Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt
Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt
... of these cells.Density of neutrophils in synovial tissues of patients with OA and RA The presence of HNP1-3 prompted us to study the den-sity of elastase-positive neutrophils in synovial tissues ... defensins from synovial tissue/ cells and density of synovial neutrophils. (a) Levels of human neutrophil pep-tides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid ... 3d). The relatively low density of neutrophils is due to the factthat neutrophils were present mainly in the lining and adjacent sublining area but not in deeper layers of the synovial tissue, ...
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Báo cáo y học: " α Tumor necrosis factor-α and muscle wasting: a cellular perspective" docx
... degradation. The marked protein is then degraded by the 26S-proteasome complex, by an ATP-dependentprocess. In catabolic states, the activity of the ubiquitin/proteasome pathway is increased by upregulation ... that involves phospho-rylation and proteasomal degradation of the NF-κB-inhibitory protein, Iκ-Bα [13]. NF-κB activity in the cellnucleus peaks within 30 minutes of TNF-α exposure and then ... components of the inflammatoryresponse and are sensitive to other ligand/receptor inter-actions (e.g. interleukin-1 and interleukin-6). Perhaps ROS and NF-κB represent upstream elements of a commonpathway...
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Báo cáo y học: "Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte" pptx
... promotes further expression of cytokines and chemokines by synovial cells and chondro-cytes, thereby sustaining a renewal of local inflammatorymediators (reviewed in [9,10]). The presence of TNF-α ... morphology. The MAPK/ERK pathway is thereby at least partially involved in regulating the aggrecan and type II collagen genes and in remodeling of the cytoskeleton in response to factorspresent during ... [12]. In rheumatic joints, elevated levels of EGF in the synovial fluid contribute to hyperplasia of the synovial lining,where synovial cells display increased expression of the EGF receptor ErbB-2...
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Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt
... was involved in the design of the study, performed all the experiments and wrote the manuscript. PB was involved in performing cell cultures, flow cytometry and gel shift assays, and reviewed the ... design of the study and reviewed the article critically. AC was involved in the conception and design of this study, in the interpretation of data and reviewed this arti-cle critically. BP and ... E-selectin and intercellular adhesionmolecule, necessary for the flow of leucocytes into the sub-endothelial tissue [6]. It also promotes production of otherproinflammatory cytokines and chemokines,...
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Báo cáo y học: "Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis" pptx
... expression levels of TIARP mRNA and proteins were detected in splenocytes on day 7 (the onset of arthritis). In joints, the expression of TIARP mRNA and protein was correlated with joint swelling (days ... Thesefindings suggest that the systemic upregulation of TNFα and TIARP is involved in the early phase of the disease and thatTIARP expression in arthritic joints seems to correlate withjoint ... increased in the joints (accompanied by joint swelling), especially in hyperplastic synovium. Overex-pression of the human TIARP counterpart, such as six-trans-membrane epithelial antigen of...
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Báo cáo y học: "Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro" pptx
... manuscript critically for importantintellectual content. BK was involved in the conception and design of the study, analysis and interpretation of the data, and did most of the drafting of the manuscript. ... vanden: Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced ... from the stimu-lated samples and the control.ZymographyProtein levels of MMPs were assayed in conditioned media by gelatin and casein zymography. Equal volumes of mediumsamples and loading...
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Báo cáo y học: "α Tumor necrosis factor-α blockade in ankylosing spondylitis: a potent but expensive anti-inflammatory treatment or true disease modification" pps
... http://arthritis-research.com/content/7/3/R439123decrease in the hypervascularity typical of SpA and areduction of the synovial lining hyperplasia, indicating thatinfliximab also modulates the structural synovial charac-teristics of the disease. ... acceptable safetyprofile in the chronic treatment of rheumatoid arthritis. Notonly did the therapy turn out to alleviate signs and symptoms,but it also improved greatly the quality of life of the patients, and ... matrixmetalloproteinases and their inhibitors in peripheral synovitis and down regulation by tumor necrosis factor- ααblockade in spondyloarthropathy. Arthritis Rheum 2004, 50:2942-2953.Available online...
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Báo cáo y học: "Tumor necrosis factor-a enhances hyperbaric oxygen-induced visfatin expression via JNK pathway in human coronary arterial endothelial cells" ppt
... abolished the DNA-proteinbinding activity induced by HBO. Exogenous addition of TNF-a significantly increased the DNA-protein bindingactivity. To study whether the visfatin expressioninduced by HBO ... HBO-induced visfatinproteinexpressionin human CAECs. Thirdly, JNK kinase and AP-1 transcrip-tion factor are involved in the signaling pathways of visfa-tin induction by HBO. Fourthly, HBO increases ... uptake by HBO. This finding indicates that visfatinmediates the glucose uptake by HBO in human CAECs.GlucoseuptakeincreasebyHBOmayimprovetheenergy metabolism in CAECs which may provide myo-cardial...
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Báo cáo y học: "Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-B-dependent pathwa" pptx
... pyrimidine s for DNA and RNA synthesis and accu-mulation of AICAR. AICAR, by inhibiting enzymaticdeamination of adenosine and adenosine monopho-sphate, is proposed to increase availability of ... signaling.Conclusions: These find ings provide another mechanism by which TNF-a sustains macrophage numbers in inflamed tissue and identify a further point of clinical complementarity between MTX and anti-TNF-a ... We, therefore,investigated this proposal and the macrophage signaling pa thways underlying it.Methods: Caspase-3 activity, annexin-V binding/7-aminoactinomycin D (7-AAD) exclusion and cell-cycle...
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Báo cáo y học: "Tumor Necrosis Factor-α +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease" doc
... characterized by a chronic inflammatory process, in which the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α is considered to play a role. In the present study the putative involvement of TNF-α ... would further enhance the strength of these kinds of stud-ies. The gene polymorphism of TNF-α +489G/A was de-scribed for the first time in 1996 and is located in the first intron of the gene ... [27] and in circulation [28] of COPD patients, indicating that this cytokine is involved in both the local and systemic inflammation present in COPD. Analysis of possible TNF-α gene polymorphisms...
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Từ khóa: chuyên đề điện xoay chiều theo dạngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam