Báo cáo y học: "Functional significance of nerve growth factor and its receptor (TrkA) in inflammatory arthritis" pps

... article by Barthel and colleagues [1] in this is sue of Arthritis Research &  erapy with great interest.  ey reported that neurotrophin receptors/ligands and specifi cally nerve growth factor ... by proliferation of FLSs, in ammatory in ltrates, and a marked angio- genesis. NGF and its receptor system are known to © 2010 BioMed Central Ltd Functional signi...

Ngày tải lên: 12/08/2014, 14:21

... 1,3-b-glucans [5], its intra- cellular signalling has been demonstrated to be mediated by Raf-1 and Syk-CARD9 dependent pathways to induce production of pro -inflammatory cytokines and reactive oxygen species ... at baseline, year 1, 2, and 3, and every third year thereafter. Radiographs of hands and feet were read in chronol ogic order by one of four raters, according to...

Ngày tải lên: 12/08/2014, 11:23

... plexus injury has been increasing world wide mainly because of rapidly growing number of motor cycle accidents. Most of these injuries are high velocity injuries resulting in root avul- sions. ... and SRS were the main operating surgeons and designed the study, PB and SRJ performed data collection and analysis of the results, HR and PB were involved in sequence alignment...

Ngày tải lên: 10/08/2014, 10:20

... in the presence of equimolar amount of trypsin, only the inactivation rate of Phe114!Ile D-chymotrypsin was accelerated, while that of D-chymotrypsin and Tyr146!His/Asn147!Ser D-chymo- trypsin ... chymotrypsin. D-Chymotrypsinogen is a chimera constructed to contain a trypsinogen propeptide instead of the Cys1–Cys122-linked wild-type chymotryp- sinogen peptide. D-Chymotrypsinogen...

Ngày tải lên: 22/02/2014, 07:20

... [12,15,27]. Overgrowth of blood vessels may lead to the development and progression of diseases such as tumor growth and diabetic retinopathy. Many lines of evidence support the original hypothesis ... effects of growth factors in the study of angiogenesis. CAM is the method that involves observation of the growth of vessels in the chick embryo. Because CAM is perf...

Ngày tải lên: 07/08/2014, 15:20

... Ha 4 ,Man-HeeRhee 5 ,Kang-YiLee 6 and Moo-Kang Kim * College of Veterinary Medicine, Chungnam National University 1 Chungnam Veterinary Service Laboratory, 2 College of Medicine, Konyang University 3 Korean Research Institute ... of bioscience and biotechnology (KRIBB), 4 College of Medicine, Kangwon National University 5 Department of Cell Biology & Physiology College of...

Ngày tải lên: 07/08/2014, 15:20

... history of gastropathy are well known inde- pendent risk factors for gastrointestinal bleeding, and it is therefore not surprising that they influenced prescribing practices. The effect of sex may ... with celecoxib (3.4%) and rofecoxib (18.2%). Conversely, the majority of COX-2 inhibitors were prescribed at standard anti -inflammatory dosages (65.3% of celecoxib and 73.0% of...

Ngày tải lên: 09/08/2014, 06:22

... mice and underlines the important role of fibrin in inflammation. These may be mediated by fibrin- induced macrophage secretion of proinflammatory cytokines such as IL-1β and TNFα [33-35] and of ... Fibrin immunostaining in the footpad was graded independently by two observers unaware of animal treatment on a scale of zero (no fibrin at all) to six (maximum of fibrin sta...

Ngày tải lên: 09/08/2014, 10:23

... streptomycin, pH 7.4 (maintain medium). Cells were passaged every 5 to 7 days to maintain exponential growth. DEN-1 strain GZ02-218 was passaged by infecting monolayers of C6/ 36 cells and viruses ... replication and in creased C6/36 cell survival rate. siRNA may offer a potential new st rat- egy for prevention and treatment of DEN infection . The stability and inhibitory effic...

Ngày tải lên: 12/08/2014, 01:22

... Caucasian Type of skin involvement No scl dcSSc No scl No scl dcSSc dcSSc Pitting scars Y Y Y Y Y ILD Y Y Y Y Y Raynaud phenomenon Y Y Y Y Y Y Pulmonary hypertension Y Esophageal dysmotility Y Flexion ... s tudy meets and is in compliance with all ethical standards in medicine, and informed consent was obtained from all patients accord- ing to the Declaration...

Ngày tải lên: 12/08/2014, 15:23