Báo cáo y học: "Potential mechanisms underlying the acute lung dysfunction and bacterial extrapulmonary dissemination during Burkholderia cenocepacia respiratory infection" pptx

... H Open Access Potential mechanisms underlying the acute lung dysfunction and bacterial extrapulmonary dissemination during Burkholderia cenocepacia respiratory infection Luiz G Cunha Jr 1 , Maria-Cristina ... analysed in both in vitro and in vivo assays. Methods: B. cenocepacia- infected BEAS-2B epithelial respiratory cells were used to investigate the bact...

Ngày tải lên: 12/08/2014, 14:20

... [9], which could alter their ability for learning and memory. Another molecule that has been shown to play a key-role in the cellular processes underlying learning and memory is Brain Derived Neurotrophic ... laboratory have shown that handled male rats show increased 5-HT1A receptor sensitivity as assessed by the hypothermic response to 8-OH-DPAT compared to the non-handled [26]....

Ngày tải lên: 08/08/2014, 21:20

... through the gut or its mucosal associated lymphoid tissue, and exposed to enteric antigens, are preferentially able to bind to the syn- ovial endothelium and are therefore selectively recruited to the ... the synovial fluid T cell repertoire and the acute phase response suggests that proinflammatory cytokines may influence recruitment of memory T cells to an inflammatory sit...

Ngày tải lên: 09/08/2014, 01:23

... activity in SKOV3 cells. In our EMSA analyses, aside from the shifted band that contained USF1 and USF2, we observed other shifted bands (X and Y) . As bands X and Y were only partially inhibited by ... of the SHP-1 phosphatase domain, and the intensity of the autoradiographed bands was measured by densitometry. We analysed six human hematopoietic cell lines (K562, Raji, HL...

Ngày tải lên: 08/03/2014, 23:20

... lymphocytes then can induce vigorous B lymphocyte proliferation and direct the differentiation of the clonally expanded progeny of naïve B lymphocytes into either plasma cells or memory B lymphocytes. ... radiation) in the respiratory tract or through the skin leads to the cleavage of histidyl-tRNA synthetase by granzyme B through antiviral CD8 + T lymphocytes in the lungs. (2...

Ngày tải lên: 09/08/2014, 10:20

... probably reflects low affinity binding to heparan-like glycosaminoglycans [37]. As the myc-his tag of the protein was present at the C-terminus of the receptor which is located on the inside of the ... °Cfor30minwith 10 n M of MIP-1a and then the CCR5 present on the plasma membrane was quantified by FACS analysis using the 2D7 antibody (Fig. 2B). It was found that the 60–70...

Ngày tải lên: 08/03/2014, 09:20

... during the first week of their hospi- talisation by three independent psychiatrists-raters. The first rater assessed the patients using the RPAS and the AIMS, the second using the PANSS and the ... significantly related to general psychopathol- ogy symptoms, estimated by both the PANSS and the BPRS. We did not find any studies exploring the the relationship betwe...

Ngày tải lên: 08/08/2014, 21:20

... larynx, and trachea (two mice from the acute phase and two from the chronic phase). As was seen in the QD and B10.Q mice, more macrophages were observed in the acute than in the chronic stage. All the ... matrilin-1 and there was a tendency towards correlation between the titer of anti-matrilin-1 antibodies and clinical symptoms, in both the IL-10-deficient and...

Ngày tải lên: 09/08/2014, 01:24

... contributions GSM, HBM and KBL conceived the idea and obtained funding for the study. GSM, HBM and KBL designed the study protocol. GSM recruited participants, conducted the laboratory testing and processed ... was reported by a study comprising older adults with long- standing rheumatoid arthritis [8]. Therefore, other than the early descriptive work of Gray and Basmajian...

Ngày tải lên: 10/08/2014, 21:24

... study, and partici- pated in the design of the study and performed immu- noassays, FACS analysis, statistical analysis, and wrote the first draft and final version of the manuscript. KK, AK IR and ... stim- ulating the synthesis of the cellular GSH levels and therefore protecting the cells against oxidants (indirect effect) by modulating the redox signaling pathway...

Ngày tải lên: 11/08/2014, 08:22