... findings of NO involvement in pathophysiol- ogy of hypobaric hypoxia in brain (42-43). In this study the increased activity of NOS in anoxia may represent predominantly the nNOS form. In inflam- matory ... activity of nitric oxide synthase. The increased activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased and effective recycling of cit...
Ngày tải lên: 26/10/2012, 09:07
... dyssynchrony during dobutamine stress in patients with wide QRS duration (20). In contrast, Kurita et al. reported on an increased mechanical dyssynchrony during pacing–induced tachycardia in patients ... biventricular pacing typically improves the time course of cardiac contraction at rest and during exer- cise by reducing LV dyssynchrony and thereby liber- ating a further se...
Ngày tải lên: 05/11/2012, 11:32
Tài liệu Báo cáo Y học: Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells ppt
... recombinant proteins leading to a compromised mitochondrial integrity rather then to an intrinsic property of the proteins. T his could e xplain the lack of r egulation by free fatty acids and purine ... folding and thus does not represent a physiologically relevant function of the protein. These findings imply that, r esults and phenotypes obtained after overexpression of UCP3, and po...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx
... significantly inhibited IP-10 induction. These results suggest that IP-10 expression within inflamed joints appears to be regulated not only by inflammatory cytokines but also by the physical interaction ... chemokines and proinflammatory cytokines is probably important in the orchestration of the inflammatory responses observed in patients with RA [1–4]. Chemokines belong to a gene...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthri" pdf
... corresponding to the microscopic findings in hematoxylin and eosin staining. In addition, leukocyte infiltration into the synovial fluid of the inflamed knee joints following rTRAIL treatment was reduced ... degree of TUNEL staining in synovial tissue sections. Investigators blindly reviewed primarily two areas: synovial lining and subsynovial regions. The extent of staining in...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "A model of anti-angiogenesis: differential transcriptosome profiling of microvascular endothelial cells from diffuse systemic sclerosis patients" potx
... out. Figure 3 Expression and role of pent(r)axin 3 (PTX3) in endothelial cell invasion and capillary morphogenesisExpression and role of pent(r)axin 3 (PTX3) in endothelial cell invasion and capillary morphogenesis. ... cell invasion and capillary morphogenesisExpression and role of desmoglein (DSG)2 in endothelial cell invasion and capillary morphogenesis. (a) Western b...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Functional outcome of nerve transfer for restoration of shoulder and elbow function in upper brachial plexus injury" potx
... transfer by reinnervating most functionally impor- tant nerves using intact neighboring nerves has become widely accepted since it was reported by Seddon in 1963 [23]. Since then variety of donor ... contributions HR and SRS were the main operating surgeons and designed the study, PB and SRJ performed data collection and analysis of the results, HR and PB were involved in sequen...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " Efficient delivery of small interfering RNA for inhibition of IL-12p40 expression in viv" pdf
... a pro-inflammatory cytokine in cell medi- ated immunity against microbial insult. In particular IL- 12p70 acts upon T and NK cells to increases cytokine pro- duction, proliferation, and cytotoxicity, ... Gazzinelli RT, Hieny S, Wynn TA, Wolf S, Sher A: Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces r...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: " Atypical right diaphragmatic hernia (hernia of Morgagni), spigelian hernia and epigastric hernia in a patient with Williams syndrome: a case report" ppsx
... Ahmed 2 and Syed Y Iftikhar 2 Address: 1 Division of GI Surgery, Clinical Sciences Wing, The Medical School, Derby City General Hospital, Uttoxeter Road, Derby, DE22 3DT, UK and 2 Derby City General ... this defect enlarges in size, resulting in respiratory or abdomi- nal symptoms. The hernial sac usually contains omen- tum, transverse colon and rarely stomach [5]. Increasing...
Ngày tải lên: 11/08/2014, 19:21
Báo cáo y học: "Molecular characterization of hepatitis A virus isolates from environmental and clinical samples in Greece" pptx
... (environmental and clin- ical) by employing previously validated primer sets [9]. Sequencing and analysis of viral genomes All positive samples (environmental and clinical) were confirm ed by se quencing ... setting up and coordinating the study, and drafted the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have n...
Ngày tải lên: 12/08/2014, 01:21