Báo cáo y học: " The bioavailability and airway clearance of the steroid component of budesonide/formoterol and " docx
Báo cáo y học: " Gut flora enhance bacterial clearance in lung through toll-like receptors 4" docx
... inflammatory injury to the lung. The influence of the gut-lung axis on lunginjury and immunity has been known for years, yet the underlying mechanism is not completely understood [3].It has previously ... anesthetized and the thorax was opened withmedian sternotomy. The bilateral lungs and heart wereharvested together and the pulmonary vasculature wascleared of bl ood by gentle injection of 10 ml ... 72°C, thenfinally 10 min at 72°C after the last cycle. We recorded the electrophoresis by CCD camera and compared the band intensity by Kodak Digital Science TM ID ImageAnalysis Software (Eastman...
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Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot
... orange. Otherbinding residues (W9AMY2, H92AMY2, T94AMY2, A95AMY2, Y1 30AMY2, A145AMY2, F180AMY2, K182AMY2, W206AMY2,S208AMY2, Y2 11AMY2, H288AMY2, Q294AMY2, M296AMY2 and Q35TAA, ... pat-terns of wild-type and the majority of the mutants, however, reflected the importance of the high-affinity subsite )6[44],where Tyr104AMY1(Tyr105AMY1) was stacking onto gluc-osyl at the nonreducing ... acti-vity in the zymogram and exchange by Asp (Fig. 2) and Glu(not shown) did not significantly decrease the pI.Enzyme kinetic properties of AMY1 mutants The activity of Met53 mutants and wild-type...
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Báo cáo y học: "Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy" pptx
... level of suspicion and the families of patients atrisk are made aware of the possibility of this side e ffect. The symptoms of adrenal crisis include: hypotension and unexplained, acute hypoglycemia ... factorscontributing to the potential for systemic side effects. Ashort-half life and high clearance rate reduce the expo-sure of the ICS to the systemic circulation, therebyimproving the safety profile. The ... advantageous for the oral bioavailability of an ICS to be relatively low. The oral bioavailability of the currently available ICSs varieswidely, from approximately <1% for ciclesonide and flu-ticasone...
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Báo cáo y học: "Psoriatic arthritis synovial histopathology: commentary on the article by Kruithof and colleagues" pps
... classify PsA may have little clinical utility.PsA belongs to the SpA family, and the focus should be ontrying to identify features, perhaps common to the targettissues (skin, synovium and enthesis), ... associated with PsA and that togethersuggest a unique clinical entity. At the very least, the jointdisease in PsA is modified by the presence of Ps to producea form of SpA with easily distinguished ... of unselected patients. While the results of this study are eagerly awaited, it is possible thatdividing patients up by the number of joints involved has littlerelevance other than identifying...
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Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... at1 year and 2 years of 96% and 89% compared withViewpointCold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertensionFrances C HallUniversity of ... astate of progressive chronic organ ischaemia. Dysfunction of cellular components of the arterial wall and dysfunction of inflammatory and haemostatic systems are interrelated(Fig. 1) [3,4]. Endothelial ... cell dysfunction is characterised bydecreased production of the vasodilators nitric oxide and prostacyclin, and by enhanced release of endothelin-1.Endothelial cell dysfunction influences the...
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Báo cáo y học: "No evidence for an association between the -871 T/C promoter polymorphism in the B-cell-activating factor gene and primary Sjögren''''s syndrome" pptx
... allelefrequency of 46%. Five other SNPs, previously reported inJapanese patients with rheumatoid arthritis (RA) and systemiclupus erythematosus (SLE) [7], were not detected in the present study of Caucasian ... wasanalyzed using analysis of variance. Statistical analysis wasperformed using Analyse-it for Microsoft Excel (Leeds, Eng-land, UK).Results The allelic and genotypic distribution of -871 ... characteristics of the patients aresummarized in Table 1. The patients were receiving no immu-nosuppressive medications other than corticosteroids (dailydose of ≤10 mg of prednisone; n = 14) or hydroxychloroquine(n...
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Báo cáo y học: "Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix" ppsx
... that chondrocytes and annulus cells are twocompletely different mature cell types as illustrated by the matrix they produce and by their biochemistry [12]. Previouswork [35] on type II A pro-collagen ... proteoglycan production may be causedby effects such as secreted growth factors released by eithercell type enhancing the overall ECM production, or by modifi-cation of the microenvironment of the ... proteoglycan and collagen type Irich ECM after treatment with TGFβ in 3D culture as confirmedby a 48% increase in proteoglycan content assayed by 1,9-dimethylmethylene blue (DMB), and by immunohistochemicalidentification...
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Báo cáo y học: " Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis" pot
... RP105 expand in the peripheralblood of patients with systemic lupus erythematosus [32] and that these cells can produce anti-double-stranded DNA anti-body [33]. On the other hand, Divanovic and ... nevertheless support a regulatory role of RP105in the development of arthritis induced by TLR ligands. On the other hand, these in vivo results cannot be explained by the invitro data of splenic ... inflammatory cytokines by APCs activatedby immunization with CII and CFA.Next, we tried to elucidate whether the regulatory role of RP105 in the development of arthritis is exerted only when the disease...
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Báo cáo y học: " NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitid" pot
... metabolism(complete sets of enzymes for glycolysis, the tricarboxylic acidcycle, gluconeogenesis and both pentose-phosphate and Entner-Doudoroff pathways) and may be capable of de novosynthesis of all 20 ... completion of the collection of mutants (eitherthrough gene-by-gene or systematic targeted mutagenesis of the missed genes), further improvement of the accuracy of the annotation by taking into ... insertionapproximately in the middle of the target gene - were readilyidentified by colony-PCR by using a mix of ISL and ISR, and the forward primer used to amplify the target gene. Plasmidswere then extracted,...
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Báo cáo y học: "Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle" doc
... tocharacterize the participation, if any, of these proteins in the process of entry into the cell cycle of G0, growth arrested cells(G0/G1 transition) and the subsequent steps of progressionthrough early ... in this study involved inmost instances the comparison of the profiles of G0-arrestedWT cells with those of the other samples and conditions stud-ied here by means of microarray hybridization. ... differentpeaks of Ras activity during the initial stages of the cell cycle and confirm the notion of functional specificity for the H-Ras and N-Ras isoform proteins.Materials and methodsCell...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngTranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ