Báo cáo y học: " Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells" pdf

... initiation of infection and dissemination of influenza H5N1 infection in humans. These are polarized cells and the polarity of influenza virus entry and egress as well as the secretion of cytokines and ... the infection of polarized, primary, human type I-like alveolar epithelial cells and lung microvascular endothelial cells by influ- en...

Ngày tải lên: 12/08/2014, 14:20

... replication and virulence. Materials and methods Cells and viruses Madin-Darbycaninekidney(MDCK )cells ,human embryonic kidney cells (293T), mouse kidney epithelial cells (M1), and human lung epithelial cells ... University of Ottawa, Department Of Biochemistry, Microbiology and Immunology. SKD, SW and NEF are PhD students at the University of Ottawa, Depar...

Ngày tải lên: 11/08/2014, 21:21

... splicing of viral mRNAs and that it is localised in the nucleus i n an early stage of infection, while in later stages of infection it predominantly resides in the cytoplasm. This cytoplasmic ... work and our recently established sys- tem for the rescue of recombinant influenza C viruses [20], NS1-mutated attenuated recombinant influenza C viruses may be created to investi...

Ngày tải lên: 11/08/2014, 21:22

... N, Arora U, Singh K: Prevalence of human immunodeficiency virus (HIV), hepatitis B virus, and hepatitis C virus in three groups of populations at high risk of HIV infection in Amritsar (Punjab), ... Fischer D: Estimated Prevalence of Viral Hepatitis in the General Population of the Municipality of Sao Paulo, Measured by a Serologic Survey of a Stratified, Randomized...

Ngày tải lên: 12/08/2014, 04:20

... obtained by limiting dilutions and colonies were vis- ually scored for low basal level of ECFP expression in the cytoplasm and to be highly inducible by GST-Tat by fluo- rescence microscopy. The ... aspect of HIV-1 pathogenesis is the control of provirus transcription. In particular the ability of the virus to maintain a reservoir of transcriptionally silent provi- ruses in re...

Ngày tải lên: 13/08/2014, 05:21

... William K. K. Wu, Vivian Y. Shin, Wallace H. L. So and Chi Hin Cho Centre of Infection and Immunology and Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, ... polyclonal B cells [20], induce interferon [21] and also activate helper T cells [22]. Lymphocyte proliferation assays, e.g. mitogen-mediated lymphocyte proliferation t...

Ngày tải lên: 02/11/2012, 10:19

... characterizing genetic pathways involved in synoviocyte pathophysiology. Prior work has suggested that FLS are relatively refractory to infection by Moloney murine leukemia virus based vectors. To ... arthritis. Much of our understanding of this biology has been derived from the study of primary fibrob- last like synovial cells cultured from arthritic joints after arthroscopic bio...

Ngày tải lên: 09/08/2014, 03:24

... components of the host immune and inflammatory response. Statins modify endothelial dysfunction – effects on inflammatory initiation and perpetuation via endothelial cells Effects of statins on endothelial ... (RA). Pharmacology of the HMG-CoA reductase inhibitors The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG- CoA) reductase catalyses the conversion of HMG-CoA to m...

Ngày tải lên: 09/08/2014, 06:22

... cell aggregates, and this was unaffected by low oxygen. In non- FGF2-expanded cells, biglycan and fibromodulin expression was similar in monolayer and cell aggregates, but biglycan was increased by low oxygen ... resem- bles that of the chondrocytes of articular cartilage [1], they produce predominantly type I collagen with smaller amounts of types II, III, V and VI collagens,...

Ngày tải lên: 09/08/2014, 07:20

... primary PD, Type 1 is primary intraepithelial PD, Type 2 is primary intraepithelial PD with invasion and Type 3 is primary intraepithelial PD as a manifestation of underlying adenocarcinoma of skin Photograph ... of the Paget's cells has been proposed by Wilkinson and Brown [3]. They classified vulval Paget's disease (PD) into two broad groups – primary (of cutaneous or...

Ngày tải lên: 11/08/2014, 19:21