Báo cáo y học: " Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation" ppt

... MPAP, mean pulmonary arterial pressure; PAC, pulmonary arterial catheterization; PAH, pulmonary arterial hypertension; PVR, pulmonary vascu- lar resistance; RVSP, right ventricular systolic pressure ... assessments by right heart catheterization: SPAP, systolic pulmonary arterial pressure; MPAP, mean pulmonary arterial pressure; PAOP, pulmonary arterial occlusive pre...

Ngày tải lên: 11/08/2014, 17:21

... Synthesis. I The Synthesis of a Tetrapeptide. J Americ Chem Soc. 1963; 85: 2149-54. 27. Paquet A. Introduction of 9-fluorenylmethoxycarbonyl, tri- chloroethoxycarbonyl, and benzyloxycarbonyl ... directly. Here we report the transport of the pharmacologically active CAI-peptide into human lymphocytes and Human Embryonic Lung cells (HEL) using the BioShuttle platform. Generally, the t...

Ngày tải lên: 08/08/2014, 17:20

... circulation[10,11]. Sim- ilarly, the inflammatory homing selectin ligand, PSGL-1 and its endothelial cell receptors P- and E-selectin, are also known to play a key role in homing and adhesion of HSCs to ... growth factors and cytokines. For example, CXCR4/CXCL12, a general inflammatory chemokine receptor and chemok- ine ligand, is the only known chemokine receptor expressed by HSC...

Ngày tải lên: 08/08/2014, 21:20

... localise to endothelial cells and lymphocytes [97–99]. The type 1 IL-1 receptor is expressed by the endothelium, by the lining cells and by other sublining cells in the RA synovium and the cartilage– pannus ... by lymphocytes and monocytes, and may be functional in lymphocyte adhesion to synovial endothelial cells [33]. CD31 (PECAM-1) is present on most synovial endothe...

Ngày tải lên: 09/08/2014, 01:23

... tyrosine phosphorylated per- sistently (up to 6 hours) in freshly isolated PB and ST CD4 + T cells from RA patients. STAT3 is activated by a variety of cytokines, notably the IL-6 family of cytokines ... [1]. The interaction of IL-10 and IL-10R engages the Janus kinase (JAK) family tyrosine kinases Jak1 and Tyk2, which are constitutively associated with IL-10R1 and type 2 IL- 10R,...

Ngày tải lên: 09/08/2014, 01:24

... production of TNF by T cells, but not by monocytes [13], and that earlier identification of TNF production by monocytes was likely due to T cell contamination of monocytes purified by adherence. Thus, ... the crosstalk between the immune system and bone and in uncovering the mechanism by which sex-steroids, infection and inflammation lead to bone loss by disregulating T lymphocyte fu...

Ngày tải lên: 09/08/2014, 10:20

... inflamed salivary glands in pSS. Locally expressed BAFF, for example by glandular epithelial cells [54] and/ or infiltrating T cells and macrophages [55], may induce the accumulation of self- reactive B cells ... CD27 + memory B cells and CD27 high plasma cells in the inflamed tissues, despite evidence of some clonally expanded B cells. In more detail, peripheral blood B cel...

Ngày tải lên: 09/08/2014, 10:20

... phagocytic cells of the monocyte/ macrophage lineage. Their rapid secretion of many factors that are also released by macrophages, lymphocytes and fibroblasts indicates that they can play similar ... Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998, 93:165-176. 5. Yasuda H, Shima N, Nakagawa N, Mochizuki S-I, Yano K, Fujise N, Sato...

Ngày tải lên: 09/08/2014, 10:20

... lobectomy. Eur J Cardiothorac Surg 2010, 37:36-9. 16. Yoshimoto K, Nomori H, Mori T, Kobayashi H, Ohba Y, Shibata H, Shiraishi S, Kobayashi T: Prediction of pulmonary function after lung lobectomy by subsegments ... Thoracic Society standards [13]. Measurement of Pulmonary Function of Lobes Lung-perfusion SPECT/CT was conducted both before and more than 6 months after surgery, at the s...

Ngày tải lên: 10/08/2014, 09:21

... coronary artery bypass graft surgery, were recruited and evaluated f rom January to 1999 to Janu- ary to 2000, age 40 to 80 years and written informed consent and the study was approved by the ... compli- ance and increased pulmonary resistance, may result in increased respiratory work and oxygen consumption [21,22]. Figure 1 Forced vital capacity, maximal inspiratory pres sure a...

Ngày tải lên: 10/08/2014, 09:21