Báo cáo y học: " Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig" ppsx

... [2-4]. Accordingly, the present study was addressed to investi- gate in the guinea pig the effects of chronic exposure to CS on the endothelial function of pulmonary arteries and the lung expression of endothelial ... participated in the analysis of the data and in the preparation of the manu- script. VIP was involved in the conception of...

Ngày tải lên: 12/08/2014, 14:20

... Thus their actions in vivo depend on their specific concentrations within the microenvironment of the alveolar wall during the course of adaptation to pulmonary hypoxia. Background Pulmonary hypertension ... pulmonary vasodilation with L-arginine in pulmonary hypertension. Circulation 1995, 92(6):1539-45. 34. Mitani Y, Maruyama K, Sakurai M: Prolonged administration...

Ngày tải lên: 12/08/2014, 13:22

... cysteine-rich, metal-binding proteins that function in the maintenance of metal homeostasis and detoxification by forming strong complexes with several types of metal ions [16,17]. Given the existence of MREs in the ... cation-trans- porting P-type ATPases [1–5] and functions in the binding and translocation of copper [6]. Interestingly, multiple copies of metal-respo...

Ngày tải lên: 17/03/2014, 23:20

... hyperplasia of the intimal lining layer and cell infiltration of the synovial sublining were detected and a decrease in bone erosions was observed. (b) Infiltration of inflammatory cells of the joints ... whether IFN-β is influencing monocyte recruitment, survival, and/or retention in the synovial joint. Alternatively, IFN-β may inhibit inflammatory cell infiltration indir...

Ngày tải lên: 09/08/2014, 01:23

... other cytokine production by monocytes [68,118, 119]. Similarly, the pro-inflammatory effects of NPY in concanavalin A-induced paw edema in rat was potentiated by co-application of a DPPIV inhibitor ... finding in RA, although not consistently observed in the synovial fluid (Table 1). Despite the inconsistency in reporting of differing DPPIV levels between non-inflamma...

Ngày tải lên: 09/08/2014, 07:20

... of the syn- ovial lining, expansion of fibroblast population in the synovial connective tissue, and continued collagen deposition [18]. Injection of high amounts of TGF-β, either as a bolus injection or ... restored the IL-1-induced reduction in PG content and increased PG synthesis. TGFβ-induced an elevation in PG content in cartilage of the OA model. TGFβ-induced s...

Ngày tải lên: 09/08/2014, 07:20

... of their hypertension. In addition, patients provided insight as to why the intervention was effective in increasing participation in the intervention. Many of their answers pointed toward findings ... following instruction appears to be ingrained in their reasoning for bringing in the letter. These indivi- dualsstatedtheyweresimplydoingwhattheletter requested of them. ‘...

Ngày tải lên: 11/08/2014, 05:21

... radial head. The reduction was achieved in supination and immobilisation of the elbow in flexion and supination gave a favourable final outcome. In the presence of major distracting injuries like long bone fractures, ... and splints applied to both knees. 12 hours later, the patient complained of pain in the right elbow. There was no previous history of elbow injury...

Ngày tải lên: 11/08/2014, 10:22

... form of BLyS. The molecular mass of the heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis. Binding kinetics and affinity studies The binding affinities an d kinetics ... homotrimers. The reduced potency of the heterotrimer ligands in the pri- mary human B cell-proliferation assay compared with the homotrimeric BLyS may be explained by...

Ngày tải lên: 12/08/2014, 12:20

... a study employing several strains of mice in which neu- trophil influx into the airways was induced by formyl- methionyl-leucyl phenylalanine instillation. This influx resulted in the development of ... the translation of information gained from the development of animal models to improvements in patient care. Specifically, the formal presentations and informal discuss...

Ngày tải lên: 12/08/2014, 18:20