Báo cáo y học: " Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients " ppsx

Báo cáo y học: " Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus" doc

Báo cáo y học: " Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus" doc

... taking hydroxychloroquine, and the inhibition of TLR9 by residual hydroxychloroquine cannot fully explain the abroga- tion of IFN-α observed in one-third of SLE patients (Figure 1). Conclusion In ... as cyclosporine and hydroxychlo- roquine, can affect the function of pDCs. Hydroxychloroquine, in particular, is a known inhibitor of TLR9 signaling; this drug blocks the acidif...
Ngày tải lên : 09/08/2014, 10:23
  • 11
  • 509
  • 0
Báo cáo y học: " Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores" pptx

Báo cáo y học: " Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores" pptx

... levels of pain relief has been shown previously for acute pain [15]. That better therapies should result in more patients with higher levels of relief is not surprising, but individual patient analysis has ... exploratory study is limited by size, and by examining only one trial. Validation would require calculations to be performed on a larger set of trials using individua...
Ngày tải lên : 09/08/2014, 10:23
  • 5
  • 317
  • 0
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx

Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx

... distinct We first wanted to determine whether transcriptional profiles of septicemic patients were distinct from those of healthy individuals and individuals with T2D. We started by carrying out ... cell type (module M2.2) was observed in septic Comparison of phenotypic and clinical information with unsupervised condition clusteringFigure 3 Comparison of phenotypic and clinical in...
Ngày tải lên : 09/08/2014, 20:20
  • 22
  • 395
  • 0
Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

... particularly surprising since most abnormal phenotypes increase in severity with inbreeding, this being particularly striking for phenotypes associated with Egfr [1,12]. However, use of the B6EiC3H- a/A-Egfr wa2 ... Laboratory) and a range of illumination intensities did not detect any masking defects [11]. Previous analyses investigating alterations in locomotor and masking behav...
Ngày tải lên : 10/08/2014, 09:20
  • 5
  • 323
  • 0
Báo cáo y học: "F-fluorodeoxyglucose positron emission tomography-positive sarcoidosis after chemoradiotherapy for Hodgkin’s disease: a case report." ppsx

Báo cáo y học: "F-fluorodeoxyglucose positron emission tomography-positive sarcoidosis after chemoradiotherapy for Hodgkin’s disease: a case report." ppsx

... 25% of patients with pulmonary sarcoidosis [15]; however, this usually takes years to develop and is not a particularly specific finding in Hodgkin’s disease patients treated with bleomycin, ... subsequently treated with two cycles of ABVD (doxorubicin, bleomycin, vinblastine and dacarba- zine) chemotherapy fo llowed by involved field radiother- apy (30gy delivered in 17 fractio...
Ngày tải lên : 10/08/2014, 23:21
  • 6
  • 384
  • 0
Báo cáo y học: " Alveolar macrophages lack CCR2 expression and do not migrate to CCL2" ppt

Báo cáo y học: " Alveolar macrophages lack CCR2 expression and do not migrate to CCL2" ppt

... values are always pre- sented as a ratio of chemokine receptor band intensity to GAPDH band intensity. Flow cytometric analysis In preparation for flow cytometric analysis, freshly iso- lated peripheral ... Genetics/ Microarray Core Facility. All gene chip data analysis was performed in the DHLRI Bioinformatics/Computational Biology (BCB) Core using Data Mining Tool (Affymetrix, Santa...
Ngày tải lên : 11/08/2014, 08:21
  • 10
  • 244
  • 0
Báo cáo y học: "Risk factors predict post-traumatic stress disorder differently in men and women" ppt

Báo cáo y học: "Risk factors predict post-traumatic stress disorder differently in men and women" ppt

... women – not even before controlling for NA – but it did predict PTSD severity in men and remained significant even at the final level of analysis. This is in line with the findings by Bromet et al. [13]. ... http://www.annals-general-psychiatry.com/content/7/1/24 Page 10 of 12 (page number not for citation purposes) men. In support of our hypothesis, anxiety did not...
Ngày tải lên : 08/08/2014, 23:21
  • 12
  • 455
  • 0
Báo cáo y học: "Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study" pptx

Báo cáo y học: "Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study" pptx

... bleeding and perforation, but is often poorly tol- erated because of diarrhoea and abdominal discomfort [3]. Elevation of the intragastric pH by PPIs and high-dose H2RAs reduces the risk of endoscopic ... was performed because of co-morbidity or advanced age. In some of these patients the diagnosis was confirmed during autopsy. Patients were included in the study if they u...
Ngày tải lên : 09/08/2014, 10:20
  • 8
  • 459
  • 0
Báo cáo y học: "Inflammatory cells and bone loss in rheumatoid arthritis" doc

Báo cáo y học: "Inflammatory cells and bone loss in rheumatoid arthritis" doc

... supplementing that normally provided by the chronic inflammatory cells in synovial tissues. This may result in rapid stimulation of bone erosion during disease flares in active RA. Competing interests The ... leucocytes that are exclusively involved in acute inflammatory responses and act as the first line of defence against invading pathogens needs modification. The neutrophi...
Ngày tải lên : 09/08/2014, 10:20
  • 3
  • 363
  • 0
Báo cáo y học: "Inflammatory mediators and cartilage biomarkers in synovial fluid after a single inflammatory insult: a longitudinal experimental study" pps

Báo cáo y học: "Inflammatory mediators and cartilage biomarkers in synovial fluid after a single inflammatory insult: a longitudinal experimental study" pps

... con- firming reproducibility of this model for induction of severe but transient joint inflammation. We further characterized the induced inflammatory response through SF analysis of inflammatory mediators ... adminis- tration of a nonsteroidal anti -inflammatory drug on synovial fluid inflammatory parameters and cartilage biomarkers in inflamed equine joints. That stu...
Ngày tải lên : 09/08/2014, 13:22
  • 8
  • 480
  • 0