Báo cáo y học: " Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro" pps

... arginine in the airways may enhance inflammation by enhancing pro- inflammatory mediator production by epithelial cells. As pro -inflammatory peroxynitrites can also be produced at low arginine ... and NHBE cells. Whereas poly-L- arginine and MBP partially inhibit arginine uptake by NCI-H292 cells, we found no effect of poly-L -arginine on arginine uptake by N...

Ngày tải lên: 12/08/2014, 14:20

... resulted in increased PAO1 binding, did not increase the IL-8 response to PAO1: in this case, the increase in binding of P. aeruginosa in the GM1-incubated cells is probably not coupled to a proinflammatory signaling ... necessarily associated with increased GFP- PAO1 binding, and increased cytokine production was not invariably associated with increased binding of GFP- PAO1. Prov...

Ngày tải lên: 12/08/2014, 18:21

... 2 of 9 induced organ injuries appear to be caused by toxic inflammatory mediators produced by infiltrating acti- vated neutrophils early after thermal injury that are asso- ciated with increased ... thermal injury and post thermal injury plus ear punch. Thermal injury induced a significant systemic inflammatory response, as did the dual-injury model. Serum levels were determined as d...

Ngày tải lên: 11/08/2014, 03:20

... I-TAC in burn wound margin tissue [26]. Severe thermal injury induces a systemic inflammatory response which profoundly augments the local inflammatory wound healing response as evidenced by increased ... Cutaneous dermal burn injury induces a significant local inflammatory response as evidenced by soluble mediator production. Chemokine, proinflammatory cytokine and PGE 2...

Ngày tải lên: 11/08/2014, 06:22

... purity and viability as determined by trypan blue staining. After washing by phosphate-buff- ered saline (PBS) solution and counting the cell numbers, neutrophils were suspended in 10% FCS in RPMI ... to augment cytokine production in previous studies [9,10]. Among inflamma- tory cells, neutrophils are a key player in the inflammatory lung diseases. It is well-known that exce...

Ngày tải lên: 12/08/2014, 14:20

... pravastatin loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocytes sus- pended in PBS, and pravastatin-loaded erythrocytes ... into the erythrocytes should have a degree of water solubility and resistance to degradation within erythrocytes [18]. Certain drugs have been entrapped in erythro- cytes by e...

Ngày tải lên: 25/10/2012, 11:10

... transmembrane domains of connexin and innexin are organized into two closely spaced pairs, which are separated by an intracellular hydrophilic loop (Fig. 2D). Many other functionally related protein families ... of profiles generated by the search algorithm. RESULTS A search strategy was designed for LGICs. The strategy was refined by applying it to custom polypeptide databases, and teste...

Ngày tải lên: 17/03/2014, 23:20

... for their tinnitus. Tinnitus matching is performed by presenting sounds to the ear in which the tinnitus is not perceived, and both tinnitus pitch and tinnitus intensity (above hearing threshold) ... is analysed by Visual Analogue Scale (VAS) while tinnitus severity is analysed by the Tinnitus Questionnaire[18] (TQ). Tinnitus duration is also recorded. This study is approved...

Ngày tải lên: 08/08/2014, 16:23

... CD4 + CD25 + T R cells may occur in the periphery in man. Induction of CD4 + CD25 + T R cells in the periphery The induction of T R cells that resemble the ‘natural’ or thymically derived T R cells described ... alloantigens [57]. T R cells in humans, as in mice, express FoxP3 [58], and individuals with a mutation in the FoxP3 gene develop immunodysregulatory, polyendocr...

Ngày tải lên: 09/08/2014, 01:24

... display a hypoproliferative phenotype in vitro as well as in vivo [33]. Because cytostatic agents act primarily on prolif- erating cells, it is possible that by employing FUdR-dP-con- taining anti-CD134 ... 10 5 cells per sample. For studying anti-CD134 liposome binding to T cells in vitro by flow cytometry, A2b cells were incubated with 5 nmol (lipid) of anti-CD134 liposomes...

Ngày tải lên: 09/08/2014, 06:22