Báo cáo y học: "Dysregulated apoptosis and NFκB expression in COPD subjects" pptx
Báo cáo y học: "Dysregulated apoptosis and NFκB expression in COPD subjects" pptx
... (COPD) is charac- terised by an inflammatory infiltrate consisting mainly of neutrophils [1], with increased neutrophils and inflam- matory mediators in both bronchial tissue and airways of COPD ... recruitment in the airways and inhibition of apoptosis [33,34]. Our findings show that the percentage of neutrophils in early stage apoptosis are significantly reduced in COPD...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Early Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)" pot
... δ- (3,4-dihydroxy-phenyl)-γ-valerolactone and δ-(3-meth- oxy-4-hydroxy-phenyl)-γ-valerolactone and uncovered an antioxidant activity as well as the potential to inhibit release and enzymatic activity ... metabolism. After ingestion of Pycnogenol, for example, two metabo- lites derived from catechin were detected in human urine, δ-(3,4-dihydroxy-phenyl)-γ-valerolactone and δ-(3-meth-...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Lymphocytes, apoptosis and sepsis: making the jump from mice to humans" docx
... blockade of lymphocyte apoptosis is not always protective in sepsis. For example, septic mice lacking MyD88 have decreased lymphocyte apoptosis but a significant increase in mortality [14]. MyD88 is ... pathway of apoptosis, particularly FADD and caspase 8, would have been interesting. In summary, the study by Weber and colleagues reaffirms and advances our knowledge of speci...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
... IGF, insulin-like growth factor; I κ B, inhibitor kappaB; IKK, inhibitor-kappaB kinase; IL, interleukin; IL-R, interleukin receptor; IPA, Ingenuity Path- way Analysis; IPKB, Ingenuity Pathways ... 9:R53 thousands of direct and indirect physical and functional interactions from peer-reviewed publications. The relation- ships in the network include protein-protein interactions, protein bi...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"
... affected initially, and sepsis leads to severe injury in lung tissue [5]. It has been shown that pericytes in lung tissue produce proinflammatory cytokines in response to lipopolysaccharide ... activities and serum proinflammatory cytokine (TNF-α, IL-1β) le- vels were evaluated by enzyme linked immunosor- bent assay (ELISA) using commercially available kits according to the man...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx
... expression levels controlled by proinflammatory cytokines and increased responses to TLR ligands. GM-CSF was shown to play an important role in inflammatory sig- naling in a model of LPS-induced ... ex- pression of TLRs in leukocytes, including pathogen structures and TLR ligands, such as araLAM and LPS, and pro-inflammatory cytokines, including IL-1β, TNF-α, GM-CSF and...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Physical Exercise and Quality of Life in Breast Cancer Survivors" potx
... quality of life (QOL) by maximising functions affected by the disease and its therapy. Preliminary research suggests that exercise may be an effective intervention for enhancing QOL in cancer ... preliminary evidence for the safety, feasibility, and efficacy of exercise training in breast cancer survivors. The aim of this study was to assess the association between physical exerci...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: " Functional inhibition of NF-κB signal transduction in αvβ3 integrin expressing endothelial cells by using RGD-PEG-modified adenovirus with a mutant IκB gene" ppsx
... and differentiation and cell survival and cell death [25]. Among them, IL-6 and IL-8 are mainly produced by endothelial cells and are critical players in the initiation phases of immunity and inflammation. ... stimulation in human umbilical vein endothelial cells (HUVECs) as determined by flow cytometry. Minus and plus signs and denotes resting, non-infected, and TNF-α...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures" doc
... is an inflammatory disease involving joints and other systems including salivary glands. To assess NO production in RA patients, we compared levels of serum, urine, and salivary nitrite and nitrate ... NO in the pathogenesis of joint inflammation. Rodents in animal models of arthritis gener- Figure 3 NOx/creatinine ratios in urine and serumNOx/creatinine ratios in urine and...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: " T cells and post menopausal osteoporosis in murine models" doc
... in elucidating the crosstalk between the immune system and bone and in uncovering the mechanism by which sex-steroids, infection and inflammation lead to bone loss by disregulating T lymphocyte ... approximately 50% of the increase in the number of T cells in the periphery, while the remaining 50% is due to enhanced peripheral expansion. Similarly, thymectomy decreases by approx...
Ngày tải lên: 09/08/2014, 10:20