Báo cáo y học: " Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells" docx

... artificially created. It was reported that proliferation of alveolar epithelial cells peaked two days after the exposure of HGF intratracheally in the rat lung [22]. Meanwhile, hyperplasia of alveolar epithelial ... is a critical pathway involved in the proliferation of many cell types including alveolar epithelial cells. On the basis of our hypothesis that CGRP prol...

Ngày tải lên: 12/08/2014, 14:20

... as soon as possible – ideally even before initiation of therapy – would be of great importance. In recent years gene expression profiling with microarray technology emerged as a powerful tool ... of treatment the gene expression profile of patients benefiting from the therapy changed toward the profile of healthy control individuals, whereas the profile of patients who turned out...

Ngày tải lên: 09/08/2014, 08:22

... http://arthritis-research.com/content/9/4/R84 Page 5 of 10 (page number not for citation purposes) Figure 2 Adhesion assay and number and morphology of colony forming units (CFU)Adhesion assay and number and morphology of colony forming ... CFU Functionality of the cultured CPCs was determined in different ways, that is, CFU potential, migratory capacity and cluster for- mation capaci...

Ngày tải lên: 09/08/2014, 10:20

... analysis of carboxyfluorescein succinimidyl ester (CFSE)-labeled cells. The authors state that functional analysis of proliferation may provide a better tool for identification of specific monocyte subsets ... rise to osteoclasts in vitro based on an analysis of three healthy controls [10]. In the recent study [1], they analyzed monocytes from 13 healthy donors and demon- strated th...

Ngày tải lên: 09/08/2014, 14:21

... Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113–8657, Japan, 4 Department of Hygiene and Public Health, School of Human Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, ... of lymphocytes was only phase-delayed. Granulocytes emigrate from the bloodstream to tissues and cannot recirculate, whereas lymphocytes continuously recirculate from tissues throu...

Ngày tải lên: 10/08/2014, 09:20

... non-invasively applied by means of an electronically controlled nasal mask system recently described in detail by our group [8]. Arterial oxygen satu- ration was monitored by a pulse oxymeter (504; ... 7.6.1.0 software). The number of cells that migrated to the lower side of the membrane was counted by means of light microscopy, operated by an investigator who was blind to the types...

Ngày tải lên: 12/08/2014, 11:22

... airways. Interestingly, uptake of Alexa Fluor 488-l abeled OVA b y DCs was enhanced when PAR-2 was activated using a selective PAR-2 agonist [19]. Clearly, protease-PAR-2 may play an important, yet ... initiation of allergic airway inflammation, BMDCs from wild type and PAR-2-deficient mice were treated in the presence or absence of GC frass and then adoptively transferred into the ai...

Ngày tải lên: 12/08/2014, 14:20

... doroshi73@hanmail.net; Moon Bin Yoo - mbyou@paran.com; Seung Joon Kim - cmcksj@catholic.ac.kr; Hyung Kyu Yoon - cmcyhg@catholic.ac.kr; Young Kyoon Kim - youngkim@catholic.ac.kr; Kwan Hyung Kim - kwan-kim@catholic.ac.kr; ... dependent pathways Jeong Sup Song*, Chun Mi Kang, Moon Bin Yoo, Seung Joon Kim, Hyung Kyu Yoon, Young Kyoon Kim, Kwan Hyung Kim, Hwa Sik Moon and Sung Hak Park Address...

Ngày tải lên: 12/08/2014, 15:20

... uptake of cell-penetrating dyes [13] or their ability to grow out of cartilage tissue [9]. Alternatively, the expression of typical membrane-associated proteins can be employed for the selection of ... Alexa Fluor 488-coupled secondary antibody and for CD166 by using an Alexa Fluor 594-coupled secondary antibody and analyzed by fluorescence microscopy. Co-expression of CD105 and CD1...

Ngày tải lên: 12/08/2014, 15:23

... effects of cytokines and proteolytic enzymes upon a variety of secretory mucin genes including MUC2, MUC5AC, MUC5B and MUC8. Findings from these stud- ies revealed a direct effect of inflammatory mediators upon ... respiratory epithelial cells. Am J Physiol 1999, 276:L835-43. 38. Borchers MT, Carty MP, Leikauf GD: Regulation of human airway mucins by acrolein and inflammatory mediat...

Ngày tải lên: 12/08/2014, 16:20