Báo cáo y học: "Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice" ppt
Báo cáo y học: " Impact of race on efficacy and safety during treatment with olanzapine in schizophrenia, schizophreniform or schizoaffective disorde" pdf
... variables and byanalysis of variance for the continuous variables (bothadjusted by study). The proportion of patients whoexperienced early study discontinuation, TEAEs, and changes in EPS were ... of the initial and final drafts. All authors participated in the analysis and interpretation of the data, and revising the manuscript for criticallyimportant intellectual content. In addition, ... escent and separate results for ethnic minoritiesare infrequently reported . Currently, minimal informa-tion exists to help our understanding of any potentialethnic differences in response and...
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Báo cáo y học: "Activity of the cyclooxygenase 2-prostaglandin-E prostanoid receptor pathway in mice exposed to house dust mite aeroallergens, and impact of exogenous prostaglandin E" pot
... prostaglandin E2 restrains airway mastcell activity in vivo and reduces airway eosinophilia and lung Th2 cytokine overproduction in a house dust mite-inducedmouse model of asthma. Int Arch ... (COX)-2activity in modulating airway reactivity and bronchial inflammation have been investigated in experimentalrodent models of asthma by various groups [10,11],including ours [12,13]. In addition, ... effect on methacholine-induced airwayhyperreactivity. In these animals, the effect of exogenousPGE2 and sulprostone on airway COX-2 activity was meas-ured by evaluating COX-2 mRNA expression in...
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Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
... Questions on LUTS included urinary frequency (2 questions), urgency (2), nocturia (1), incontinence (2) and emptying (1). The questionnaire also included medical and surgical history, demographic ... question-naire on urinary symptoms was given to male pa-tients who visited the general urology outpatient clinic at a Veterans Administration hospital in Brooklyn, NY. It included questions on lower urinary ... B -V8 questionnaire has only been vali-dated in a primary care setting. Validation in a high risk population is still pending. Our study showed that among those with OAB, only 52% had been...
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Báo cáo sinh học: "Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" doc
... partially inhib-its the antiviral actions of IFN-α, involving inhibition of IFN-α induced Stat1 tyrosine phosphorylation. Analysis of the effects of chronic ethanol administration on basal and IFN-α ... HCV replication in the presence of IFN. Inhibition of Jak-Stat signaling may involve ethanol perturbation of IFN-α induced changes in membrane fluidity, inhibition of IFN binding to its receptor, ... activationinvolves phosphorylation on conserved tyrosines atamino acid positions 701 and 690, respectively, whilephosphorylation of Stat1 also occurs on conserved serineamino acid at position 727 and provides...
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báo cáo hóa học:"Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" potx
... pres-ence of exogenously added IFN-α, ethanol partially inhib-its the antiviral actions of IFN-α, involving inhibition of IFN-α induced Stat1 tyrosine phosphorylation. Analysis of the effects of chronic ... HCV replication in the presence of IFN. Inhibition of Jak-Stat signaling may involve ethanol perturbation of IFN-α induced changes in membrane fluidity, inhibition of IFN binding to its receptor, ... University, New York, NY, 3Department of Pathology, University of Washington, Seattle, USA, 4Department of Pathology, University of Washington, Seattle, USA and 5Departments of Laboratory Medicine,...
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Báo cáo y học: "Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage" pdf
... catabolic responses[32,33]. Besides control of gene expression, protein synthe-sis, and secretion, the biological activity of cytokines and growth factors is regulated by binding to ECM proteins suchas ... Sulfexpression was also determined in murine knee joints.Interestingly, Sulf expression was high at 1 month of age and Figure 3Localization of Sulf-1 and Sulf-2 in normal-appearing and fibrillated cartilage ... a marked increase in Sulf-2 expression at 9 months and in Sulf-1 expression at 12months. In murine knee joints (n = 8), there was high Sulfexpression at 1 month of age, followed by a decrease...
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Báo cáo y học: "Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer" potx
... specifythe instrumentation type, sampling mode and analysistools in order to allow inclusion of this study in thegrowing database of cancer studies using actigraphy[16].This report investigates ... first cycle of therapy, to ach ieve aminimum of 48 hours of high quality continuous activitydata. The timing and conditions of actigraphy measure-ment were necessarily different at each of the ... actigraphicmeasure of sleep and activity can accurately and quantita-tively confirm t he patient s elf-report of sleep qua lity. In addition to a dysfunctional circadian activityrhythm, many of the patien...
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Báo cáo y học: "Kinetics of non-structural protein 1, IgM and IgG antibodies in dengue type 1 primary infection" pps
... of onset, and slowly increasing to 100% by day 15 of illness. Combining the results of NS1 and IgM antibody detection allowed positive diagnosis in 96.9% -100% for samples taken after day 3 of ... detectable on the third day of onset with the positive rate of 42.9%, and rapidlyincreasing to 100% by day 8 of illness. Anti-dengue IgG antibody was detectable on the fifth day of onset with ... and yellow fevervirus (YFV). In addition, IgM antibody response variesconsiderably among the individuals due to host humoralimmune response or depending on whether a primaryvs a secondary...
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Báo cáo y học: " Prevalence of a virus similar to human hepatitis B virus in swine" ppt
... 3,3-diaminobenzidin (DAB;Zymed Laboratories Inc) at room temperature for 10 min in the dark. Finally, sections were stained with hematoxy-lin for 8 min after rinsing for 3 times in PBS-T, dehy-drated, ... understand-ing of the v irology and immunology of HBV infection and disease pathogenesis, including major sequelae likechronic hepatitis and hepatocellular carcinoma. Of the 350 million to 400 million individuals ... cleartransmission routes in many people in China [34]. Theidentification of the SHBV strain confirms that a novelclass of hepadnaviridae exists in swine populations. And thus brings about a lot of questions....
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Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... sampling to iden-tify key informants, including physicians, nurses, and clinical officers, based on their locations and roles duringthe conflict. A trained facilitator conducted 9 interviewsusing ... Board of the IndianaUniversity School of Medicine (Indianapolis, Indiana).Informed consent was obtained for key informant inter-views, and all clinical investigation was conducted accord-ing ... includingthose caring for orphans.▪ The second difficulty, that continued beyond the immedi-ate crisis, was lack of money. No one had transport money and getting to the clinic was so difficult and...
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