Báo cáo y học: "Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice" ppt

... variables and by analysis of variance for the continuous variables (both adjusted by study). The proportion of patients who experienced early study discontinuation, TEAEs, and changes in EPS were ... of the initial and final drafts. All authors participated in the analysis and interpretation of the data, and revising the manuscript for critically important intellectual c...

Ngày tải lên: 11/08/2014, 16:22

... prostaglandin E 2 restrains airway mast cell activity in vivo and reduces airway eosinophilia and lung Th 2 cytokine overproduction in a house dust mite-induced mouse model of asthma. Int Arch ... (COX)-2 activity in modulating airway reactivity and bronchial inflammation have been investigated in experimental rodent models of asthma by various groups [10,11], includin...

Ngày tải lên: 11/08/2014, 08:22

... Questions on LUTS included urinary frequency (2 questions), urgency (2), nocturia (1), incontinence (2) and emptying (1). The questionnaire also included medical and surgical history, demographic ... question- naire on urinary symptoms was given to male pa- tients who visited the general urology outpatient clinic at a Veterans Administration hospital in Brooklyn, NY. It includ...

Ngày tải lên: 25/10/2012, 11:35

... partially inhib- its the antiviral actions of IFN-α, involving inhibition of IFN-α induced Stat1 tyrosine phosphorylation. Analysis of the effects of chronic ethanol administration on basal and IFN-α ... HCV replication in the presence of IFN. Inhibition of Jak-Stat signaling may involve ethanol perturbation of IFN-α induced changes in membrane fluidity, inhibition of...

Ngày tải lên: 19/06/2014, 08:20

... pres- ence of exogenously added IFN-α, ethanol partially inhib- its the antiviral actions of IFN-α, involving inhibition of IFN-α induced Stat1 tyrosine phosphorylation. Analysis of the effects of chronic ... HCV replication in the presence of IFN. Inhibition of Jak-Stat signaling may involve ethanol perturbation of IFN-α induced changes in membrane fluidity, inhibition...

Ngày tải lên: 20/06/2014, 04:20

... catabolic responses [32,33]. Besides control of gene expression, protein synthe- sis, and secretion, the biological activity of cytokines and growth factors is regulated by binding to ECM proteins such as ... Sulf expression was also determined in murine knee joints. Interestingly, Sulf expression was high at 1 month of age and Figure 3 Localization of Sulf-1 and Sulf-2 in...

Ngày tải lên: 09/08/2014, 10:23

... specify the instrumentation type, sampling mode and analysis tools in order to allow inclusion of this study in the growing database of cancer studies using actigraphy [16]. This report investigates ... first cycle of therapy, to ach ieve a minimum of 48 hours of high quality continuous activity data. The timing and conditions of actigraphy measure- ment were necessarily d...

Ngày tải lên: 10/08/2014, 09:20

... of onset, and slowly increasing to 100% by day 15 of illness. Combining the results of NS1 and IgM antibody detection allowed positive diagnosis in 96.9% -100% for samples taken after day 3 of ... detectable on the third day of onset with the positive rate of 42.9%, and rapidly increasing to 100% by day 8 of illness. Anti-dengue IgG antibody was detectable on the fif...

Ngày tải lên: 11/08/2014, 21:22

... 3,3-diaminobenzidin (DAB; Zymed Laboratories Inc) at room temperature for 10 min in the dark. Finally, sections were stained with hematoxy- lin for 8 min after rinsing for 3 times in PBS-T, dehy- drated, ... understand- ing of the v irology and immunology of HBV infection and disease pathogenesis, including major sequelae like chronic hepatitis and hepatocellular carcinoma. Of...

Ngày tải lên: 12/08/2014, 04:20

... sampling to iden- tify key informants, including physicians, nurses, and clinical officers, based on their locations and roles during the conflict. A trained facilitator conducted 9 interviews using ... Board of the Indiana University School of Medicine (Indianapolis, Indiana). Informed consent was obtained for key informant inter- views, and all clinical investigation was conduct...

Ngày tải lên: 25/10/2012, 10:31